(2E)-1,1,1,4,4,5,5,6,6,6-Decafluorohex-2-ene (CED0137374)

Record Information
Version1.0
Creation Date2026-04-06 07:09:27 UTC
Update Date2026-09-01 09:29:04 UTC
Accession NumberCHEM119680
Identification
Common Name(2E)-1,1,1,4,4,5,5,6,6,6-Decafluorohex-2-ene
ClassSmall Molecule
Description
(2E)-1,1,1,4,4,5,5,6,6,6-Decafluorohex-2-ene belongs to the organofluorides, a class of organohalogen compounds within the organic compounds. This compound has the chemical formula C6H2F10 and an average molecular weight of 264.07 g/mol. The substance is found in or released from 13 recorded sources across multiple sectors. Within electrical and electronic equipment, it is associated with cell phones, capacitors, batteries, printed circuit boards, wires and cables, and one additional source. It is present in textiles, leather and furnishings, specifically in synthetic textiles as well as carpets and rugs. In the food, food processing and cookware sector, it is found in food packaging, while in healthcare, pharmaceuticals and veterinary products, it is linked to medical devices. Additionally, it is used as a lubricant within the energy, oil and gas sector as well as in industrial manufacturing and chemical processing. One other sector is also recorded as a source. Recorded exposure routes for this compound include inhalation, oral, and touch.
Contaminant Type
  • PFAS
Chemical Structure
SynonymsNot Available
Chemical FormulaC6H2F10
Average Molecular Mass264.066 g/mol
Monoisotopic Mass264.000 g/mol
CAS Registry Number83227-62-7
IUPAC NameNot Available
Traditional NameNot Available
SMILESFC(F)(F)C=CC(F)(F)C(F)(F)C(F)(F)F
InChI IdentifierInChI=1S/C6H2F10/c7-3(8,1-2-4(9,10)11)5(12,13)6(14,15)16/h1-2H/b2-1+
InChI KeyBRHMFXVXLONVKC-OWOJBTEDSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity Values
Toxicity ValueUnitValue RangeOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalReference
5757.0Log mg/kg[3200:10000]RatLD50oralpredictedNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
7PesticidesAgriculture & land managementNot Available
120Wires and cablesElectrical & Electronic EquipmentNot Available
121Printed circuit boardsElectrical & Electronic EquipmentNot Available
125BatteriesElectrical & Electronic EquipmentNot Available
130SemiconductorsElectrical & Electronic EquipmentNot Available
138LubricantsEnergy, oil & gasNot Available
147Food packagingFood, food processing & cookwareNot Available
174LubricantsIndustrial manufacturing & chemical processingNot Available
234Medical devicesHealthcare, pharmaceuticals & veterinary productsNot Available
451Carpets and RugsTextiles, leather & furnishingsNot Available
454Synthetic textilesTextiles, leather & furnishingsNot Available
490Personal care & cosmeticsNot Available
492Cell phonesElectrical & Electronic EquipmentNot Available
493CapacitorsElectrical & Electronic EquipmentNot Available
Pathways
0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Nuclear receptor ROR-gamma structureClick to view 3D structureNuclear receptor ROR-gammaP51449HumansPredicted (SEA)7732.84
Click to view 3D structureMalonyl-CoA decarboxylase, mitochondrialQ99J39Mus musculusPredicted (SEA)5269.54
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 structureClick to view 3D structureInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2O43314HumansPredicted (SEA)1082.88
Oxysterols receptor LXR-alpha structureClick to view 3D structureOxysterols receptor LXR-alphaQ13133HumansPredicted (SEA)7753.16
Click to view 3D structureEsteraseA3QR02Chilo suppressalisPredicted (SEA)559.58
Nuclear receptor ROR-alpha structureClick to view 3D structureNuclear receptor ROR-alphaP35398HumansPredicted (SEA)7712.99
Estrogen receptor structureClick to view 3D structureEstrogen receptorP03372HumansPredicted (SEA)7779.78
Click to view 3D structureNuclear receptor ROR-betaQ92753HumansPredicted (SEA)7711.9
Carbonic anhydrase 2 structureClick to view 3D structureCarbonic anhydrase 2P00918HumansPredicted (SEA)7783.99
Carbonic anhydrase 1 structureClick to view 3D structureCarbonic anhydrase 1P00915HumansPredicted (SEA)7783.68
Oxysterols receptor LXR-beta structureClick to view 3D structureOxysterols receptor LXR-betaP55055HumansPredicted (SEA)7759.31
Progesterone receptor structureClick to view 3D structureProgesterone receptorP06401HumansPredicted (SEA)7774.96
Estrogen receptor beta structureClick to view 3D structureEstrogen receptor betaQ92731HumansPredicted (SEA)7781.89
Interleukin-17F structureClick to view 3D structureInterleukin-17FQ96PD4HumansPredicted (SEA)5284.09
Malonyl-CoA decarboxylase, mitochondrial structureClick to view 3D structureMalonyl-CoA decarboxylase, mitochondrialO95822HumansPredicted (SEA)5512.04
Liver carboxylesterase 1 structureClick to view 3D structureLiver carboxylesterase 1P23141HumansPredicted (SEA)7698.9
Click to view 3D structureLiver carboxylesterase B-1Q63010Rattus norvegicusPredicted (SEA)1544.22
5-hydroxytryptamine receptor 2A structureClick to view 3D structure5-hydroxytryptamine receptor 2AP28223HumansPredicted (SEA)7784.3
5-hydroxytryptamine receptor 2C structureClick to view 3D structure5-hydroxytryptamine receptor 2CP28335HumansPredicted (SEA)7784.38
Nuclear receptor subfamily 1 group I member 2 structureClick to view 3D structureNuclear receptor subfamily 1 group I member 2O75469HumansPredicted (SEA)7782.04
Click to view 3D structureLiver carboxylesteraseQ29550Sus scrofaPredicted (SEA)7085.99
Glucocorticoid receptor structureClick to view 3D structureGlucocorticoid receptorP04150HumansPredicted (SEA)7780.64
Carbonic anhydrase 7 structureClick to view 3D structureCarbonic anhydrase 7P43166HumansPredicted (SEA)7783.6
5-hydroxytryptamine receptor 2B structureClick to view 3D structure5-hydroxytryptamine receptor 2BP41595HumansPredicted (SEA)7784.38
Click to view 3D structureANK_REP_REGION domain-containing proteinH0VJD1Cavia porcellusPredicted (SEA)4887.69
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available