(S)-(-)-carvedilol (CED0002395)

Record Information

Version

1.0

Creation Date

2026-04-06 09:08:52 UTC

Update Date

2026-05-21 09:17:53 UTC

SynCED ID

CED0002395

Secondary Accession Numbers

CHEM121200

Identification

Common Name

(S)-(-)-carvedilol

Class

Small Molecule

Description

(S)-(-)-carvedilol belongs to the carbazoles, a subclass of indoles and derivatives within the organic compounds. This organoheterocyclic compound is found in or released from 13 recorded sources across several sectors. Within the healthcare, pharmaceuticals & veterinary products sector, it is associated with medical devices. In the energy, oil & gas and industrial manufacturing & chemical processing sectors, it is identified in lubricants. The compound is also linked to the textiles, leather & furnishings sector, specifically in carpets, rugs, and synthetic textiles. It is found in food packaging within the food, food processing & cookware sector. Additionally, it is released from electrical & electronic equipment, including batteries, capacitors, printed circuit boards, cell phones, wires, cables, and one other source. Recorded exposure routes for (S)-(-)-carvedilol include oral, inhalation, and touch.

Contaminant Type

PFAS

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

Not Available

Average Molecular Mass

Not Available

Monoisotopic Mass

Not Available

CAS Registry Number

95094-00-1

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

Not Available

InChI Identifier

InChI=1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3/t17-/m0/s1

InChI Key

OGHNVEJMJSYVRP-KRWDZBQOSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Toxicity Values

Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Description	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000007	Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.	Agriculture & land management	Not Available
CEDs000120	Wires and cables?Wires and cables are integral components in the transmission of electrical power and signals.	Electrical & Electronic Equipment	Not Available
CEDs000121	Printed circuit boards?Printed circuit boards (PCBs) are essential components in the manufacturing of electronic devices, serving as the backbone for electrical connections and circuit pathways.	Electrical & Electronic Equipment	Not Available
CEDs000125	Batteries?Batteries are devices that store and release electrical energy through electrochemical reactions.	Electrical & Electronic Equipment	Not Available
CEDs000130	Semiconductors?Semiconductors are materials that possess electrical conductivity between that of conductors and insulators, making them essential for various electronic applications, including transistors, diodes, and integrated circuits.	Electrical & Electronic Equipment	Not Available
CEDs000138	Lubricants?Lubricants are synthetic or petroleum-derived substances used to reduce friction between surfaces in machinery and equipment, enhancing operational efficiency and longevity.	Energy, oil & gas	Not Available
CEDs000147	Food packaging?Food packaging often utilizes synthetic chemicals, such as plastics and coatings, to enhance durability, moisture resistance, and shelf life.	Food, food processing & cookware	Not Available
CEDs000174	Lubricants?Lubricants are synthetic or petroleum-based substances used to reduce friction and wear between moving parts in machinery and equipment.	Industrial manufacturing & chemical processing	Not Available
CEDs000234	Medical devices?Medical devices often incorporate synthetic chemicals in their manufacturing processes, which can contribute to contamination in healthcare settings.	Healthcare, pharmaceuticals & veterinary products	Not Available
CEDs000451	Carpets and Rugs?Carpets and rugs are commonly manufactured using synthetic fibers such as nylon, polyester, and polypropylene, which can be derived from petrochemical sources.	Textiles, leather & furnishings	Not Available
CEDs000454	Synthetic textiles?Synthetic textiles are materials derived from man-made fibers, such as polyester, nylon, and acrylic, which are produced through chemical processes involving petrochemicals.	Textiles, leather & furnishings	Not Available
CEDs000490		Personal care & cosmetics	Not Available
CEDs000492	Cell phones?Cell phones contain a variety of synthetic chemicals and materials, including plastics, metals, and glass, which can contribute to environmental contamination.	Electrical & Electronic Equipment	Not Available
CEDs000493	Capacitors?Capacitors are electronic components that store and release electrical energy, often using dielectric materials that can include synthetic chemicals.	Electrical & Electronic Equipment	Not Available
CEDs000696	Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.	Industrial manufacturing & chemical processing	PubChem
CEDs000744	Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.	Wastewater, sanitation & biosolids	PubChem

