L-homocysteine (CED0001137)

Record Information

Version

1.0

Creation Date

2026-04-05 19:18:39 UTC

Update Date

2026-04-05 19:18:39 UTC

SynCED ID

CED0001137

Secondary Accession Numbers

CHEM106818

Identification

Common Name

L-homocysteine

Class

Small Molecule

Description

L-homocysteine is an organic compound with the formula C4H9NO2S. L-homocysteine belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. This substance is found in or released from one recorded source: electrical and electronic equipment, specifically antennas.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₄H₉NO₂S

Average Molecular Mass

Not Available

Monoisotopic Mass

135.035 g/mol

CAS Registry Number

Not Available

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

Not Available

InChI Identifier

InChI=1/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)

InChI Key

FFFHZYDWPBMWHY-VKHMYHEASA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

metabolite (PMC11482134 )?A chemical produced during metabolism process, as an intermediate or end-product
neurotoxin (PMC7337253 , PMC7337253 )?A chemical substance that interferes with the normal functioning of the nervous system
uremic toxin (PMC10210087 )?A chemical substance, either endogenuous, gut-microbiota derived, or exogenous, that accumulates in people with chronic kidney disease and causes adverse effects in the body.
antioxidant (PMC9774737 )?
biomarker (PMC11832355 , PMC11173766 )?
sulfur-containing amino acid (PMC5963642 )?

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
GC-MS	GC-MS Spectrum	splash10-004i-0920000000-20fbffbe76510c066e6f	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	splash10-0006-9000000000-1f800d28bca4b2b7a49f	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-014l-4900000000-c50d79ba3a5013bcf29f	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-000i-9000000000-025c9e1f4fb58138c43b	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-014i-4900000000-33f205e002f49f034764	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-052r-0900000000-c1f98c8182b5ddc09cb1	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-00ko-9800000000-80a1c80328e8836233a4	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0006-9100000000-1f611da44349ffdfaefe	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0bvi-9000000000-c9d62a66522e46a17f56	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-001i-3900000000-e8322d5858cba16a3bd2	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-00lr-6900000000-e0190a1cc33e605bac0a	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-001i-9000000000-900bb5d8fb11bec02e39	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-001i-0900000000-38e427e24202b2411597	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-001i-7900000000-5cf2133d9faac56032d3	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-001i-9000000000-942ac689538269d6ca7b	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0006-9000000000-166428542631f9ac0714	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0a4i-9000000000-9bcb57b924579a6c3411	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0a4j-9000000000-8eee886864db64f3eec2	Not Available	View Spectrum
1D NMR	¹H NMR Spectrum (1D, D₂O, predicted)	Not Available	Not Available	View Spectrum
1D NMR	¹³C NMR Spectrum (1D, D₂O, predicted)	Not Available	Not Available	View Spectrum

