Peramivir (CED0005669)

Record Information

Version

1.0

Creation Date

2026-04-05 11:54:39 UTC

Update Date

2026-05-14 18:22:13 UTC

SynCED ID

CED0005669

Secondary Accession Numbers

CHEM100746

Identification

Common Name

Peramivir

Class

Small Molecule

Description

Peramivir is an organic compound with the formula C15H28N4O4 and an average molecular weight of 328.41 g/mol. Peramivir belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. It acts as an inhibitor of the protein target Neuraminidase (NA). The compound is found in or released from two recorded sources: household cleaning and consumer products, specifically non electric simulated smoking devices, and healthcare, pharmaceuticals and veterinary products, specifically antivirals. The recorded route of exposure for this compound is intravenous.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₁₅H₂₈N₄O₄

Average Molecular Mass

328.413 g/mol

Monoisotopic Mass

328.211 g/mol

CAS Registry Number

330600-85-6

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

CCC(CC)[C@H](NC(C)=O)[C@@H]1[C@H](O)[C@H](C[C@H]1N=C(N)N)C(O)=O

InChI Identifier

InChI=1S/C15H28N4O4/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19)/t9-,10+,11+,12-,13+/m0/s1

InChI Key

XRQDFNLINLXZLB-CKIKVBCHSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

antiviral drug (PMC5687045 )?
antiviral agent (PMC9919865 )?
EC 3.2.1.18 (exo-α-sialidase) inhibitor (PMC7874133 , PMC6274581 )?

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted GC-MS	Predicted GC-MS Spectrum	splash10-006x-9561000000-72733980f57e56c7b21f	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-03fr-0089000000-5321e33479a888363bcb	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-03xu-1191000000-36bd5d5690cb773d5631	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-03di-9200000000-b095abc093183b12f7a1	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-00n0-1093000000-9494bb34d3cd2286b6f1	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-00ko-1190000000-119f6b33168a8fa7ea95	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-052f-9010000000-47ed4dae20d384b34e76	Not Available	View Spectrum

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
2513.0 Log mg/kg [1400:4500]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Description	Reference
influenza	Not Available	Not Available	A viral infectious disease that results in infection, located in respiratory tract, has material basis in Influenzavirus A, has material basis in Influenzavirus B, or has material basis in Influenzavirus C, which are transmitted by droplet spread of oronasal secretions during coughing, sneezing, or talking from an infected person. It is a highly contagious disease that affects birds and mammals and has symptom chills, has symptom fever, has symptom sore throat, has symptom runny nose, has symptom muscle pains, has symptom severe headache, has symptom cough, and has symptom weakness. (DO)	PMC6274581
avian influenza	Not Available	Not Available	Not Available	PMC8247473

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000351	Antivirals?Antivirals are synthetic chemicals designed to inhibit the replication of viruses and are widely used in the treatment of viral infections in humans and animals.	Healthcare, pharmaceuticals & veterinary products	Not Available
CEDs000518	Electrically Stimulated Smoking Devices?Electrically stimulated smoking devices, commonly known as e-cigarettes or vape pens, utilize electrical components to heat a liquid solution, often containing nicotine, flavorings, and other additives, to produce an aerosol for inhalation.	Electrical & Electronic Equipment	PubChem
CEDs000545	Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.	Food, food processing & cookware	PubChem
CEDs000559	Non Electric Simulated Smoking Devices?Non-electric simulated smoking devices, often designed to mimic the experience of smoking without combustion, can be sources of synthetic chemical contamination due to the materials and chemicals used in their construction and operation.	Household cleaning & consumer products	PubChem
CEDs000580	Manufacture Preparation Of Tobacco Products?The manufacture and preparation of tobacco products involve various processes that can result in the introduction of synthetic chemicals into the environment.	Industrial manufacturing & chemical processing	PubChem
CEDs000605	Pest Repellants?Pest repellents, often formulated from synthetic chemicals, are widely used to protect crops from insect infestations and other pests.	Agriculture & land management	PubChem
CEDs000632	Apparel?Apparel production often involves the use of various synthetic chemicals, including dyes, finishing agents, and preservatives.	Textiles, leather & furnishings	PubChem
CEDs000696	Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.	Industrial manufacturing & chemical processing	PubChem
CEDs000727	Printing Machines Or Presses?Printing machines or presses commonly utilize synthetic chemicals such as inks, solvents, and cleaning agents.	Paper, pulp & fiber products	PubChem

