N-Desmethylmianserin (CED0026825)

Record Information

Version

1.0

Creation Date

2026-04-06 09:06:43 UTC

Update Date

2026-05-21 09:13:14 UTC

SynCED ID

CED0026825

Secondary Accession Numbers

CHEM121135

Identification

Common Name

N-Desmethylmianserin

Class

Small Molecule

Description

N-Desmethylmianserin belongs to the dibenzazepines, a subclass of benzazepines within the organic compounds. This organoheterocyclic compound is found in or released from thirteen recorded sources across multiple sectors. Within the energy, oil and gas sector, as well as industrial manufacturing and chemical processing, it is identified in lubricants. In the healthcare, pharmaceuticals and veterinary products sector, it is associated with medical devices. The compound is also present in food packaging within the food, food processing and cookware sector. It is found in textiles, leather and furnishings, specifically in carpets, rugs, and synthetic textiles. Additionally, it is released from electrical and electronic equipment, including batteries, capacitors, cell phones, printed circuit boards, wires, cables, and one other source. Other recorded sources include one additional sector. Exposure routes for N-Desmethylmianserin include oral, inhalation, and touch.

Contaminant Type

PFAS

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

Not Available

Average Molecular Mass

Not Available

Monoisotopic Mass

Not Available

CAS Registry Number

136315-26-9

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

Not Available

InChI Identifier

InChI=1S/C17H18N2/c1-3-7-15-13(5-1)11-14-6-2-4-8-16(14)19-10-9-18-12-17(15)19/h1-8,17-18H,9-12H2/t17-/m0/s1

InChI Key

ZBILSSSEXRZGKS-KRWDZBQOSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
228.0 Log mg/kg [130:400]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000007	Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.	Agriculture & land management	Not Available
CEDs000120	Wires and cables?Wires and cables are integral components in the transmission of electrical power and signals.	Electrical & Electronic Equipment	Not Available
CEDs000121	Printed circuit boards?Printed circuit boards (PCBs) are essential components in the manufacturing of electronic devices, serving as the backbone for electrical connections and circuit pathways.	Electrical & Electronic Equipment	Not Available
CEDs000125	Batteries?Batteries are devices that store and release electrical energy through electrochemical reactions.	Electrical & Electronic Equipment	Not Available
CEDs000130	Semiconductors?Semiconductors are materials that possess electrical conductivity between that of conductors and insulators, making them essential for various electronic applications, including transistors, diodes, and integrated circuits.	Electrical & Electronic Equipment	Not Available
CEDs000138	Lubricants?Lubricants are synthetic or petroleum-derived substances used to reduce friction between surfaces in machinery and equipment, enhancing operational efficiency and longevity.	Energy, oil & gas	Not Available
CEDs000147	Food packaging?Food packaging often utilizes synthetic chemicals, such as plastics and coatings, to enhance durability, moisture resistance, and shelf life.	Food, food processing & cookware	Not Available
CEDs000174	Lubricants?Lubricants are synthetic or petroleum-based substances used to reduce friction and wear between moving parts in machinery and equipment.	Industrial manufacturing & chemical processing	Not Available
CEDs000234	Medical devices?Medical devices often incorporate synthetic chemicals in their manufacturing processes, which can contribute to contamination in healthcare settings.	Healthcare, pharmaceuticals & veterinary products	Not Available
CEDs000451	Carpets and Rugs?Carpets and rugs are commonly manufactured using synthetic fibers such as nylon, polyester, and polypropylene, which can be derived from petrochemical sources.	Textiles, leather & furnishings	Not Available
CEDs000454	Synthetic textiles?Synthetic textiles are materials derived from man-made fibers, such as polyester, nylon, and acrylic, which are produced through chemical processes involving petrochemicals.	Textiles, leather & furnishings	Not Available
CEDs000490		Personal care & cosmetics	Not Available
CEDs000492	Cell phones?Cell phones contain a variety of synthetic chemicals and materials, including plastics, metals, and glass, which can contribute to environmental contamination.	Electrical & Electronic Equipment	Not Available
CEDs000493	Capacitors?Capacitors are electronic components that store and release electrical energy, often using dielectric materials that can include synthetic chemicals.	Electrical & Electronic Equipment	Not Available