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
2033.0 Log mg/kg [1100:3600]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Description	Reference
hypertension	Associated With?	increase	A disorder characterized by a pathological increase in blood pressure; a repeatedly elevation in the blood pressure exceeding 140 over 90 mm Hg. (NCI CTCAE)	PMC8031033
hypertension	Associated With?	Not Available	A disorder characterized by a pathological increase in blood pressure; a repeatedly elevation in the blood pressure exceeding 140 over 90 mm Hg. (NCI CTCAE)	PMC3460365
inflammation	Associated With?	increase	Not Available	PMC7337253 , PMC12691759
inflammation	Associated With?	Not Available	Not Available	PMC13066785
cancer	Associated With?	increase	Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.	PMC8638980
cancer	Elevated in Blood In	increase	Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. There are over 100 types of cancers affect humans. The risk of developing certain cancers can be reduced by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat and avoiding too much sunlight exposure. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy and targeted therapy. The majority of cancers, some 90–95% of cases, are due to genetic mutations from environmental and lifestyle factors. The remaining 5–10% are due to inherited genetics.	PMC10385089
Alzheimer's disease	Associated With?	increase	A neurodegenerative disease which causes neural atrophy, leading to dementia and memory loss.	PMC9414574 , PMC12652985
Alzheimer's disease	Elevated in Blood In	increase	A neurodegenerative disease which causes neural atrophy, leading to dementia and memory loss.	PMC12331690
Alzheimer's disease	Associated With?	Not Available	A neurodegenerative disease which causes neural atrophy, leading to dementia and memory loss.	PMC11367486 , PMC10305463
dementia	Associated With?	increase	A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior. (DO)	PMC8868221
dementia	Associated With?	Not Available	A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior. (DO)	PMC3506942
anemia	Associated With?	increase	A disorder characterized by a reduction in the amount of hemoglobin in 100 ml of blood. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability. (NCI CTCAE)	PMC12328183
anemia	Associated With?	Not Available	A disorder characterized by a reduction in the amount of hemoglobin in 100 ml of blood. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability. (NCI CTCAE)	PMC10305463
type 2 diabetes mellitus	Associated With?	increase	Not Available	PMC7230842
osteoporosis	Is Biomarker Of	Not Available	A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. (NCI CTCAE)	PMC6372817
osteoporosis	Associated With?	increase	A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. (NCI CTCAE)	PMC10049198 , PMC12777449
diabetes mellitus	Associated With?	Not Available	A glucose metabolism disease characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. (DO)	PMC4698376
ischemic stroke	Associated With?	increase	Not Available	PMC3730376
ischemic stroke	Associated With?	Not Available	Not Available	PMC10094154 , PMC11367486
ischemic stroke	Elevated in Blood In	Not Available	Not Available	PMC10094154
stroke	Associated With?	increase	Not Available	PMC10051181 , PMC12088975
stroke	Elevated in Blood In	increase	Not Available	PMC5020564 , PMC10094154
stroke	Associated With?	Not Available	Not Available	PMC11679562
stroke	Elevated in Blood In	Not Available	Not Available	PMC8638980
chronic pain	Associated With?	positive	A state in which pain lasts for several weeks or months and may increase in severity.	PMC9012384
schizophrenia	Associated With?	Not Available	A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness. (DO)	PMC10305463
obesity	Associated With?	increase	A disorder characterized by having a high amount of body fat. (NCI CTCAE)	PMC12564886
atherosclerosis	Associated With?	increase	A disorder involving build-up of fatty material and calcium deposition in the arterial wall. It results in partial or complete occlusion of the arterial lumen.	PMC10051181 , PMC10049198
