3-Hydroxy-6-methoxyflavone (CED0025286)

Record Information

Version

1.0

Creation Date

2026-04-06 09:12:00 UTC

Update Date

2026-05-21 09:33:28 UTC

SynCED ID

CED0025286

Secondary Accession Numbers

CHEM121277

Identification

Common Name

3-Hydroxy-6-methoxyflavone

Class

Small Molecule

Description

3-Hydroxy-6-methoxyflavone belongs to the flavones, a subclass of flavonoids within the organic compounds. This substance is categorized within the superclass of phenylpropanoids and polyketides. The compound is found in or released from 13 recorded sources across multiple sectors. Within the electrical and electronic equipment sector, it is associated with capacitors, cell phones, batteries, printed circuit boards, wires and cables, and one additional source. In the sector of textiles, leather and furnishings, it is found in carpets, rugs, and synthetic textiles. It is also present in food packaging within the food, food processing and cookware sector, and in medical devices within the healthcare, pharmaceuticals and veterinary products sector. Furthermore, the compound is identified in lubricants used in both energy, oil and gas as well as industrial manufacturing and chemical processing, along with one other sector. Recorded exposure routes for this compound include touch, oral, and inhalation.

Contaminant Type

PFAS

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

Not Available

Average Molecular Mass

Not Available

Monoisotopic Mass

Not Available

CAS Registry Number

93176-00-2

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

Not Available

InChI Identifier

InChI=1S/C16H12O4/c1-19-11-7-8-13-12(9-11)14(17)15(18)16(20-13)10-5-3-2-4-6-10/h2-9,18H,1H3

InChI Key

OGURJSOPVFCIOO-UHFFFAOYSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
3707.0 Log mg/kg [2100:6600]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Description	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000007	Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.	Agriculture & land management	Not Available
CEDs000120	Wires and cables?Wires and cables are integral components in the transmission of electrical power and signals.	Electrical & Electronic Equipment	Not Available
CEDs000121	Printed circuit boards?Printed circuit boards (PCBs) are essential components in the manufacturing of electronic devices, serving as the backbone for electrical connections and circuit pathways.	Electrical & Electronic Equipment	Not Available
CEDs000125	Batteries?Batteries are devices that store and release electrical energy through electrochemical reactions.	Electrical & Electronic Equipment	Not Available
CEDs000130	Semiconductors?Semiconductors are materials that possess electrical conductivity between that of conductors and insulators, making them essential for various electronic applications, including transistors, diodes, and integrated circuits.	Electrical & Electronic Equipment	Not Available
CEDs000138	Lubricants?Lubricants are synthetic or petroleum-derived substances used to reduce friction between surfaces in machinery and equipment, enhancing operational efficiency and longevity.	Energy, oil & gas	Not Available
CEDs000147	Food packaging?Food packaging often utilizes synthetic chemicals, such as plastics and coatings, to enhance durability, moisture resistance, and shelf life.	Food, food processing & cookware	Not Available
CEDs000174	Lubricants?Lubricants are synthetic or petroleum-based substances used to reduce friction and wear between moving parts in machinery and equipment.	Industrial manufacturing & chemical processing	Not Available
CEDs000234	Medical devices?Medical devices often incorporate synthetic chemicals in their manufacturing processes, which can contribute to contamination in healthcare settings.	Healthcare, pharmaceuticals & veterinary products	Not Available
CEDs000451	Carpets and Rugs?Carpets and rugs are commonly manufactured using synthetic fibers such as nylon, polyester, and polypropylene, which can be derived from petrochemical sources.	Textiles, leather & furnishings	Not Available
CEDs000454	Synthetic textiles?Synthetic textiles are materials derived from man-made fibers, such as polyester, nylon, and acrylic, which are produced through chemical processes involving petrochemicals.	Textiles, leather & furnishings	Not Available
CEDs000490		Personal care & cosmetics	Not Available
CEDs000492	Cell phones?Cell phones contain a variety of synthetic chemicals and materials, including plastics, metals, and glass, which can contribute to environmental contamination.	Electrical & Electronic Equipment	Not Available
CEDs000493	Capacitors?Capacitors are electronic components that store and release electrical energy, often using dielectric materials that can include synthetic chemicals.	Electrical & Electronic Equipment	Not Available

