16-Hydroxytestosterone (CED0031276)

Record Information

Version

1.0

Creation Date

2026-04-06 09:02:47 UTC

Update Date

2026-05-21 09:05:01 UTC

SynCED ID

CED0031276

Secondary Accession Numbers

CHEM121034

Identification

Common Name

16-Hydroxytestosterone

Class

Small Molecule

Description

16-Hydroxytestosterone belongs to the androstane steroids, a subclass of steroids and steroid derivatives within the organic compounds. This compound is categorized under the superclass of lipids and lipid-like molecules. It has been identified in or released from 13 recorded sources across several sectors. Within electrical and electronic equipment, it is found in capacitors, batteries, printed circuit boards, wires and cables, cell phones, and one additional source. In the textiles, leather and furnishings sector, it is associated with carpets, rugs, and synthetic textiles. Its presence is also noted in food packaging within the food, food processing and cookware sector, and in medical devices within the healthcare, pharmaceuticals and veterinary products sector. Additionally, the compound is found in lubricants used in both industrial manufacturing and chemical processing as well as in the energy, oil and gas sector, along with one further sector. Recorded routes of exposure for this substance include inhalation, oral ingestion, and touch.

Contaminant Type

PFAS

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

Not Available

Average Molecular Mass

Not Available

Monoisotopic Mass

Not Available

CAS Registry Number

63-01-4

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

Not Available

InChI Identifier

InChI=1S/C19H28O3/c1-18-7-5-12(20)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(21)17(19)22/h9,13-17,21-22H,3-8,10H2,1-2H3/t13-,14+,15+,16-,17+,18+,19+/m1/s1

InChI Key

YMCWOAZGWMZGQT-FPNLOETNSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
2061.0 Log mg/kg [1200:3700]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Description	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000007	Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.	Agriculture & land management	Not Available
CEDs000120	Wires and cables?Wires and cables are integral components in the transmission of electrical power and signals.	Electrical & Electronic Equipment	Not Available
CEDs000121	Printed circuit boards?Printed circuit boards (PCBs) are essential components in the manufacturing of electronic devices, serving as the backbone for electrical connections and circuit pathways.	Electrical & Electronic Equipment	Not Available
CEDs000125	Batteries?Batteries are devices that store and release electrical energy through electrochemical reactions.	Electrical & Electronic Equipment	Not Available
CEDs000130	Semiconductors?Semiconductors are materials that possess electrical conductivity between that of conductors and insulators, making them essential for various electronic applications, including transistors, diodes, and integrated circuits.	Electrical & Electronic Equipment	Not Available
CEDs000138	Lubricants?Lubricants are synthetic or petroleum-derived substances used to reduce friction between surfaces in machinery and equipment, enhancing operational efficiency and longevity.	Energy, oil & gas	Not Available
CEDs000147	Food packaging?Food packaging often utilizes synthetic chemicals, such as plastics and coatings, to enhance durability, moisture resistance, and shelf life.	Food, food processing & cookware	Not Available
CEDs000174	Lubricants?Lubricants are synthetic or petroleum-based substances used to reduce friction and wear between moving parts in machinery and equipment.	Industrial manufacturing & chemical processing	Not Available
CEDs000234	Medical devices?Medical devices often incorporate synthetic chemicals in their manufacturing processes, which can contribute to contamination in healthcare settings.	Healthcare, pharmaceuticals & veterinary products	Not Available
CEDs000451	Carpets and Rugs?Carpets and rugs are commonly manufactured using synthetic fibers such as nylon, polyester, and polypropylene, which can be derived from petrochemical sources.	Textiles, leather & furnishings	Not Available
CEDs000454	Synthetic textiles?Synthetic textiles are materials derived from man-made fibers, such as polyester, nylon, and acrylic, which are produced through chemical processes involving petrochemicals.	Textiles, leather & furnishings	Not Available
CEDs000490		Personal care & cosmetics	Not Available
CEDs000492	Cell phones?Cell phones contain a variety of synthetic chemicals and materials, including plastics, metals, and glass, which can contribute to environmental contamination.	Electrical & Electronic Equipment	Not Available
CEDs000493	Capacitors?Capacitors are electronic components that store and release electrical energy, often using dielectric materials that can include synthetic chemicals.	Electrical & Electronic Equipment	Not Available