atherosclerosis	Associated With?	Not Available	A disorder involving build-up of fatty material and calcium deposition in the arterial wall. It results in partial or complete occlusion of the arterial lumen.	PMC5020564 , PMC11413206
atherosclerosis	Elevated in Blood In	Not Available	A disorder involving build-up of fatty material and calcium deposition in the arterial wall. It results in partial or complete occlusion of the arterial lumen.	PMC8638980
hypothyroidism	Associated With?	Not Available	Not Available	PMC8226782
cardiomyopathy	Associated With?	Not Available	A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle. (DO)	PMC10305463
myocardial infarction	Associated With?	increase	A disorder characterized by gross necrosis of the myocardium; this is due to an interruption of blood supply to the area. (NCI CTCAE)	PMC3426376
cognitive impairment	Associated With?	increase	Not Available	PMC12691759
cognitive impairment	Associated With?	Not Available	Not Available	PMC11679562 , PMC13315451
heart disease	Associated With?	Not Available	A cardiovascular system disease that involves the heart. (DO)	PMC11679562
heart disease	Elevated in Blood In	increase	A cardiovascular system disease that involves the heart. (DO)	PMC6396770
placental abruption	Associated With?	increase	Not Available	PMC11660019
placental abruption	Elevated in Urine In	Not Available	Not Available	PMC9146532
neuropathy	Associated With?	Not Available	A nervous system disease that is located in nerves or nerve cells. (do).	PMC8226782
thrombosis	Associated With?	increase	A formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.	PMC3460365 , PMC7230842
disease	Associated With?	Not Available	Not Available	PMC8179020
miscarriage	Elevated in Blood In	increase	A natural death of an embryo or fetus before it is able to survive independently.	PMC13409969
miscarriage	Associated With?	increase	A natural death of an embryo or fetus before it is able to survive independently.	PMC12396911
epilepsy	Associated With?	Not Available	A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions. (DO)	PMC11367486
Parkinson's disease	Associated With?	Not Available	A long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms generally come on slowly over time.	PMC11367486
vascular disease	Associated With?	Not Available	A cardiovascular system disease that primarily affects the blood vessels which includes the arteries, veins and capillaries that carry blood to and from the heart. (DO)	PMC3834880
vascular disease	Elevated in Blood In	increase	A cardiovascular system disease that primarily affects the blood vessels which includes the arteries, veins and capillaries that carry blood to and from the heart. (DO)	PMC10385089
neurodegenerative disease	Associated With?	Not Available	A central nervous system disease that results in the progressive deterioration of function or structure of neurons. (DO)	PMC12027286
kidney failure	Associated With?	Not Available	Not Available	PMC8226782
peripheral vascular disease	Associated With?	Not Available	A vascular disease that is characterized by obstruction of larger arteries not within the coronary, aortic arch vasculature, or brain. (DO)	PMC11679562
Toxic encephalopathy	Associated With?	Not Available	Not Available	PMC9886801
Toxic encephalopathy	Associated With?	increase	Not Available	PMC12691759
brain edema	Associated With?	increase	Not Available	PMC9886801
Congenital heart disease	Associated With?	increase	Not Available	PMC6210579
migraine	Associated With?	increase	A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing. (DO)	PMC12255647
migraine	Elevated in Blood In	increase	A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing. (DO)	PMC3444221
migraine	Associated With?	Not Available	A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing. (DO)	PMC10008946
vitamin B12 deficiency	Elevated in Blood In	increase	A vitamin metabolic disorder that results from low blood levels of vitamin B12. (DO)	PMC3834880
vitamin B12 deficiency	Is Biomarker Of	Not Available	A vitamin metabolic disorder that results from low blood levels of vitamin B12. (DO)	PMC8419074
brain disease	Associated With?	Not Available	Not Available	PMC10305463
pulmonary hypertension	Associated With?	Not Available	Not Available	PMC10305463