Pathways

2 pathwaysPathway Source: PathBank

Peramivir Action Pathway

Peramivir Drug Metabolism Action Pathway

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Neuraminidase	Q9IGQ6	Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza Avirus (strain A/South Carolina/1/1918 H1N1))	Predicted (SEA)	Prediction Confidence Score 0.658 Applicability Domain 0.681 Statistical Significance 1.00e-05 Supporting Reference Compounds 2 E-value 0.0778492
Click to view 3D structure	Neuraminidase	B4URF0	Influenza A virus	Predicted (SEA)	Prediction Confidence Score 0.358 Applicability Domain 0.635 Statistical Significance 7.50e-04 Supporting Reference Compounds 42 E-value 5.83869
Click to view 3D structure	Neuraminidase	A5Z252	Influenza A virus	Predicted (SEA)	Prediction Confidence Score 0.327 Applicability Domain 0.635 Statistical Significance 6.80e-04 Supporting Reference Compounds 18 E-value 5.29375
Click to view 3D structure	Neuraminidase	P03470	Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus(strain A/WS/1933 H1N1))	Predicted (SEA)	Prediction Confidence Score 0.326 Applicability Domain 0.635 Statistical Significance 6.80e-04 Supporting Reference Compounds 10 E-value 5.29375
Click to view 3D structure	Neuraminidase	C4LRQ6	Influenza A virus	Predicted (SEA)	Prediction Confidence Score 0.322 Applicability Domain 0.635 Statistical Significance 6.40e-04 Supporting Reference Compounds 9 E-value 4.98235
Click to view 3D structure	Neuraminidase	P03468	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	Predicted (SEA)	Prediction Confidence Score 0.321 Applicability Domain 0.635 Statistical Significance 7.70e-04 Supporting Reference Compounds 34 E-value 5.99439
Click to view 3D structure	Neuraminidase	P03474	Influenza B virus (strain B/Lee/1940)	Predicted (SEA)	Prediction Confidence Score 0.319 Applicability Domain 0.635 Statistical Significance 7.70e-04 Supporting Reference Compounds 13 E-value 5.99439
Click to view 3D structure	Neuraminidase	P03471	Influenza A virus (A/Memphis/1/1971(H3N2))	Predicted (SEA)	Prediction Confidence Score 0.316 Applicability Domain 0.635 Statistical Significance 6.70e-04 Supporting Reference Compounds 13 E-value 5.2159
Click to view 3D structure	SPRY domain-containing SOCS box protein 2	Q99619	Humans	Predicted (SEA)	Prediction Confidence Score 0.262 Applicability Domain 0.262 Low confidence Statistical Significance 0.0044 Supporting Reference Compounds 1 E-value 34.3315
Click to view 3D structure	Sialidase	P10481	Clostridium perfringens	Predicted (SEA)	Prediction Confidence Score 0.231 Applicability Domain 0.318 Statistical Significance 0.0033 Supporting Reference Compounds 22 E-value 26.0016
Click to view 3D structure	Melanocortin receptor 5	P41149	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.22 Applicability Domain 0.22 Low confidence Statistical Significance 0.0433 Supporting Reference Compounds 29 E-value 337.321
Click to view 3D structure	Synaptic vesicle glycoprotein 2A	Q02563	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.217 Applicability Domain 0.217 Low confidence Statistical Significance 4.80e-04 Supporting Reference Compounds 1 E-value 3.73676
Click to view 3D structure	Melanocortin receptor 4	P56450	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.214 Applicability Domain 0.22 Low confidence Statistical Significance 0.0577 Supporting Reference Compounds 34 E-value 448.956
Click to view 3D structure	Melanocyte-stimulating hormone receptor	Q01727	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.211 Applicability Domain 0.22 Low confidence Statistical Significance 0.0522 Supporting Reference Compounds 31 E-value 406.139
Click to view 3D structure	Neuraminidase	P03469	Influenza A virus (strain A/USSR/90/1977 H1N1)	Predicted (SEA)	Prediction Confidence Score 0.21 Applicability Domain 0.224 Low confidence Statistical Significance 0.0067 Supporting Reference Compounds 13 E-value 51.9254
Click to view 3D structure	Melanocortin receptor 4	P32245	Humans	Predicted (SEA)	Prediction Confidence Score 0.209 Applicability Domain 0.22 Low confidence Statistical Significance 0.1787 Supporting Reference Compounds 96 E-value 1390.93
Click to view 3D structure	Thrombospondin-1	P07996	Humans	Predicted (SEA)	Prediction Confidence Score 0.209 Applicability Domain 0.209 Low confidence Statistical Significance 0.0155 Supporting Reference Compounds 1 E-value 120.9
Click to view 3D structure	Dihydroxyacetone phosphate acyltransferase	O15228	Humans	Predicted (SEA)	Prediction Confidence Score 0.206 Applicability Domain 0.206 Low confidence Statistical Significance 0.0099 Supporting Reference Compounds 1 E-value 77.3043
Click to view 3D structure	Metabotropic glutamate receptor 8	P70579	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.204 Applicability Domain 0.235 Low confidence Statistical Significance 0.0554 Supporting Reference Compounds 28 E-value 431.674
Click to view 3D structure	Serine protease 1	P00760	Bos taurus	Predicted (SEA)	Prediction Confidence Score 0.204 Applicability Domain 0.23 Low confidence Statistical Significance 0.1558 Supporting Reference Compounds 74 E-value 1212.58
Click to view 3D structure	Melanocortin receptor 3	P41968	Humans	Predicted (SEA)	Prediction Confidence Score 0.203 Applicability Domain 0.22 Low confidence Statistical Significance 0.1063 Supporting Reference Compounds 45 E-value 827.537
Click to view 3D structure	Putative inactive group IIC secretory phospholipase A2	Q5R387	Humans	Predicted (SEA)	Prediction Confidence Score 0.203 Applicability Domain 0.203 Low confidence Statistical Significance 0.007 Supporting Reference Compounds 1 E-value 54.6502
Click to view 3D structure	Glutamate receptor ionotropic, kainate 4	Q01812	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.203 Applicability Domain 0.22 Low confidence Statistical Significance 9.00e-05 Supporting Reference Compounds 2 E-value 0.700643
Click to view 3D structure	Melanocyte-stimulating hormone receptor	Q01726	Humans	Predicted (SEA)	Prediction Confidence Score 0.203 Applicability Domain 0.22 Low confidence Statistical Significance 0.0802 Supporting Reference Compounds 38 E-value 624.662
Click to view 3D structure	Metabotropic glutamate receptor 4	P31423	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.202 Applicability Domain 0.235 Low confidence Statistical Significance 0.1107 Supporting Reference Compounds 38 E-value 861.635