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Cytochrome P450 1B1	Q16678	Humans	Predicted (SEA)	Prediction Confidence Score 0.485 Applicability Domain 0.625 Statistical Significance 6.70e-04 Supporting Reference Compounds 88 E-value 5.2159
Click to view 3D structure	ATP-dependent translocase ABCB1	P08183	Humans	Predicted (SEA)	Prediction Confidence Score 0.477 Applicability Domain 0.625 Statistical Significance 6.30e-04 Supporting Reference Compounds 139 E-value 4.9045
Click to view 3D structure	Carbonic anhydrase 12	O43570	Humans	Predicted (SEA)	Prediction Confidence Score 0.464 Applicability Domain 0.625 Statistical Significance 0.0019 Supporting Reference Compounds 332 E-value 14.6357
Click to view 3D structure	Carbonic anhydrase 1	P00915	Humans	Predicted (SEA)	Prediction Confidence Score 0.464 Applicability Domain 0.625 Statistical Significance 0.0025 Supporting Reference Compounds 407 E-value 19.2288
Click to view 3D structure	Carbonic anhydrase 2	P00918	Humans	Predicted (SEA)	Prediction Confidence Score 0.46 Applicability Domain 0.625 Statistical Significance 0.003 Supporting Reference Compounds 472 E-value 23.1991
Click to view 3D structure	Poly [ADP-ribose] polymerase tankyrase-1	O95271	Humans	Predicted (SEA)	Prediction Confidence Score 0.446 Applicability Domain 0.523 Statistical Significance 9.60e-04 Supporting Reference Compounds 94 E-value 7.47353
Click to view 3D structure	Carbonic anhydrase 9	Q16790	Humans	Predicted (SEA)	Prediction Confidence Score 0.44 Applicability Domain 0.625 Statistical Significance 0.0033 Supporting Reference Compounds 372 E-value 25.8459
Click to view 3D structure	Cytochrome P450 1A2	P05177	Humans	Predicted (SEA)	Prediction Confidence Score 0.429 Applicability Domain 0.531 Statistical Significance 0.006 Supporting Reference Compounds 793 E-value 46.7874
Click to view 3D structure	Cytochrome P450 1A1	P04798	Humans	Predicted (SEA)	Prediction Confidence Score 0.429 Applicability Domain 0.531 Statistical Significance 1.00e-03 Supporting Reference Compounds 77 E-value 7.78492
Click to view 3D structure	Pyruvate kinase PKM	P14618	Humans	Predicted (SEA)	Prediction Confidence Score 0.417 Applicability Domain 0.625 Statistical Significance 2.10e-04 Supporting Reference Compounds 29 E-value 1.63483
Click to view 3D structure	Carbonic anhydrase 7	P43166	Humans	Predicted (SEA)	Prediction Confidence Score 0.409 Applicability Domain 0.489 Statistical Significance 0.0031 Supporting Reference Compounds 242 E-value 23.8219
Click to view 3D structure	Carbonic anhydrase 4	P22748	Humans	Predicted (SEA)	Prediction Confidence Score 0.409 Applicability Domain 0.489 Statistical Significance 0.0022 Supporting Reference Compounds 193 E-value 17.2825
Click to view 3D structure	ATP-dependent translocase ABCB1	P21447	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.408 Applicability Domain 0.531 Statistical Significance 1.20e-04 Supporting Reference Compounds 23 E-value 0.934191
Click to view 3D structure	Amine oxidase [flavin-containing] A	P21397	Humans	Predicted (SEA)	Prediction Confidence Score 0.408 Applicability Domain 0.531 Statistical Significance 0.0028 Supporting Reference Compounds 241 E-value 21.9535
Click to view 3D structure	Xanthine dehydrogenase/oxidase	P47989	Humans	Predicted (SEA)	Prediction Confidence Score 0.4 Applicability Domain 0.489 Statistical Significance 6.40e-04 Supporting Reference Compounds 37 E-value 4.98235
Click to view 3D structure	Long-chain-fatty-acid--CoA ligase 6	Q9UKU0	Humans	Predicted (SEA)	Prediction Confidence Score 0.393 Applicability Domain 0.393 Statistical Significance 1.20e-04 Supporting Reference Compounds 1 E-value 0.934191
Click to view 3D structure	Receptor-type tyrosine-protein kinase FLT3	P36888	Humans	Predicted (SEA)	Prediction Confidence Score 0.392 Applicability Domain 0.489 Statistical Significance 0.0328 Supporting Reference Compounds 1274 E-value 255.423
Click to view 3D structure	Inositol hexakisphosphate kinase 2	Q9UHH9	Humans	Predicted (SEA)	Prediction Confidence Score 0.385 Applicability Domain 0.462 Statistical Significance 6.70e-04 Supporting Reference Compounds 13 E-value 5.2159
Click to view 3D structure	Carbonic anhydrase 14	Q9ULX7	Humans	Predicted (SEA)	Prediction Confidence Score 0.383 Applicability Domain 0.407 Statistical Significance 0.0034 Supporting Reference Compounds 172 E-value 26.5466
Click to view 3D structure	Carbonic anhydrase 5A, mitochondrial	P35218	Humans	Predicted (SEA)	Prediction Confidence Score 0.383 Applicability Domain 0.407 Statistical Significance 0.0032 Supporting Reference Compounds 165 E-value 24.6004
Click to view 3D structure	Adenosine receptor A1	P25099	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.383 Applicability Domain 0.489 Statistical Significance 0.0086 Supporting Reference Compounds 221 E-value 66.7946
Click to view 3D structure	Carbonic anhydrase 15	Q99N23	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.379 Applicability Domain 0.407 Statistical Significance 0.0018 Supporting Reference Compounds 78 E-value 13.935
Click to view 3D structure	Broad substrate specificity ATP-binding cassette transporter ABCG2	Q9UNQ0	Humans	Predicted (SEA)	Prediction Confidence Score 0.378 Applicability Domain 0.523 Statistical Significance 0.0053 Supporting Reference Compounds 126 E-value 41.1044
Click to view 3D structure	Acetylcholinesterase	P22303	Humans	Predicted (SEA)	Prediction Confidence Score 0.376 Applicability Domain 0.489 Statistical Significance 0.0107 Supporting Reference Compounds 406 E-value 83.2987
Click to view 3D structure	Aromatase	P11511	Humans	Predicted (SEA)	Prediction Confidence Score 0.376 Applicability Domain 0.489 Statistical Significance 0.0026 Supporting Reference Compounds 127 E-value 20.3965