hepatic fibrosis	Associated With?	Not Available	Not Available	PMC13066785
vascular dementia	Associated With?	increase	Not Available	PMC9414574
post-traumatic stress disorder	Elevated in Blood In	increase	Not Available	PMC6930747
vitiligo	Associated With?	Not Available	A hypersensitivity reaction type II disease that causes depigmentation of patches of skin resulting from loss of function or death of melanoctyes. (DO)	PMC10590312
Cell Death	Associated With?	decrease	Not Available	PMC6787199
Oxidative Stress	Associated With?	Not Available	Not Available	PMC11832355 , PMC7761442
Oxidative Stress	Associated With?	increase	Not Available	PMC5016891 , PMC11275227
cardiovascular disorder	Associated With?	Not Available	Not Available	PMC7288538 , PMC7288538
cardiovascular disorder	Associated With?	increase	Not Available	PMC3460365 , PMC6342530
cardiovascular disorder	Elevated in Blood In	Not Available	Not Available	PMC8638980
Fetal Death	Associated With?	increase	Not Available	PMC11660019
Endoplasmic Reticulum Stress	Associated With?	decrease	Not Available	PMC9886801
DNA Damage	Associated With?	Not Available	Not Available	PMC9886801 , PMC7337253
nervous system disorder	Associated With?	increase	Not Available	PMC12027286
metabolic disease	Associated With?	increase	Not Available	PMC8638980
Deep venous thrombosis	Associated With?	increase	Not Available	PMC12396911
depressive disorder	Associated With?	Not Available	Not Available	PMC3506942
Premature birth	Associated With?	Not Available	Not Available	PMC7278868
Premature birth	Associated With?	increase	Not Available	PMC12396911
Genomic Instability	Associated With?	increase	Not Available	PMC8638980
Congenital Abnormalities	Associated With?	increase	Not Available	PMC6210579
Congenital Abnormalities	Associated With?	Not Available	Not Available	PMC4698376
hypertension, pregnancy-induced	Associated With?	increase	Not Available	PMC12396911
Neurodegeneration	Associated With?	Not Available	Not Available	PMC9886801 , PMC9886801
Mental deterioration	Associated With?	increase	Not Available	PMC7337253
Mental deterioration	Associated With?	Not Available	Not Available	PMC9414574 , PMC9414574
Sarcopenia	Associated With?	Not Available	Not Available	PMC8226782 , PMC8226782
Neurodegenerative Diseases	Associated With?	Not Available	Not Available	PMC4698376
hyperlipidemia	Associated With?	increase	Not Available	PMC5016891
Thromboembolism	Associated With?	Not Available	Not Available	PMC10305463
Mutation	Associated With?	increase	Not Available	PMC8638980
peripheral arterial disease	Associated With?	increase	Not Available	PMC3426376
cognitive disorder	Associated With?	Not Available	Not Available	PMC3834880
Brain atrophy	Associated With?	Not Available	Not Available	PMC9414574 , PMC9414574
hyperhomocysteinemia	Associated With?	Not Available	Not Available	PMC7414014 , PMC7761442
hyperhomocysteinemia	Elevated in Blood In	Not Available	Not Available	PMC12691759 , PMC13315451
hyperhomocysteinemia	Elevated in Blood In	increase	Not Available	PMC5020564
chronic renal failure syndrome	Elevated in Blood In	Not Available	Not Available	PMC5020564
homocystinuria	Is Biomarker Of	Not Available	Not Available	PMC9544878
homocystinuria	Associated With?	Not Available	Not Available	PMC11355204 , PMC11482134
homocystinuria due to methylene tetrahydrofolate reductase deficiency	Elevated in Blood In	increase	Not Available	PMC3460365
autosomal recessive disease	Elevated in Blood In	increase	Not Available	PMC11355204
Decreased circulating folate concentration	Associated With?	Not Available	Not Available	PMC3527168 , PMC8226782
Decreased circulating folate concentration	Is Biomarker Of	Not Available	Not Available	PMC6701563
carotid stenosis	Elevated in Blood In	increase	Not Available	PMC5020564
Neurofibrillary tangles	Associated With?	Not Available	Not Available	PMC9414574
musculoskeletal system disorder	Associated With?	Not Available	Not Available	PMC11659002
acatalasia	Elevated in Blood In	increase	Not Available	PMC3016327
Folic Acid Deficiency	Is Biomarker Of	Not Available	Not Available	PMC3834880
hemolytic-uremic syndrome	Associated With?	Not Available	Not Available	PMC10305463

