7-Hydroxy-2p-methoxyflavone (CED0078273)

Record Information

Version

1.0

Creation Date

2026-04-06 09:15:28 UTC

Update Date

2026-05-21 09:55:04 UTC

SynCED ID

CED0078273

Secondary Accession Numbers

CHEM121347

Identification

Common Name

7-Hydroxy-2p-methoxyflavone

Class

Small Molecule

Description

7-Hydroxy-2p-methoxyflavone belongs to the o-methylated flavonoids, a subclass of flavonoids within the organic compounds. This compound is categorized under the superclass of phenylpropanoids and polyketides. It has been identified in or released from 13 recorded sources across several sectors. Within the electrical and electronic equipment sector, it is associated with cell phones, capacitors, wires and cables, batteries, and printed circuit boards, among one other source. In the textiles, leather and furnishings sector, it is found in synthetic textiles as well as carpets and rugs. It is present in food packaging within the food, food processing and cookware sector, and in medical devices within the healthcare, pharmaceuticals and veterinary products sector. Additionally, the compound is found in lubricants used in both the energy, oil and gas sector and the industrial manufacturing and chemical processing sector, along with one other sector. Recorded exposure routes for this compound include inhalation, oral exposure, and touch.

Contaminant Type

PFAS

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

Not Available

Average Molecular Mass

Not Available

Monoisotopic Mass

Not Available

CAS Registry Number

77298-65-8

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

Not Available

InChI Identifier

InChI=1S/C16H12O4/c1-19-14-5-3-2-4-12(14)16-9-13(18)11-7-6-10(17)8-15(11)20-16/h2-9,17H,1H3

InChI Key

PFEQKIBOPJQNBI-UHFFFAOYSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
3272.0 Log mg/kg [1800:5800]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Description	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000007	Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.	Agriculture & land management	Not Available
CEDs000120	Wires and cables?Wires and cables are integral components in the transmission of electrical power and signals.	Electrical & Electronic Equipment	Not Available
CEDs000121	Printed circuit boards?Printed circuit boards (PCBs) are essential components in the manufacturing of electronic devices, serving as the backbone for electrical connections and circuit pathways.	Electrical & Electronic Equipment	Not Available
CEDs000125	Batteries?Batteries are devices that store and release electrical energy through electrochemical reactions.	Electrical & Electronic Equipment	Not Available
CEDs000130	Semiconductors?Semiconductors are materials that possess electrical conductivity between that of conductors and insulators, making them essential for various electronic applications, including transistors, diodes, and integrated circuits.	Electrical & Electronic Equipment	Not Available
CEDs000138	Lubricants?Lubricants are synthetic or petroleum-derived substances used to reduce friction between surfaces in machinery and equipment, enhancing operational efficiency and longevity.	Energy, oil & gas	Not Available
CEDs000147	Food packaging?Food packaging often utilizes synthetic chemicals, such as plastics and coatings, to enhance durability, moisture resistance, and shelf life.	Food, food processing & cookware	Not Available
CEDs000174	Lubricants?Lubricants are synthetic or petroleum-based substances used to reduce friction and wear between moving parts in machinery and equipment.	Industrial manufacturing & chemical processing	Not Available
CEDs000234	Medical devices?Medical devices often incorporate synthetic chemicals in their manufacturing processes, which can contribute to contamination in healthcare settings.	Healthcare, pharmaceuticals & veterinary products	Not Available
CEDs000451	Carpets and Rugs?Carpets and rugs are commonly manufactured using synthetic fibers such as nylon, polyester, and polypropylene, which can be derived from petrochemical sources.	Textiles, leather & furnishings	Not Available
CEDs000454	Synthetic textiles?Synthetic textiles are materials derived from man-made fibers, such as polyester, nylon, and acrylic, which are produced through chemical processes involving petrochemicals.	Textiles, leather & furnishings	Not Available
CEDs000490		Personal care & cosmetics	Not Available
CEDs000492	Cell phones?Cell phones contain a variety of synthetic chemicals and materials, including plastics, metals, and glass, which can contribute to environmental contamination.	Electrical & Electronic Equipment	Not Available
CEDs000493	Capacitors?Capacitors are electronic components that store and release electrical energy, often using dielectric materials that can include synthetic chemicals.	Electrical & Electronic Equipment	Not Available