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Beta-2 adrenergic receptor	P07550	Humans	Predicted (SEA)	Prediction Confidence Score 0.793 Applicability Domain 1.0 Statistical Significance 2.00e-05 Supporting Reference Compounds 258 E-value 0.155698
Click to view 3D structure	D(2) dopamine receptor	P14416	Humans	Predicted (SEA)	Prediction Confidence Score 0.751 Applicability Domain 1.0 Statistical Significance 2.90e-04 Supporting Reference Compounds 1103 E-value 2.25763
Click to view 3D structure	Beta-1 adrenergic receptor	P34971	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.666 Applicability Domain 1.0 Statistical Significance 1.00e-05 Supporting Reference Compounds 13 E-value 0.0778492
Click to view 3D structure	Beta-1 adrenergic receptor	P08588	Humans	Predicted (SEA)	Prediction Confidence Score 0.556 Applicability Domain 1.0 Statistical Significance 3.70e-04 Supporting Reference Compounds 180 E-value 2.88042
Click to view 3D structure	5-hydroxytryptamine receptor 1A	P19327	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.525 Applicability Domain 1.0 Statistical Significance 0.0034 Supporting Reference Compounds 541 E-value 26.7801
Click to view 3D structure	5-hydroxytryptamine receptor 1B	P28564	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.525 Applicability Domain 1.0 Statistical Significance 3.70e-04 Supporting Reference Compounds 154 E-value 2.88042
Click to view 3D structure	Beta-3 adrenergic receptor	P13945	Humans	Predicted (SEA)	Prediction Confidence Score 0.524 Applicability Domain 1.0 Statistical Significance 3.50e-04 Supporting Reference Compounds 145 E-value 2.72472
Click to view 3D structure	Sodium-dependent serotonin transporter	P31645	Humans	Predicted (SEA)	Prediction Confidence Score 0.521 Applicability Domain 1.0 Statistical Significance 0.002 Supporting Reference Compounds 593 E-value 15.4141
Click to view 3D structure	5-hydroxytryptamine receptor 2B	P41595	Humans	Predicted (SEA)	Prediction Confidence Score 0.518 Applicability Domain 1.0 Statistical Significance 0.0018 Supporting Reference Compounds 686 E-value 13.7793
Click to view 3D structure	5-hydroxytryptamine receptor 2C	P28335	Humans	Predicted (SEA)	Prediction Confidence Score 0.516 Applicability Domain 1.0 Statistical Significance 0.0027 Supporting Reference Compounds 823 E-value 21.2528
Click to view 3D structure	5-hydroxytryptamine receptor 2A	P28223	Humans	Predicted (SEA)	Prediction Confidence Score 0.516 Applicability Domain 1.0 Statistical Significance 0.0039 Supporting Reference Compounds 955 E-value 30.439
Click to view 3D structure	5-hydroxytryptamine receptor 6	P50406	Humans	Predicted (SEA)	Prediction Confidence Score 0.516 Applicability Domain 1.0 Statistical Significance 0.0015 Supporting Reference Compounds 536 E-value 11.7552
Click to view 3D structure	Voltage-gated inwardly rectifying potassium channel KCNH2	Q12809	Humans	Predicted (SEA)	Prediction Confidence Score 0.498 Applicability Domain 1.0 Statistical Significance 0.0063 Supporting Reference Compounds 1498 E-value 49.4343
Click to view 3D structure	Beta-1 adrenergic receptor	P18090	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.497 Applicability Domain 1.0 Statistical Significance 1.60e-04 Supporting Reference Compounds 43 E-value 1.24559
Click to view 3D structure	D(3) dopamine receptor	P35462	Humans	Predicted (SEA)	Prediction Confidence Score 0.483 Applicability Domain 1.0 Statistical Significance 0.0061 Supporting Reference Compounds 861 E-value 47.7216
Click to view 3D structure	Sodium-dependent dopamine transporter	Q01959	Humans	Predicted (SEA)	Prediction Confidence Score 0.476 Applicability Domain 1.0 Statistical Significance 0.002 Supporting Reference Compounds 506 E-value 15.2584
Click to view 3D structure	Sodium-dependent noradrenaline transporter	P23975	Humans	Predicted (SEA)	Prediction Confidence Score 0.476 Applicability Domain 1.0 Statistical Significance 0.0015 Supporting Reference Compounds 451 E-value 11.366
Click to view 3D structure	Alpha-1D adrenergic receptor	P25100	Humans	Predicted (SEA)	Prediction Confidence Score 0.472 Applicability Domain 1.0 Statistical Significance 0.0015 Supporting Reference Compounds 258 E-value 11.5995
Click to view 3D structure	Alpha-1A adrenergic receptor	P43140	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.468 Applicability Domain 1.0 Statistical Significance 0.0018 Supporting Reference Compounds 208 E-value 14.0129
Click to view 3D structure	Alpha-1B adrenergic receptor	P15823	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.468 Applicability Domain 1.0 Statistical Significance 4.60e-04 Supporting Reference Compounds 130 E-value 3.58106
Click to view 3D structure	D(1A) dopamine receptor	P21728	Humans	Predicted (SEA)	Prediction Confidence Score 0.461 Applicability Domain 1.0 Statistical Significance 0.004 Supporting Reference Compounds 425 E-value 30.9061
Click to view 3D structure	Alpha-2A adrenergic receptor	P08913	Humans	Predicted (SEA)	Prediction Confidence Score 0.456 Applicability Domain 1.0 Statistical Significance 0.0024 Supporting Reference Compounds 487 E-value 19.0731
Click to view 3D structure	Alpha-2C adrenergic receptor	P18825	Humans	Predicted (SEA)	Prediction Confidence Score 0.456 Applicability Domain 1.0 Statistical Significance 0.0019 Supporting Reference Compounds 386 E-value 15.1806
Click to view 3D structure	Alpha-2B adrenergic receptor	P18089	Humans	Predicted (SEA)	Prediction Confidence Score 0.422 Applicability Domain 1.0 Statistical Significance 0.0028 Supporting Reference Compounds 340 E-value 21.8756
Click to view 3D structure	ATP-dependent translocase ABCB1	P08183	Humans	Predicted (SEA)	Prediction Confidence Score 0.417 Applicability Domain 1.0 Statistical Significance 0.0014 Supporting Reference Compounds 139 E-value 10.821