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000010	Insecticides?Insecticides are synthetic chemicals designed to control or eliminate insect pests that threaten crops and other agricultural products.	Agriculture & land management	PubChem
CEDs000070	Stormwater runoff?Stormwater runoff refers to the flow of rainwater or melted snow that does not soak into the ground and instead collects pollutants as it travels over impervious surfaces such as roads and parking lots.	Automotive & urban infrastructure	PubChem
CEDs000233	Brushes?Brushes used in personal care and cosmetics can be a source of synthetic chemical contamination due to the materials and coatings used in their manufacturing.	Personal care & cosmetics	PubChem
CEDs000506	Antennas?Antennas, commonly used in communication technologies, can be a source of synthetic chemical contamination through the materials and coatings used in their construction.	Electrical & Electronic Equipment	PubChem
CEDs000511	Conductors Or Conductive Bodies Characterised By The Conductive Materials?Conductors, or conductive bodies, are materials that allow the flow of electrical current, typically made from metals such as copper, aluminum, or silver.	Electrical & Electronic Equipment	PubChem
CEDs000518	Electrically Stimulated Smoking Devices?Electrically stimulated smoking devices, commonly known as e-cigarettes or vape pens, utilize electrical components to heat a liquid solution, often containing nicotine, flavorings, and other additives, to produce an aerosol for inhalation.	Electrical & Electronic Equipment	PubChem
CEDs000519	Electrodes?Electrodes, used in various electrical and electronic applications, can be a source of synthetic chemical contamination due to the materials from which they are constructed and the processes involved in their manufacturing.	Electrical & Electronic Equipment	PubChem
CEDs000524	Hybrid Capacitors?Hybrid capacitors are energy storage devices that combine the properties of electrolytic and supercapacitors, utilizing a combination of electrochemical principles to achieve higher energy density and power density.	Electrical & Electronic Equipment	PubChem
CEDs000544	Fermentation Processes For Beer?Fermentation processes for beer involve the conversion of sugars into alcohol and carbon dioxide by yeast.	Food, food processing & cookware	PubChem
CEDs000545	Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.	Food, food processing & cookware	PubChem
CEDs000555	Bleaching Agents?Bleaching agents are chemical substances used to whiten or lighten materials, often employed in various cleaning products for their stain removal and disinfecting properties.	Household cleaning & consumer products	PubChem
CEDs000556	Cigar Cigarettes?Cigar cigarettes are a source of synthetic chemical contamination due to the combustion of various tobacco blends and additives.	Household cleaning & consumer products	PubChem
CEDs000561	Perfumes Within Detergents And Soaps?Perfumes within detergents and soaps are synthetic fragrance compounds added to enhance the sensory experience of cleaning products.	Household cleaning & consumer products	PubChem
CEDs000563	Soap Detergents?Soap detergents are synthetic surfactants designed to enhance the cleaning efficacy of water by reducing surface tension, allowing for better interaction with dirt and grease.	Household cleaning & consumer products	PubChem
CEDs000569	Tobacco Smoke Filters?Tobacco smoke filters are designed to reduce the inhalation of harmful substances in cigarette smoke, including tar and other particulate matter.	Household cleaning & consumer products	PubChem
CEDs000580	Manufacture Preparation Of Tobacco Products?The manufacture and preparation of tobacco products involve various processes that can result in the introduction of synthetic chemicals into the environment.	Industrial manufacturing & chemical processing	PubChem
CEDs000600	Herbicides And Algicides?Herbicides and algicides are synthetic chemicals primarily used to control unwanted plants and algae in various environments.	Agriculture & land management	PubChem
CEDs000603	Nematocides?Nematocides are synthetic chemicals specifically designed to control nematodes, which are microscopic roundworms that can cause significant damage to crops and plants.	Agriculture & land management	PubChem
CEDs000605	Pest Repellants?Pest repellents, often formulated from synthetic chemicals, are widely used to protect crops from insect infestations and other pests.	Agriculture & land management	PubChem
CEDs000606	Plant Growth Regulators?Plant Growth Regulators (PGRs) are synthetic chemicals designed to influence the growth and development of plants.	Agriculture & land management	PubChem
CEDs000609	Aftershave?Aftershave is a grooming product typically used to soothe and protect the skin following shaving.	Personal care & cosmetics	PubChem
CEDs000610	Aftersun Products?Aftersun products are designed to soothe and hydrate the skin after sun exposure, often containing various synthetic chemicals such as emollients, preservatives, and fragrances.	Personal care & cosmetics	PubChem
CEDs000611	Anti Perspirants Or Body Deoderants?Antiperspirants and body deodorants commonly contain synthetic chemicals such as aluminum compounds, parabens, and synthetic fragrances.	Personal care & cosmetics	PubChem
