[3-(Trifluoromethyl)phenyl]hydrazine (CED0044184)

Record Information
Version1.0
Creation Date2026-04-04 18:48:26 UTC
Update Date2026-08-24 06:53:42 UTC
SynCED IDCED0044184
Secondary Accession Numbers
  • CHEM078158
Identification
Common Name[3-(Trifluoromethyl)phenyl]hydrazine
ClassSmall Molecule
Description
[3-(Trifluoromethyl)phenyl]hydrazine belongs to the trifluoromethylbenzenes, a subclass of benzene and substituted derivatives within the organic compounds. This benzenoid compound has the chemical formula C7H7F3N2 and an average molecular weight of 176.14 g/mol.
Contaminant TypeNot Available
Chemical Structure
MOLSDFPDBSMILESInChI
SynonymsNot Available
Chemical FormulaC7H7F3N2
Average Molecular Mass176.142 g/mol
Monoisotopic Mass176.056 g/mol
CAS Registry Number368-78-5
IUPAC NameNot Available
Traditional NameNot Available
SMILESNNC1=CC=CC(=C1)C(F)(F)F
InChI IdentifierInChI=1/C7H7F3N2/c8-7(9,10)5-2-1-3-6(4-5)12-11/h1-4,12H,11H2
InChI KeyRSESUCWJKLHXEZ-UHFFFAOYSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Toxicity Values
Toxicity ValueOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalToxicity RatingReference
218.0 Log mg/kg [120:390]RatLD50oralpredictedNot AvailableNot Available
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionDescriptionReference
Exposure Sources
Source IDSourceSectorReference
CEDs000010Insecticides?Insecticides are synthetic chemicals designed to control or eliminate insect pests that threaten crops and other agricultural products.Agriculture & land managementPubChem
CEDs000511Conductors Or Conductive Bodies Characterised By The Conductive Materials?Conductors, or conductive bodies, are materials that allow the flow of electrical current, typically made from metals such as copper, aluminum, or silver.Electrical & Electronic EquipmentPubChem
CEDs000603Nematocides?Nematocides are synthetic chemicals specifically designed to control nematodes, which are microscopic roundworms that can cause significant damage to crops and plants.Agriculture & land managementPubChem
Pathways
0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureSecernin-3Q0VDG4HumansPredicted (SEA)
Prediction Confidence Score
0.387
Applicability Domain
0.387
Statistical Significance
4.00e-05
Supporting Reference Compounds
1
E-value
0.311397
Vascular endothelial growth factor receptor 2 structureClick to view 3D structureVascular endothelial growth factor receptor 2P35968HumansPredicted (SEA)
Prediction Confidence Score
0.359
Applicability Domain
0.365
Statistical Significance
0.0559
Supporting Reference Compounds
1660
E-value
434.866
Epidermal growth factor receptor structureClick to view 3D structureEpidermal growth factor receptorP00533HumansPredicted (SEA)
Prediction Confidence Score
0.359
Applicability Domain
0.383
Statistical Significance
0.0496
Supporting Reference Compounds
1301
E-value
385.976
Mast/stem cell growth factor receptor Kit structureClick to view 3D structureMast/stem cell growth factor receptor KitP10721HumansPredicted (SEA)
Prediction Confidence Score
0.356
Applicability Domain
0.365
Statistical Significance
0.0395
Supporting Reference Compounds
905
E-value
307.894
Tyrosine-protein kinase Lck structureClick to view 3D structureTyrosine-protein kinase LckP06239HumansPredicted (SEA)
Prediction Confidence Score
0.355
Applicability Domain
0.365
Statistical Significance
0.0503
Supporting Reference Compounds
1130
E-value
391.815
Mitogen-activated protein kinase 14 structureClick to view 3D structureMitogen-activated protein kinase 14Q16539HumansPredicted (SEA)
Prediction Confidence Score
0.355
Applicability Domain
0.365
Statistical Significance
0.0298
Supporting Reference Compounds
668
E-value
231.679
Prostaglandin G/H synthase 2 structureClick to view 3D structureProstaglandin G/H synthase 2P35354HumansPredicted (SEA)
Prediction Confidence Score
0.355
Applicability Domain
0.462
Statistical Significance
0.0048
Supporting Reference Compounds
201
E-value
37.4455
Click to view 3D structureTelomerase reverse transcriptaseQ673L6Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.35
Applicability Domain
0.35
Statistical Significance
1.30e-04
Supporting Reference Compounds
1
E-value
1.01204
Aurora kinase A structureClick to view 3D structureAurora kinase AO14965HumansPredicted (SEA)
Prediction Confidence Score
0.345
Applicability Domain
0.367
Statistical Significance
0.049
Supporting Reference Compounds
996
E-value
381.85
Proto-oncogene tyrosine-protein kinase Src structureClick to view 3D structureProto-oncogene tyrosine-protein kinase SrcP12931HumansPredicted (SEA)
