Brivaracetam (CED0006590)

Record Information
Version1.0
Creation Date2026-04-05 10:45:41 UTC
Update Date2026-08-18 12:59:52 UTC
Accession NumberCHEM099483
Identification
Common NameBrivaracetam
ClassSmall Molecule
Description
Brivaracetam is an organic compound with the formula C11H20N2O2 and an average molecular weight of 212.29 g/mol. Brivaracetam belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. The compound is found in or released from one recorded source: healthcare, pharmaceuticals & veterinary products, where it is used as an antiepileptic. Recorded exposure routes for this substance include oral and intravenous administration. Brivaracetam interacts with 15 recorded protein targets, acting as an inhibitor or having an unknown effect on synaptic vesicle glycoprotein 2A (SV2A), sodium channel protein type 1 subunit alpha (SCN1A), sodium channel protein type 4 subunit alpha (SCN4A), sodium channel regulatory subunit beta-2 (SCN2B), and 11 other proteins.
Contaminant TypeNot Available
Chemical Structure
MOLSDFPDBSMILESInChI
SynonymsNot Available
Chemical FormulaC11H20N2O2
Average Molecular Mass212.293 g/mol
Monoisotopic Mass212.152 g/mol
CAS Registry Number357336-20-0
IUPAC NameNot Available
Traditional NameNot Available
SMILESCCC[C@H]1CN([C@@H](CC)C(N)=O)C(=O)C1
InChI IdentifierInChI=1S/C11H20N2O2/c1-3-5-8-6-10(14)13(7-8)9(4-2)11(12)15/h8-9H,3-7H2,1-2H3,(H2,12,15)/t8-,9+/m1/s1
InChI KeyMSYKRHVOOPPJKU-BDAKNGLRSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
Predicted GC-MSPredicted GC-MS Spectrumsplash10-00ko-9600000000-ff6fdfd2af8595903280Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03di-0590000000-cfc92f036264ae62372dNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-014j-1910000000-422e10556e2fdca17ca1Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-00kf-9200000000-484b630dade2a9c865d5Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03di-1390000000-20cbe3a32505bdae1c8bNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-02tc-5930000000-4eb7ac13ac5929f7fffeNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0006-9000000000-4679af6e0d9f73478d07Not AvailableView Spectrum
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity Values
Toxicity ValueUnitValue RangeOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalReference
458.0Log mg/kg[260:820]RatLD50oralpredictedNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
371AntiepilepticsHealthcare, pharmaceuticals & veterinary productsNot Available
Pathways
2 pathways
Brivaracetam Drug Metabolism Action Pathway
Brivaracetam Drug Metabolism Action Pathway
Brivaracetam Predicted Metabolism Pathway
Brivaracetam Predicted Metabolism Pathway
Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureSynaptic vesicle glycoprotein 2AQ02563Rattus norvegicusPredicted (SEA)0.0778492
Click to view 3D structureMHC class IIQ6MGC4Rattus norvegicusPredicted (SEA)96.533
Click to view 3D structureNeuraminidaseP03468Influenza A virus (A/Puerto Rico/8/1934(H1N1))Predicted (SEA)24.9118
Click to view 3D structureNeuraminidaseB4URF0Influenza A virusPredicted (SEA)41.4936
Click to view 3D structureNeuraminidaseP03469Influenza A virus (strain A/USSR/90/1977 H1N1)Predicted (SEA)16.8154
Click to view 3D structureNeuraminidaseA5Z252Influenza A virusPredicted (SEA)26.1573
Click to view 3D structureNeuraminidaseQ9IGQ6Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza Avirus (strain A/South Carolina/1/1918 H1N1))Predicted (SEA)2.17978
Neuraminidase structureClick to view 3D structureNeuraminidaseP03474Influenza B virus (strain B/Lee/1940)Predicted (SEA)8.87481
Click to view 3D structureNeuraminidaseP03470Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus(strain A/WS/1933 H1N1))Predicted (SEA)7.16213
Click to view 3D structureSialidaseP10481Clostridium perfringensPredicted (SEA)29.427
D(2) dopamine receptor structureClick to view 3D structureD(2) dopamine receptorP14416HumansPredicted (SEA)4671.58
Click to view 3D structureProstaglandin E2 receptor EP1 subtypeP35375Mus musculusPredicted (SEA)302.756
Click to view 3D structureProstaglandin E2 receptor EP3 subtypeP30557Mus musculusPredicted (SEA)407.463
Click to view 3D structureProstaglandin E2 receptor EP4 subtypeP32240Mus musculusPredicted (SEA)445.687
Click to view 3D structureProstaglandin E2 receptor EP2 subtypeQ62053Mus musculusPredicted (SEA)263.753
Platelet glycoprotein 4 structureClick to view 3D structurePlatelet glycoprotein 4P16671HumansPredicted (SEA)18.9952
D(3) dopamine receptor structureClick to view 3D structureD(3) dopamine receptorP35462HumansPredicted (SEA)4533.08
Prostaglandin E2 receptor EP2 subtype structureClick to view 3D structureProstaglandin E2 receptor EP2 subtypeP43116HumansPredicted (SEA)1221.92
Click to view 3D structureNeuraminidaseC4LRQ6Influenza A virusPredicted (SEA)9.03051
Prostaglandin E2 receptor EP4 subtype structureClick to view 3D structureProstaglandin E2 receptor EP4 subtypeP35408HumansPredicted (SEA)1347.96
Click to view 3D structureExtended-spectrum beta-lactamase PER-6D5HSX5Aeromonas allosaccharophilaPredicted (SEA)1.55698
Click to view 3D structureADC-14 proteinQ0VTR6Acinetobacter genomosp. 3Predicted (SEA)1.55698
Click to view 3D structureBeta-lactamase SHV-11Q7X575Escherichia coliPredicted (SEA)1.55698
Click to view 3D structureADC-16 proteinQ0VTR8Acinetobacter genomosp. 3Predicted (SEA)1.55698
Click to view 3D structureTripeptidyl-peptidase 2Q64560Rattus norvegicusPredicted (SEA)37.4455
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available