CEDs000613	Depilatories?Depilatories are products designed to remove unwanted hair through the application of synthetic chemicals that break down the protein structure of hair, facilitating its removal.	Personal care & cosmetics	PubChem
CEDs000614	Essential Oils Or Perfumes?Essential oils and perfumes are complex mixtures of volatile compounds derived from natural or synthetic sources, commonly used for their aromatic properties.	Personal care & cosmetics	PubChem
CEDs000615	Eye Makeup Products?Eye makeup products, including mascaras, eyeliners, and eyeshadows, often contain a variety of synthetic chemicals such as pigments, preservatives, and film-forming agents.	Personal care & cosmetics	PubChem
CEDs000617	Lip Care Products?Lip care products, including lipsticks, balms, and glosses, often contain a variety of synthetic chemicals such as parabens, phthalates, and synthetic fragrances.	Personal care & cosmetics	PubChem
CEDs000618	Lip Makeup Products?Lip makeup products, such as lipsticks, lip glosses, and lip liners, often contain a variety of synthetic chemicals, including pigments, preservatives, and emollients.	Personal care & cosmetics	PubChem
CEDs000632	Apparel?Apparel production often involves the use of various synthetic chemicals, including dyes, finishing agents, and preservatives.	Textiles, leather & furnishings	PubChem
CEDs000642	Footwear?Footwear production often involves the use of various synthetic chemicals, such as adhesives, dyes, and treatments, which can contribute to environmental contamination.	Textiles, leather & furnishings	PubChem
CEDs000662	Yarns Or Threads?Yarns or threads used in textiles can be a source of synthetic chemical contamination due to the production processes and treatments they undergo.	Textiles, leather & furnishings	PubChem
CEDs000671	Airplanes And Helicopters?Airplanes and helicopters are significant sources of synthetic chemical contamination primarily through the use of aviation fuels, lubricants, and de-icing agents.	Aviation & Aerospace	PubChem
CEDs000678	Nitrogenous Fertilisers?Nitrogenous fertilizers are synthetic chemical compounds primarily used to enhance plant growth by supplying essential nitrogen, a crucial nutrient for photosynthesis and protein synthesis.	Agriculture & land management	PubChem
CEDs000679	Phosphatic Fertilisers?Phosphatic fertilizers are synthetic chemical products primarily composed of phosphorus, which is essential for plant growth.	Agriculture & land management	PubChem
CEDs000684	Cements?Cements are a composite material primarily used as a binding agent in construction applications, formed by the calcination of limestone and clay minerals at high temperatures.	Building & Construction	PubChem
CEDs000685	Ceramics?Ceramics can be a source of synthetic chemical contamination through various additives and processing agents used in their production.	Building & Construction	PubChem
CEDs000696	Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.	Industrial manufacturing & chemical processing	PubChem
CEDs000698	Jewellery?Jewellery production often involves the use of various synthetic chemicals during the extraction and processing of metals.	Mining & metal processing	PubChem
CEDs000730	Contact Lens Cases?Contact lens cases are small containers designed to store contact lenses in a sterile environment, typically made from various synthetic materials including plastics such as polypropylene or polycarbonate.	Healthcare, pharmaceuticals & veterinary products	PubChem
CEDs000734	Coating Compositions?Coating compositions, which include paints, sealants, and varnishes, are formulated with a variety of synthetic chemicals such as solvents, resins, pigments, and additives.	Building & Construction	PubChem
CEDs000735	Explosives?Explosives are chemical compounds or mixtures designed to undergo rapid decomposition, releasing energy in the form of gas and heat.	Defense & military infrastructure	PubChem
CEDs000738	Cooling Circuit Water?Cooling circuit water is utilized in various industrial processes to absorb and dissipate heat generated during operations.	Industrial manufacturing & chemical processing	PubChem
CEDs000739	Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.	Paper, pulp & fiber products	PubChem
CEDs000740	Paper?Paper production involves the processing of wood fibers and the use of various chemicals, which can lead to synthetic chemical contamination.	Paper, pulp & fiber products	PubChem
CEDs000741	Pigment Pastes?Pigment pastes are concentrated dispersions of pigments used to impart color and properties to materials.	Paper, pulp & fiber products	PubChem
CEDs000742	Leather Tanning?Leather tanning is a process that transforms raw animal hides into durable leather through the application of various chemicals, including chromium salts, aldehydes, and vegetable tannins.	Textiles, leather & furnishings	PubChem
CEDs000743	Sludge Treatment?Sludge treatment involves the processing of waste materials generated from wastewater treatment plants, which often contain a variety of organic and inorganic substances.	Wastewater, sanitation & biosolids	PubChem
CEDs000744	Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.	Wastewater, sanitation & biosolids	PubChem
CEDs01223	Green Tea	Food, food processing & cookware	PMC12192211
CEDs02255	Water	Aquatic systems & sediments	PMC4976779
CEDs02459	Artificial Seawater	Aquatic systems & sediments	PMC10700628