Prediction Confidence Score
0.345
Applicability Domain
0.358
Statistical Significance
0.0541
Supporting Reference Compounds
1158
E-value
421.476
Macrophage colony-stimulating factor 1 receptor structureClick to view 3D structureMacrophage colony-stimulating factor 1 receptorP07333HumansPredicted (SEA)
Prediction Confidence Score
0.344
Applicability Domain
0.358
Statistical Significance
0.0439
Supporting Reference Compounds
833
E-value
342.147
Receptor tyrosine-protein kinase erbB-4 structureClick to view 3D structureReceptor tyrosine-protein kinase erbB-4Q15303HumansPredicted (SEA)
Prediction Confidence Score
0.343
Applicability Domain
0.367
Statistical Significance
0.0357
Supporting Reference Compounds
591
E-value
278.0
Vascular endothelial growth factor receptor 1 structureClick to view 3D structureVascular endothelial growth factor receptor 1P17948HumansPredicted (SEA)
Prediction Confidence Score
0.342
Applicability Domain
0.358
Statistical Significance
0.0388
Supporting Reference Compounds
711
E-value
301.977
Vascular endothelial growth factor receptor 3 structureClick to view 3D structureVascular endothelial growth factor receptor 3P35916HumansPredicted (SEA)
Prediction Confidence Score
0.342
Applicability Domain
0.358
Statistical Significance
0.034
Supporting Reference Compounds
687
E-value
264.765
Insulin-like growth factor 1 receptor structureClick to view 3D structureInsulin-like growth factor 1 receptorP08069HumansPredicted (SEA)
Prediction Confidence Score
0.341
Applicability Domain
0.358
Statistical Significance
0.0445
Supporting Reference Compounds
785
E-value
346.74
Tyrosine-protein kinase SYK structureClick to view 3D structureTyrosine-protein kinase SYKP43405HumansPredicted (SEA)
Prediction Confidence Score
0.341
Applicability Domain
0.358
Statistical Significance
0.0383
Supporting Reference Compounds
625
E-value
297.929
Tyrosine-protein kinase ABL1 structureClick to view 3D structureTyrosine-protein kinase ABL1P00519HumansPredicted (SEA)
Prediction Confidence Score
0.34
Applicability Domain
0.358
Statistical Significance
0.0511
Supporting Reference Compounds
927
E-value
398.043
Receptor tyrosine-protein kinase erbB-2 structureClick to view 3D structureReceptor tyrosine-protein kinase erbB-2P04626HumansPredicted (SEA)
Prediction Confidence Score
0.34
Applicability Domain
0.358
Statistical Significance
0.0386
Supporting Reference Compounds
674
E-value
300.498
Cyclin-dependent kinase 1 structureClick to view 3D structureCyclin-dependent kinase 1P06493HumansPredicted (SEA)
Prediction Confidence Score
0.34
Applicability Domain
0.358
Statistical Significance
0.0336
Supporting Reference Compounds
715
E-value
261.963
Activator of 90 kDa heat shock protein ATPase homolog 1 structureClick to view 3D structureActivator of 90 kDa heat shock protein ATPase homolog 1O95433HumansPredicted (SEA)
Prediction Confidence Score
0.34
Applicability Domain
0.34
Statistical Significance
2.30e-04
Supporting Reference Compounds
1
E-value
1.79053
Fibroblast growth factor receptor 1 structureClick to view 3D structureFibroblast growth factor receptor 1P11362HumansPredicted (SEA)
Prediction Confidence Score
0.339
Applicability Domain
0.358
Statistical Significance
0.0534
Supporting Reference Compounds
1010
E-value
415.715
Angiopoietin-1 receptor structureClick to view 3D structureAngiopoietin-1 receptorQ02763HumansPredicted (SEA)
Prediction Confidence Score
0.335
Applicability Domain
0.365
Statistical Significance
0.0224
Supporting Reference Compounds
285
E-value
174.771
Proto-oncogene tyrosine-protein kinase receptor Ret structureClick to view 3D structureProto-oncogene tyrosine-protein kinase receptor RetP07949HumansPredicted (SEA)
Prediction Confidence Score
0.334
Applicability Domain
0.358
Statistical Significance
0.0525
Supporting Reference Compounds
764
E-value
409.098
Tyrosine-protein kinase BTK structureClick to view 3D structureTyrosine-protein kinase BTKQ06187HumansPredicted (SEA)
Prediction Confidence Score
0.334
Applicability Domain
0.358
Statistical Significance
0.0587
Supporting Reference Compounds
798
E-value
457.364
Serine/threonine-protein kinase pim-1 structureClick to view 3D structureSerine/threonine-protein kinase pim-1P11309HumansPredicted (SEA)
Prediction Confidence Score
0.333
Applicability Domain
0.358
Statistical Significance
0.0525
Supporting Reference Compounds
967
E-value
408.553
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available