2Beta-Hydroxy-progesterone (CED0187123)

Record Information
Version1.0
Creation Date2026-04-06 09:25:48 UTC
Update Date2026-05-21 10:14:53 UTC
SynCED IDCED0187123
Secondary Accession Numbers
  • CHEM121577
Identification
Common Name2Beta-Hydroxy-progesterone
ClassSmall Molecule
Description
2Beta-Hydroxy-progesterone belongs to the pregnane steroids, a subclass of steroids and steroid derivatives within the organic compounds. This substance is categorized under the superclass of lipids and lipid-like molecules. The compound has been identified in or released from 13 recorded sources across several diverse sectors. Within the healthcare, pharmaceuticals & veterinary products sector, it is associated with medical devices. In the energy, oil & gas and industrial manufacturing & chemical processing sectors, it is found in lubricants. Its presence is also recorded in food packaging within the food, food processing & cookware sector. Additionally, it is found in textiles, leather & furnishings, specifically in synthetic textiles as well as carpets and rugs. The compound is also linked to electrical & electronic equipment, including cell phones, capacitors, wires and cables, batteries, and printed circuit boards, among one other item. It has been recorded in one additional sector. Human exposure to 2Beta-Hydroxy-progesterone may occur through inhalation, oral intake, or touch.
Contaminant Type
  • PFAS
Chemical Structure
MOLSDFPDBSMILESInChI
SynonymsNot Available
Chemical FormulaNot Available
Average Molecular MassNot Available
Monoisotopic MassNot Available
CAS Registry NumberNot Available
IUPAC NameNot Available
Traditional NameNot Available
SMILESNot Available
InChI IdentifierInChI=1S/C21H30O3/c1-12(22)15-6-7-16-14-5-4-13-10-18(23)19(24)11-21(13,3)17(14)8-9-20(15,16)2/h10,14-17,19,24H,4-9,11H2,1-3H3/t14-,15+,16-,17-,19-,20+,21-/m0/s1
InChI KeyBOZZHCVRWNSXMR-QOJGXCKPSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Toxicity Values
Toxicity ValueOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalToxicity RatingReference
2698.0 Log mg/kg [1500:4800]RatLD50oralpredictedNot AvailableNot Available
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
CEDs000007Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.Agriculture & land managementNot Available
CEDs000120Wires and cables?Wires and cables are integral components in the transmission of electrical power and signals.Electrical & Electronic EquipmentNot Available
CEDs000121Printed circuit boards?Printed circuit boards (PCBs) are essential components in the manufacturing of electronic devices, serving as the backbone for electrical connections and circuit pathways.Electrical & Electronic EquipmentNot Available
CEDs000125Batteries?Batteries are devices that store and release electrical energy through electrochemical reactions.Electrical & Electronic EquipmentNot Available
CEDs000130Semiconductors?Semiconductors are materials that possess electrical conductivity between that of conductors and insulators, making them essential for various electronic applications, including transistors, diodes, and integrated circuits.Electrical & Electronic EquipmentNot Available
CEDs000138Lubricants?Lubricants are synthetic or petroleum-derived substances used to reduce friction between surfaces in machinery and equipment, enhancing operational efficiency and longevity.Energy, oil & gasNot Available
CEDs000147Food packaging?Food packaging often utilizes synthetic chemicals, such as plastics and coatings, to enhance durability, moisture resistance, and shelf life.Food, food processing & cookwareNot Available
CEDs000174Lubricants?Lubricants are synthetic or petroleum-based substances used to reduce friction and wear between moving parts in machinery and equipment.Industrial manufacturing & chemical processingNot Available
CEDs000234Medical devices?Medical devices often incorporate synthetic chemicals in their manufacturing processes, which can contribute to contamination in healthcare settings.Healthcare, pharmaceuticals & veterinary productsNot Available
CEDs000451Carpets and Rugs?Carpets and rugs are commonly manufactured using synthetic fibers such as nylon, polyester, and polypropylene, which can be derived from petrochemical sources.Textiles, leather & furnishingsNot Available
CEDs000454Synthetic textiles?Synthetic textiles are materials derived from man-made fibers, such as polyester, nylon, and acrylic, which are produced through chemical processes involving petrochemicals.Textiles, leather & furnishingsNot Available
CEDs000490Personal care & cosmeticsNot Available
CEDs000492Cell phones?Cell phones contain a variety of synthetic chemicals and materials, including plastics, metals, and glass, which can contribute to environmental contamination.Electrical & Electronic EquipmentNot Available
CEDs000493Capacitors?Capacitors are electronic components that store and release electrical energy, often using dielectric materials that can include synthetic chemicals.Electrical & Electronic EquipmentNot Available
Pathways
0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Corticosteroid-binding globulin structureClick to view 3D structureCorticosteroid-binding globulinP08185HumansPredicted (SEA)
Prediction Confidence Score
0.569
Applicability Domain
0.706
Statistical Significance
5.00e-05
Supporting Reference Compounds
21
E-value
0.389246
Androgen receptor structureClick to view 3D structureAndrogen receptorP15207Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.557
Applicability Domain
0.706
Statistical Significance
2.20e-04
Supporting Reference Compounds
73
E-value
1.71268