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Cystathionine beta-synthase	P35520	Humans	Known	Not Available
Click to view 3D structure	Metabotropic glutamate receptor 8	P47743	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.533 Applicability Domain 0.565 Statistical Significance 2.00e-05 Supporting Reference Compounds 2 E-value 0.155698
Click to view 3D structure	Asc-type amino acid transporter 1	P63116	Rat	Predicted (SEA)	Prediction Confidence Score 0.5 Applicability Domain 0.5 Statistical Significance 2.00e-05 Supporting Reference Compounds 2 E-value 0.155698
Click to view 3D structure	Metabotropic glutamate receptor 6	P35349	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.492 Applicability Domain 0.565 Statistical Significance 6.00e-05 Supporting Reference Compounds 24 E-value 0.467095
Click to view 3D structure	Metabotropic glutamate receptor 4	P31423	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.468 Applicability Domain 0.565 Statistical Significance 2.00e-04 Supporting Reference Compounds 38 E-value 1.55698
Click to view 3D structure	Metabotropic glutamate receptor 2	P31421	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.468 Applicability Domain 0.565 Statistical Significance 2.30e-04 Supporting Reference Compounds 53 E-value 1.79053
Click to view 3D structure	Arginase	Q8I384	Plasmodium falciparum	Predicted (SEA)	Prediction Confidence Score 0.464 Applicability Domain 0.464 Statistical Significance 6.00e-05 Supporting Reference Compounds 1 E-value 0.467095
Click to view 3D structure	Metabotropic glutamate receptor 6	O15303	Humans	Predicted (SEA)	Prediction Confidence Score 0.455 Applicability Domain 0.565 Statistical Significance 1.40e-04 Supporting Reference Compounds 39 E-value 1.08989
Click to view 3D structure	Metabotropic glutamate receptor 4	Q14833	Humans	Predicted (SEA)	Prediction Confidence Score 0.448 Applicability Domain 0.565 Statistical Significance 6.00e-04 Supporting Reference Compounds 69 E-value 4.67095
Click to view 3D structure	Metabotropic glutamate receptor 8	P70579	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.443 Applicability Domain 0.565 Statistical Significance 9.00e-05 Supporting Reference Compounds 28 E-value 0.700643
Click to view 3D structure	Excitatory amino acid transporter 3	P43005	Humans	Predicted (SEA)	Prediction Confidence Score 0.432 Applicability Domain 0.565 Statistical Significance 1.60e-04 Supporting Reference Compounds 13 E-value 1.24559
Click to view 3D structure	Metabotropic glutamate receptor 8	O00222	Humans	Predicted (SEA)	Prediction Confidence Score 0.427 Applicability Domain 0.565 Statistical Significance 1.70e-04 Supporting Reference Compounds 48 E-value 1.32344
Click to view 3D structure	Glutamate receptor ionotropic, kainate 1	P22756	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.421 Applicability Domain 0.565 Statistical Significance 2.00e-04 Supporting Reference Compounds 45 E-value 1.55698
Click to view 3D structure	Methionine synthase	P13009	Escherichia coli (strain K12)	Known	Not Available
Click to view 3D structure	Glutamine synthetase	P0A9C5	Escherichia coli K-12	Predicted (SEA)	Prediction Confidence Score 0.419 Applicability Domain 0.419 Statistical Significance 4.00e-05 Supporting Reference Compounds 1 E-value 0.311397