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Androgen receptor	P15207	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.669 Applicability Domain 0.717 Statistical Significance 6.00e-05 Supporting Reference Compounds 73 E-value 0.467095
Click to view 3D structure	Sex hormone-binding globulin	P04278	Humans	Predicted (SEA)	Prediction Confidence Score 0.646 Applicability Domain 0.717 Statistical Significance 3.00e-05 Supporting Reference Compounds 33 E-value 0.233548
Click to view 3D structure	Corticosteroid-binding globulin	P08185	Humans	Predicted (SEA)	Prediction Confidence Score 0.637 Applicability Domain 0.717 Statistical Significance 3.00e-05 Supporting Reference Compounds 21 E-value 0.233548
Click to view 3D structure	Glucocorticoid receptor	P04150	Humans	Predicted (SEA)	Prediction Confidence Score 0.626 Applicability Domain 0.717 Statistical Significance 1.70e-04 Supporting Reference Compounds 154 E-value 1.32344
Click to view 3D structure	Progesterone receptor	Q690N0	Bos taurus	Predicted (SEA)	Prediction Confidence Score 0.625 Applicability Domain 0.717 Statistical Significance 3.00e-05 Supporting Reference Compounds 40 E-value 0.233548
Click to view 3D structure	Androgen receptor	P10275	Humans	Predicted (SEA)	Prediction Confidence Score 0.613 Applicability Domain 0.717 Statistical Significance 1.90e-04 Supporting Reference Compounds 146 E-value 1.47914
Click to view 3D structure	Mineralocorticoid receptor	P08235	Humans	Predicted (SEA)	Prediction Confidence Score 0.554 Applicability Domain 0.64 Statistical Significance 1.30e-04 Supporting Reference Compounds 74 E-value 1.01204
Click to view 3D structure	Androgen receptor	P19091	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.526 Applicability Domain 0.717 Statistical Significance 2.00e-05 Supporting Reference Compounds 19 E-value 0.155698
Click to view 3D structure	Steroid 17-alpha-hydroxylase/17,20 lyase	P05093	Humans	Predicted (SEA)	Prediction Confidence Score 0.517 Applicability Domain 0.615 Statistical Significance 2.40e-04 Supporting Reference Compounds 69 E-value 1.86838
Click to view 3D structure	Progesterone receptor	P06401	Humans	Predicted (SEA)	Prediction Confidence Score 0.504 Applicability Domain 0.64 Statistical Significance 5.00e-04 Supporting Reference Compounds 119 E-value 3.89246
Click to view 3D structure	Estrogen receptor	P03372	Humans	Predicted (SEA)	Prediction Confidence Score 0.498 Applicability Domain 0.717 Statistical Significance 6.80e-04 Supporting Reference Compounds 201 E-value 5.29375
Click to view 3D structure	Solute carrier organic anion transporter family member 1A1	P46720	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.484 Applicability Domain 0.717 Statistical Significance 6.00e-05 Supporting Reference Compounds 10 E-value 0.467095
Click to view 3D structure	3-oxo-5-alpha-steroid 4-dehydrogenase 1	P18405	Humans	Predicted (SEA)	Prediction Confidence Score 0.476 Applicability Domain 0.615 Statistical Significance 1.00e-04 Supporting Reference Compounds 14 E-value 0.778492
Click to view 3D structure	Aromatase	P11511	Humans	Predicted (SEA)	Prediction Confidence Score 0.475 Applicability Domain 0.717 Statistical Significance 5.20e-04 Supporting Reference Compounds 127 E-value 4.04816
Click to view 3D structure	3-oxo-5-alpha-steroid 4-dehydrogenase 2	P31213	Humans	Predicted (SEA)	Prediction Confidence Score 0.472 Applicability Domain 0.615 Statistical Significance 1.90e-04 Supporting Reference Compounds 19 E-value 1.47914
Click to view 3D structure	Solute carrier family 22 member 3	O88446	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.454 Applicability Domain 0.604 Statistical Significance 4.00e-05 Supporting Reference Compounds 3 E-value 0.311397
Click to view 3D structure	G-protein coupled bile acid receptor 1	Q8TDU6	Humans	Predicted (SEA)	Prediction Confidence Score 0.443 Applicability Domain 0.64 Statistical Significance 0.0015 Supporting Reference Compounds 54 E-value 11.9888
Click to view 3D structure	Sigma non-opioid intracellular receptor 1	Q99720	Humans	Predicted (SEA)	Prediction Confidence Score 0.435 Applicability Domain 0.717 Statistical Significance 0.0067 Supporting Reference Compounds 562 E-value 51.8476
Click to view 3D structure	Estrogen receptor beta	Q92731	Humans	Predicted (SEA)	Prediction Confidence Score 0.434 Applicability Domain 0.717 Statistical Significance 9.80e-04 Supporting Reference Compounds 174 E-value 7.62922
Click to view 3D structure	Nuclear receptor subfamily 1 group I member 3	O35627	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.432 Applicability Domain 0.58 Statistical Significance 1.00e-05 Supporting Reference Compounds 2 E-value 0.0778492
Click to view 3D structure	C-8 sterol isomerase ERG2	P32352	Baker's yeast	Predicted (SEA)	Prediction Confidence Score 0.409 Applicability Domain 0.717 Statistical Significance 3.00e-05 Supporting Reference Compounds 20 E-value 0.233548
Click to view 3D structure	Glucose-6-phosphate 1-dehydrogenase	Q9GRG7	Trypanosoma brucei	Predicted (SEA)	Prediction Confidence Score 0.388 Applicability Domain 0.4 Statistical Significance 3.40e-04 Supporting Reference Compounds 2 E-value 2.64687
Click to view 3D structure	Solute carrier family 22 member 2	Q9R0W2	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.385 Applicability Domain 0.64 Statistical Significance 2.00e-05 Supporting Reference Compounds 14 E-value 0.155698
Click to view 3D structure	Cytochrome P450 3A4	P08684	Humans	Predicted (SEA)	Prediction Confidence Score 0.376 Applicability Domain 0.717 Statistical Significance 0.0327 Supporting Reference Compounds 1538 E-value 254.411
Click to view 3D structure	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase	P9WQP7	Mycobacterium tuberculosis	Predicted (SEA)	Prediction Confidence Score 0.373 Applicability Domain 0.373 Statistical Significance 2.60e-04 Supporting Reference Compounds 1 E-value 2.02408