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	5-hydroxytryptamine receptor 2C	P28335	Humans	Predicted (SEA)	Prediction Confidence Score 0.431 Applicability Domain 0.571 Statistical Significance 0.0084 Supporting Reference Compounds 823 E-value 65.4712
Click to view 3D structure	5-hydroxytryptamine receptor 2A	P28223	Humans	Predicted (SEA)	Prediction Confidence Score 0.431 Applicability Domain 0.571 Statistical Significance 0.0125 Supporting Reference Compounds 955 E-value 97.1558
Click to view 3D structure	Histamine H1 receptor	P35367	Humans	Predicted (SEA)	Prediction Confidence Score 0.42 Applicability Domain 0.571 Statistical Significance 0.0066 Supporting Reference Compounds 507 E-value 51.3805
Click to view 3D structure	D(3) dopamine receptor	P35462	Humans	Predicted (SEA)	Prediction Confidence Score 0.412 Applicability Domain 0.571 Statistical Significance 0.0138 Supporting Reference Compounds 861 E-value 107.121
Click to view 3D structure	5-hydroxytryptamine receptor 1A	P08908	Humans	Predicted (SEA)	Prediction Confidence Score 0.412 Applicability Domain 0.571 Statistical Significance 0.0152 Supporting Reference Compounds 953 E-value 118.409
Click to view 3D structure	D(2) dopamine receptor	P14416	Humans	Predicted (SEA)	Prediction Confidence Score 0.41 Applicability Domain 0.571 Statistical Significance 0.0191 Supporting Reference Compounds 1103 E-value 148.458
Click to view 3D structure	Alpha-2A adrenergic receptor	P08913	Humans	Predicted (SEA)	Prediction Confidence Score 0.41 Applicability Domain 0.571 Statistical Significance 0.0047 Supporting Reference Compounds 487 E-value 36.4334
Click to view 3D structure	Alpha-1A adrenergic receptor	P35348	Humans	Predicted (SEA)	Prediction Confidence Score 0.41 Applicability Domain 0.571 Statistical Significance 0.0066 Supporting Reference Compounds 376 E-value 51.0691
Click to view 3D structure	Alpha-2C adrenergic receptor	P18825	Humans	Predicted (SEA)	Prediction Confidence Score 0.41 Applicability Domain 0.571 Statistical Significance 0.0038 Supporting Reference Compounds 386 E-value 29.972
Click to view 3D structure	5-hydroxytryptamine receptor 1D	P28221	Humans	Predicted (SEA)	Prediction Confidence Score 0.408 Applicability Domain 0.571 Statistical Significance 0.004 Supporting Reference Compounds 365 E-value 31.1397
Click to view 3D structure	D(4) dopamine receptor	P21917	Humans	Predicted (SEA)	Prediction Confidence Score 0.407 Applicability Domain 0.571 Statistical Significance 0.0102 Supporting Reference Compounds 524 E-value 79.0948
Click to view 3D structure	D(2) dopamine receptor	P61169	Rat	Predicted (SEA)	Prediction Confidence Score 0.404 Applicability Domain 0.571 Statistical Significance 0.0137 Supporting Reference Compounds 528 E-value 107.043
Click to view 3D structure	5-hydroxytryptamine receptor 2A	P14842	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.396 Applicability Domain 0.571 Statistical Significance 0.0089 Supporting Reference Compounds 380 E-value 69.5972
Click to view 3D structure	5-hydroxytryptamine receptor 2C	P08909	Rat	Predicted (SEA)	Prediction Confidence Score 0.393 Applicability Domain 0.571 Statistical Significance 0.0051 Supporting Reference Compounds 185 E-value 39.7031
Click to view 3D structure	5-hydroxytryptamine receptor 7	P34969	Humans	Predicted (SEA)	Prediction Confidence Score 0.39 Applicability Domain 0.571 Statistical Significance 0.0122 Supporting Reference Compounds 565 E-value 95.2096
Click to view 3D structure	Sodium-dependent serotonin transporter	P31652	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.385 Applicability Domain 0.571 Statistical Significance 0.0076 Supporting Reference Compounds 297 E-value 59.3211
Click to view 3D structure	Norepinephrine transporter	Q9WTR4	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.385 Applicability Domain 0.571 Statistical Significance 0.0027 Supporting Reference Compounds 112 E-value 21.0971
Click to view 3D structure	5-hydroxytryptamine receptor 1A	P19327	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.381 Applicability Domain 0.571 Statistical Significance 0.0154 Supporting Reference Compounds 541 E-value 120.121
Click to view 3D structure	D(1A) dopamine receptor	P18901	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.381 Applicability Domain 0.571 Statistical Significance 0.0066 Supporting Reference Compounds 206 E-value 51.0691
Click to view 3D structure	5-hydroxytryptamine receptor 1B	P28564	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.371 Applicability Domain 0.571 Statistical Significance 0.0047 Supporting Reference Compounds 154 E-value 36.9784
Click to view 3D structure	5-hydroxytryptamine receptor 6	P50406	Humans	Predicted (SEA)	Prediction Confidence Score 0.371 Applicability Domain 0.571 Statistical Significance 0.013 Supporting Reference Compounds 536 E-value 101.36
Click to view 3D structure	5-hydroxytryptamine receptor 2B	P41595	Humans	Predicted (SEA)	Prediction Confidence Score 0.36 Applicability Domain 0.571 Statistical Significance 0.016 Supporting Reference Compounds 686 E-value 124.948
Click to view 3D structure	Sodium-dependent dopamine transporter	P23977	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.347 Applicability Domain 0.571 Statistical Significance 0.008 Supporting Reference Compounds 203 E-value 61.968
Click to view 3D structure	Sodium-dependent serotonin transporter	P31645	Humans	Predicted (SEA)	Prediction Confidence Score 0.34 Applicability Domain 0.571 Statistical Significance 0.0238 Supporting Reference Compounds 593 E-value 185.281
Click to view 3D structure	Sodium-dependent noradrenaline transporter	P23975	Humans	Predicted (SEA)	Prediction Confidence Score 0.337 Applicability Domain 0.571 Statistical Significance 0.0157 Supporting Reference Compounds 451 E-value 122.145