4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-a,a-diphenylpiperidine-1-butyramide monohydrochloride (CED0076819)

Record Information

Version

1.0

Creation Date

2026-04-05 22:00:07 UTC

Update Date

2026-04-05 22:00:07 UTC

Accession Number

CHEM110336

Identification

Common Name

4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-a,a-diphenylpiperidine-1-butyramide monohydrochloride

Class

Small Molecule

Description

4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-a,a-diphenylpiperidine-1-butyramide monohydrochloride belongs to the diphenylmethanes, a subclass of benzene and substituted derivatives within the organic compounds. This compound is characterized by the chemical formula C29H34Cl2N2O2. It has been identified in or released from 12 recorded sources. Within the building and construction sector, it is associated with ceilings, fencing, floors, ladders, and roofs, among four additional sources. Additionally, it is found in electrical and electronic equipment, specifically in antennas, amplifiers, and adjustable resistors.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₂₉H₃₄Cl₂N₂O₂

Average Molecular Mass

Not Available

Monoisotopic Mass

512.200 g/mol

CAS Registry Number

Not Available

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

Not Available

InChI Identifier

InChI=1/C29H33ClN2O2.ClH/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23;/h3-16,34H,17-22H2,1-2H3;1H

InChI Key

PGYPOBZJRVSMDS-UHFFFAOYSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Toxicity Values

Toxicity Value	Unit	Value Range	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Reference
255.0	Log mg/kg	[140:450]	Rat	LD50	oral	predicted	Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
495	Ceilings	Building & Construction	Not Available
496	Fencing	Building & Construction	Not Available
497	Floors	Building & Construction	Not Available
498	Ladders	Building & Construction	Not Available
499	Roofs	Building & Construction	Not Available
500	Stairs And Ramps	Building & Construction	Not Available
501	Sunshades Awnings Or Outside Screens	Building & Construction	Not Available
502	Sunshades Awnings Or Outside Screens	Building & Construction	Not Available
503	Tents Or Canopies	Building & Construction	Not Available
504	Adjustable Resistors	Electrical & Electronic Equipment	Not Available
505	Amplifiers	Electrical & Electronic Equipment	Not Available
506	Antennas	Electrical & Electronic Equipment	Not Available

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Mu-type opioid receptor	P35372	Humans	Predicted (SEA)	2.25763
Click to view 3D structure	D(4) dopamine receptor	P21917	Humans	Predicted (SEA)	1.01204
Click to view 3D structure	Sodium-dependent serotonin transporter	P31645	Humans	Predicted (SEA)	0.700643
Click to view 3D structure	5-hydroxytryptamine receptor 2B	P41595	Humans	Predicted (SEA)	2.33548
Click to view 3D structure	Sigma non-opioid intracellular receptor 1	Q99720	Humans	Predicted (SEA)	2.80257
Click to view 3D structure	Kappa-type opioid receptor	P41145	Humans	Predicted (SEA)	20.7857
Click to view 3D structure	Delta-type opioid receptor	P41143	Humans	Predicted (SEA)	22.4206
Click to view 3D structure	Alpha-2A adrenergic receptor	P08913	Humans	Predicted (SEA)	3.81461
Click to view 3D structure	Histamine H2 receptor	P25021	Humans	Predicted (SEA)	1.86838
Click to view 3D structure	D(2) dopamine receptor	P14416	Humans	Predicted (SEA)	29.1935
Click to view 3D structure	D(3) dopamine receptor	P35462	Humans	Predicted (SEA)	21.0971
Click to view 3D structure	Voltage-gated inwardly rectifying potassium channel KCNH2	Q12809	Humans	Predicted (SEA)	23.1991
Click to view 3D structure	Beta-2 adrenergic receptor	P07550	Humans	Predicted (SEA)	3.89246
Click to view 3D structure	Sodium-dependent dopamine transporter	Q01959	Humans	Predicted (SEA)	10.5096
Click to view 3D structure	Sodium channel protein type 5 subunit alpha	Q14524	Humans	Predicted (SEA)	17.4382
Click to view 3D structure	Alpha-1A adrenergic receptor	P35348	Humans	Predicted (SEA)	19.8516
Click to view 3D structure	Sigma intracellular receptor 2	Q5BJF2	Humans	Predicted (SEA)	7.31783
Click to view 3D structure	Histamine H1 receptor	P35367	Humans	Predicted (SEA)	22.0313
Click to view 3D structure	Cytochrome P450 2D6	P10635	Humans	Predicted (SEA)	33.1638
Click to view 3D structure	5-hydroxytryptamine receptor 1D	P28221	Humans	Predicted (SEA)	15.6477
Click to view 3D structure	Alpha-2B adrenergic receptor	P18089	Humans	Predicted (SEA)	12.6116
Click to view 3D structure	Alpha-1B adrenergic receptor	P15823	Rattus norvegicus	Predicted (SEA)	4.5931
Click to view 3D structure	ATP-dependent translocase ABCB1	P08183	Humans	Predicted (SEA)	5.99439
Click to view 3D structure	Alpha-1A adrenergic receptor	P43140	Rattus norvegicus	Predicted (SEA)	19.2288
Click to view 3D structure	Alpha-1B adrenergic receptor	P35368	Humans	Predicted (SEA)	23.1991