(1E)-1,2,3,3,3-Pentafluoro-1-(trifluoromethoxy)prop-1-ene (CED0077333)

Record Information
Version1.0
Creation Date2026-04-06 05:58:29 UTC
Update Date2026-08-22 15:16:02 UTC
Accession NumberCHEM118529
Identification
Common Name(1E)-1,2,3,3,3-Pentafluoro-1-(trifluoromethoxy)prop-1-ene
ClassSmall Molecule
Description
(1E)-1,2,3,3,3-Pentafluoro-1-(trifluoromethoxy)prop-1-ene belongs to the halomethanes, a subclass of alkyl halides within the organic compounds. This organohalogen compound has the chemical formula C4F8O and an average molecular weight of 216.03 g/mol. The compound is found in or released from 13 recorded sources across multiple sectors. Within the energy, oil & gas and industrial manufacturing & chemical processing sectors, it is utilized in lubricants. It is present in healthcare, pharmaceuticals & veterinary products via medical devices, and in food, food processing & cookware through food packaging. It is also found in textiles, leather & furnishings, specifically in carpets, rugs, and synthetic textiles. Additionally, it is associated with electrical & electronic equipment, including batteries, capacitors, printed circuit boards, cell phones, wires and cables, and one other source. Recorded routes of exposure for this substance include inhalation, oral, and touch.
Contaminant Type
  • PFAS
Chemical Structure
SynonymsNot Available
Chemical FormulaC4F8O
Average Molecular Mass216.030 g/mol
Monoisotopic Mass215.982 g/mol
CAS Registry Number1621181-80-3
IUPAC NameNot Available
Traditional NameNot Available
SMILESFC(OC(F)(F)F)=C(F)C(F)(F)F
InChI IdentifierInChI=1S/C4F8O/c5-1(3(7,8)9)2(6)13-4(10,11)12/b2-1-
InChI KeySYLBHDWIEFOPOP-UPHRSURJSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity Values
Toxicity ValueUnitValue RangeOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalReference
1730.0Log mg/kg[970:3100]RatLD50oralpredictedNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
7PesticidesAgriculture & land managementNot Available
120Wires and cablesElectrical & Electronic EquipmentNot Available
121Printed circuit boardsElectrical & Electronic EquipmentNot Available
125BatteriesElectrical & Electronic EquipmentNot Available
130SemiconductorsElectrical & Electronic EquipmentNot Available
138LubricantsEnergy, oil & gasNot Available
147Food packagingFood, food processing & cookwareNot Available
174LubricantsIndustrial manufacturing & chemical processingNot Available
234Medical devicesHealthcare, pharmaceuticals & veterinary productsNot Available
451Carpets and RugsTextiles, leather & furnishingsNot Available
454Synthetic textilesTextiles, leather & furnishingsNot Available
490Personal care & cosmeticsNot Available
492Cell phonesElectrical & Electronic EquipmentNot Available
493CapacitorsElectrical & Electronic EquipmentNot Available
Pathways
0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureCocaine esteraseO00748HumansPredicted (SEA)3669.5
Click to view 3D structureAcylcarnitine hydrolaseQ91WG0Mus musculusPredicted (SEA)99.2578
Click to view 3D structureFatty-acid amide hydrolase 1O00519HumansPredicted (SEA)7079.53
Bifunctional epoxide hydrolase 2 structureClick to view 3D structureBifunctional epoxide hydrolase 2P34913HumansPredicted (SEA)6869.34
Click to view 3D structureInward rectifier potassium channel 2P35561Mus musculusPredicted (SEA)2144.2
Click to view 3D structureCG8425-PA [Drosophila melanogaster]A1ZA98Drosophila melanogasterPredicted (SEA)113.193
Liver carboxylesterase 1 structureClick to view 3D structureLiver carboxylesterase 1P23141HumansPredicted (SEA)4363.45
Click to view 3D structureLiver carboxylesteraseQ29550Sus scrofaPredicted (SEA)2118.51
Click to view 3D structureJuvenile hormone esteraseQ9GPG0Manduca sextaPredicted (SEA)121.523
Click to view 3D structureBifunctional epoxide hydrolase 2P34914Mus musculusPredicted (SEA)5343.73
Click to view 3D structureSerum paraoxonase/arylesterase 2Q15165HumansPredicted (SEA)2102.32
Click to view 3D structureSerum paraoxonase/lactonase 3Q15166HumansPredicted (SEA)2102.32
Click to view 3D structureFatty-acid amide hydrolase 1P97612Rattus norvegicusPredicted (SEA)7306.23
RAF proto-oncogene serine/threonine-protein kinase structureClick to view 3D structureRAF proto-oncogene serine/threonine-protein kinaseP04049HumansPredicted (SEA)7685.43
Click to view 3D structureEsteraseA3QR02Chilo suppressalisPredicted (SEA)115.217
Click to view 3D structureFatty-acid amide hydrolase 1O08914Mus musculusPredicted (SEA)6985.49
Click to view 3D structureAcetylpolyamine amidohydrolaseQ48935Mycoplana ramosaPredicted (SEA)183.88
Acetylcholinesterase structureClick to view 3D structureAcetylcholinesteraseP22303HumansPredicted (SEA)7771.06
Click to view 3D structureLiver carboxylesterase B-1Q63010Rattus norvegicusPredicted (SEA)329.224
Click to view 3D structureArylacetamide deacetylaseP22760HumansPredicted (SEA)3311.63
Click to view 3D structureBifunctional epoxide hydrolase 2P80299Rattus norvegicusPredicted (SEA)7399.88
Click to view 3D structurePhosphoglycerate kinaseP00560Saccharomyces cerevisiae S288cPredicted (SEA)93.1077
Click to view 3D structureEpoxide hydrolase 1P07099HumansPredicted (SEA)6647.62
Voltage-gated inwardly rectifying potassium channel KCNH2 structureClick to view 3D structureVoltage-gated inwardly rectifying potassium channel KCNH2Q12809HumansPredicted (SEA)7782.74
Free fatty acid receptor 4 structureClick to view 3D structureFree fatty acid receptor 4Q5NUL3HumansPredicted (SEA)7743.19
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available