Click to view 3D structure	S-methylmethionine--homocysteine S-methyltransferase BHMT2	Q9H2M3	Humans	Predicted (SEA)	Prediction Confidence Score 0.419 Applicability Domain 0.419 Statistical Significance 5.00e-05 Supporting Reference Compounds 1 E-value 0.389246
Click to view 3D structure	Glutamate receptor ionotropic, kainate 1	P39086	Humans	Predicted (SEA)	Prediction Confidence Score 0.419 Applicability Domain 0.565 Statistical Significance 1.10e-04 Supporting Reference Compounds 31 E-value 0.856341
Click to view 3D structure	Arginase-2, mitochondrial	P78540	Humans	Predicted (SEA)	Prediction Confidence Score 0.414 Applicability Domain 0.464 Statistical Significance 4.00e-05 Supporting Reference Compounds 7 E-value 0.311397
Click to view 3D structure	Glutamate receptor ionotropic, kainate 3	P42264	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.41 Applicability Domain 0.565 Statistical Significance 1.80e-04 Supporting Reference Compounds 26 E-value 1.40129
Click to view 3D structure	Glutamate receptor ionotropic, kainate 2	P42260	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.41 Applicability Domain 0.565 Statistical Significance 1.50e-04 Supporting Reference Compounds 18 E-value 1.16774
Click to view 3D structure	Metabotropic glutamate receptor 2	Q14416	Humans	Predicted (SEA)	Prediction Confidence Score 0.409 Applicability Domain 0.565 Statistical Significance 7.00e-04 Supporting Reference Compounds 85 E-value 5.44945
Click to view 3D structure	Betaine--homocysteine S-methyltransferase 1	Q93088	Humans	Predicted (SEA)	Prediction Confidence Score 0.406 Applicability Domain 0.406 Statistical Significance 6.00e-05 Supporting Reference Compounds 1 E-value 0.467095
Click to view 3D structure	Glutamate transporter homolog	O59010	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 /NBRC 100139 / OT-3)	Predicted (SEA)	Prediction Confidence Score 0.4 Applicability Domain 0.478 Statistical Significance 5.00e-05 Supporting Reference Compounds 3 E-value 0.389246
Click to view 3D structure	Metabotropic glutamate receptor 1	Q13255	Humans	Predicted (SEA)	Prediction Confidence Score 0.39 Applicability Domain 0.565 Statistical Significance 5.60e-04 Supporting Reference Compounds 68 E-value 4.35956
Click to view 3D structure	Glutamate receptor ionotropic, kainate 2	Q13002	Humans	Predicted (SEA)	Prediction Confidence Score 0.389 Applicability Domain 0.565 Statistical Significance 1.10e-04 Supporting Reference Compounds 16 E-value 0.856341
Click to view 3D structure	Metabotropic glutamate receptor 1	P23385	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.384 Applicability Domain 0.565 Statistical Significance 4.90e-04 Supporting Reference Compounds 45 E-value 3.81461
Click to view 3D structure	Glutamate receptor 4	P48058	Humans	Predicted (SEA)	Prediction Confidence Score 0.384 Applicability Domain 0.565 Statistical Significance 1.10e-04 Supporting Reference Compounds 25 E-value 0.856341
Click to view 3D structure	3-mercaptopyruvate sulfurtransferase	P25325	Humans	Known	Not Available
Click to view 3D structure	Albumin	P02768	Humans	Known	Not Available
Click to view 3D structure	Methylenetetrahydrofolate reductase (NADPH)	P42898	Humans	Known	Not Available