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Poly [ADP-ribose] polymerase tankyrase-1	O95271	Humans	Predicted (SEA)	Prediction Confidence Score 0.511 Applicability Domain 0.609 Statistical Significance 4.30e-04 Supporting Reference Compounds 94 E-value 3.34752
Click to view 3D structure	Aromatase	P11511	Humans	Predicted (SEA)	Prediction Confidence Score 0.496 Applicability Domain 0.605 Statistical Significance 3.50e-04 Supporting Reference Compounds 127 E-value 2.72472
Click to view 3D structure	Poly [ADP-ribose] polymerase tankyrase-2	Q9H2K2	Humans	Predicted (SEA)	Prediction Confidence Score 0.46 Applicability Domain 0.609 Statistical Significance 7.70e-04 Supporting Reference Compounds 90 E-value 5.99439
Click to view 3D structure	Cytochrome P450 1B1	Q16678	Humans	Predicted (SEA)	Prediction Confidence Score 0.45 Applicability Domain 0.605 Statistical Significance 0.0011 Supporting Reference Compounds 88 E-value 8.71911
Click to view 3D structure	Cytochrome P450 1A2	P05177	Humans	Predicted (SEA)	Prediction Confidence Score 0.447 Applicability Domain 0.605 Statistical Significance 0.0047 Supporting Reference Compounds 793 E-value 36.9784
Click to view 3D structure	Carbonic anhydrase 9	Q16790	Humans	Predicted (SEA)	Prediction Confidence Score 0.444 Applicability Domain 0.605 Statistical Significance 0.0031 Supporting Reference Compounds 372 E-value 24.3668
Click to view 3D structure	Carbonic anhydrase 12	O43570	Humans	Predicted (SEA)	Prediction Confidence Score 0.444 Applicability Domain 0.605 Statistical Significance 0.0027 Supporting Reference Compounds 332 E-value 20.9414
Click to view 3D structure	Adenosine receptor A2a	P30543	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.431 Applicability Domain 0.605 Statistical Significance 0.0056 Supporting Reference Compounds 174 E-value 43.4399
Click to view 3D structure	Adenosine receptor A1	P25099	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.431 Applicability Domain 0.605 Statistical Significance 0.0058 Supporting Reference Compounds 221 E-value 45.5418
Click to view 3D structure	Carbonic anhydrase 2	P00918	Humans	Predicted (SEA)	Prediction Confidence Score 0.428 Applicability Domain 0.605 Statistical Significance 0.0049 Supporting Reference Compounds 472 E-value 38.5354
Click to view 3D structure	Carbonic anhydrase 1	P00915	Humans	Predicted (SEA)	Prediction Confidence Score 0.428 Applicability Domain 0.605 Statistical Significance 0.0045 Supporting Reference Compounds 407 E-value 35.3435
Click to view 3D structure	Protein deacetylase HDAC6	Q9UBN7	Humans	Predicted (SEA)	Prediction Confidence Score 0.427 Applicability Domain 0.583 Statistical Significance 0.0056 Supporting Reference Compounds 553 E-value 43.7513
Click to view 3D structure	Pyruvate kinase PKM	P14618	Humans	Predicted (SEA)	Prediction Confidence Score 0.42 Applicability Domain 0.605 Statistical Significance 2.00e-04 Supporting Reference Compounds 29 E-value 1.55698
Click to view 3D structure	Cytochrome P450 1A1	P04798	Humans	Predicted (SEA)	Prediction Confidence Score 0.407 Applicability Domain 0.426 Statistical Significance 0.0013 Supporting Reference Compounds 77 E-value 9.9647
Click to view 3D structure	Aldo-keto reductase family 1 member B10	O60218	Humans	Predicted (SEA)	Prediction Confidence Score 0.405 Applicability Domain 0.605 Statistical Significance 8.00e-04 Supporting Reference Compounds 49 E-value 6.22794
Click to view 3D structure	Poly [ADP-ribose] polymerase 1	P09874	Humans	Predicted (SEA)	Prediction Confidence Score 0.401 Applicability Domain 0.511 Statistical Significance 0.0027 Supporting Reference Compounds 146 E-value 21.175
Click to view 3D structure	Large T antigen	P03070	Simian virus 40	Predicted (SEA)	Prediction Confidence Score 0.397 Applicability Domain 0.52 Statistical Significance 3.20e-04 Supporting Reference Compounds 78 E-value 2.49118
Click to view 3D structure	Multidrug resistance-associated protein 1	P33527	Humans	Predicted (SEA)	Prediction Confidence Score 0.391 Applicability Domain 0.426 Statistical Significance 6.00e-04 Supporting Reference Compounds 49 E-value 4.67095
Click to view 3D structure	Androgen receptor	P10275	Humans	Predicted (SEA)	Prediction Confidence Score 0.387 Applicability Domain 0.511 Statistical Significance 0.0029 Supporting Reference Compounds 146 E-value 22.3427
Click to view 3D structure	Receptor-type tyrosine-protein kinase FLT3	P36888	Humans	Predicted (SEA)	Prediction Confidence Score 0.386 Applicability Domain 0.404 Statistical Significance 0.0353 Supporting Reference Compounds 1274 E-value 274.73
Click to view 3D structure	Aldo-keto reductase family 1 member B1	P15121	Humans	Predicted (SEA)	Prediction Confidence Score 0.384 Applicability Domain 0.438 Statistical Significance 0.0018 Supporting Reference Compounds 84 E-value 14.2464
Click to view 3D structure	Aldo-keto reductase family 1 member B1	P07943	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.383 Applicability Domain 0.426 Statistical Significance 0.0013 Supporting Reference Compounds 70 E-value 10.1982
Click to view 3D structure	17-beta-hydroxysteroid dehydrogenase type 1	P14061	Humans	Predicted (SEA)	Prediction Confidence Score 0.377 Applicability Domain 0.605 Statistical Significance 8.80e-04 Supporting Reference Compounds 42 E-value 6.85073
Click to view 3D structure	Beta Lactamase	Q932Y6	Pseudomonas aeruginosa	Predicted (SEA)	Prediction Confidence Score 0.371 Applicability Domain 0.471 Statistical Significance 2.80e-04 Supporting Reference Compounds 91 E-value 2.17978
Click to view 3D structure	Luciferin 4-monooxygenase	P08659	Photinus pyralis	Predicted (SEA)	Prediction Confidence Score 0.37 Applicability Domain 0.583 Statistical Significance 9.80e-04 Supporting Reference Compounds 114 E-value 7.62922