Sex hormone-binding globulin structureClick to view 3D structureSex hormone-binding globulinP04278HumansPredicted (SEA)
Prediction Confidence Score
0.552
Applicability Domain
0.706
Statistical Significance
1.10e-04
Supporting Reference Compounds
33
E-value
0.856341
Mineralocorticoid receptor structureClick to view 3D structureMineralocorticoid receptorP08235HumansPredicted (SEA)
Prediction Confidence Score
0.496
Applicability Domain
0.706
Statistical Significance
2.70e-04
Supporting Reference Compounds
74
E-value
2.10193
Glucocorticoid receptor structureClick to view 3D structureGlucocorticoid receptorP04150HumansPredicted (SEA)
Prediction Confidence Score
0.488
Applicability Domain
0.706
Statistical Significance
9.50e-04
Supporting Reference Compounds
154
E-value
7.39568
Click to view 3D structureProgesterone receptorQ690N0Bos taurusPredicted (SEA)
Prediction Confidence Score
0.488
Applicability Domain
0.706
Statistical Significance
2.00e-04
Supporting Reference Compounds
40
E-value
1.55698
Androgen receptor structureClick to view 3D structureAndrogen receptorP10275HumansPredicted (SEA)
Prediction Confidence Score
0.486
Applicability Domain
0.706
Statistical Significance
9.20e-04
Supporting Reference Compounds
146
E-value
7.16213
Androgen receptor structureClick to view 3D structureAndrogen receptorP19091Mus musculusPredicted (SEA)
Prediction Confidence Score
0.478
Applicability Domain
0.706
Statistical Significance
5.00e-05
Supporting Reference Compounds
19
E-value
0.389246
G-protein coupled bile acid receptor 1 structureClick to view 3D structureG-protein coupled bile acid receptor 1Q8TDU6HumansPredicted (SEA)
Prediction Confidence Score
0.461
Applicability Domain
0.706
Statistical Significance
0.0013
Supporting Reference Compounds
54
E-value
10.3539
Estrogen receptor structureClick to view 3D structureEstrogen receptorP03372HumansPredicted (SEA)
Prediction Confidence Score
0.438
Applicability Domain
0.706
Statistical Significance
0.0016
Supporting Reference Compounds
201
E-value
12.2223
3-oxo-5-alpha-steroid 4-dehydrogenase 2 structureClick to view 3D structure3-oxo-5-alpha-steroid 4-dehydrogenase 2P31213HumansPredicted (SEA)
Prediction Confidence Score
0.437
Applicability Domain
0.561
Statistical Significance
2.50e-04
Supporting Reference Compounds
19
E-value
1.94623
Click to view 3D structureSolute carrier family 22 member 3O88446Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.43
Applicability Domain
0.552
Statistical Significance
5.00e-05
Supporting Reference Compounds
3
E-value
0.389246
Click to view 3D structure3-oxo-5-alpha-steroid 4-dehydrogenase 1P18405HumansPredicted (SEA)
Prediction Confidence Score
0.424
Applicability Domain
0.561
Statistical Significance
2.50e-04
Supporting Reference Compounds
14
E-value
1.94623
Progesterone receptor structureClick to view 3D structureProgesterone receptorP06401HumansPredicted (SEA)
Prediction Confidence Score
0.423
Applicability Domain
0.706
Statistical Significance
0.0015
Supporting Reference Compounds
119
E-value
11.7552
Steroid 17-alpha-hydroxylase/17,20 lyase structureClick to view 3D structureSteroid 17-alpha-hydroxylase/17,20 lyaseP05093HumansPredicted (SEA)
Prediction Confidence Score
0.42
Applicability Domain
0.561
Statistical Significance
6.70e-04
Supporting Reference Compounds
69
E-value
5.2159
Click to view 3D structure11-beta-hydroxysteroid dehydrogenase type 2P80365HumansPredicted (SEA)
Prediction Confidence Score
0.41
Applicability Domain
0.569
Statistical Significance
2.70e-04
Supporting Reference Compounds
32
E-value
2.10193
Sigma non-opioid intracellular receptor 1 structureClick to view 3D structureSigma non-opioid intracellular receptor 1Q99720HumansPredicted (SEA)
Prediction Confidence Score
0.393
Applicability Domain
0.706
Statistical Significance
0.013
Supporting Reference Compounds
562
E-value
101.593
Click to view 3D structureSolute carrier organic anion transporter family member 1A1P46720Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.392
Applicability Domain
0.527
Statistical Significance
1.70e-04
Supporting Reference Compounds
10
E-value
1.32344
Aldo-keto reductase family 1 member B10 structureClick to view 3D structureAldo-keto reductase family 1 member B10O60218HumansPredicted (SEA)
Prediction Confidence Score
0.389
Applicability Domain
0.5
Statistical Significance
0.0011
Supporting Reference Compounds
49
E-value
8.32987
Click to view 3D structureSolute carrier family 22 member 2Q9R0W2Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.381
Applicability Domain
0.706
Statistical Significance
2.00e-05
Supporting Reference Compounds
14
E-value
0.155698
Aromatase structureClick to view 3D structureAromataseP11511HumansPredicted (SEA)
Prediction Confidence Score
0.38
Applicability Domain
0.527
Statistical Significance
0.0025
Supporting Reference Compounds
127
E-value
19.1509
Click to view 3D structureC-8 sterol isomerase ERG2P32352Baker's yeastPredicted (SEA)
Prediction Confidence Score
0.367
Applicability Domain
0.706
Statistical Significance
1.00e-04
Supporting Reference Compounds
20
E-value
0.778492
Cytochrome P450 2C9 structureClick to view 3D structureCytochrome P450 2C9P11712HumansPredicted (SEA)
Prediction Confidence Score
0.367
Applicability Domain
0.706
Statistical Significance
0.0316
Supporting Reference Compounds
1245
E-value
246.004
Click to view 3D structure3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1P14060HumansPredicted (SEA)
Prediction Confidence Score
0.363
Applicability Domain
0.4
Statistical Significance
2.30e-04
Supporting Reference Compounds
3
E-value
1.79053
11-beta-hydroxysteroid dehydrogenase 1 structureClick to view 3D structure11-beta-hydroxysteroid dehydrogenase 1P28845HumansPredicted (SEA)
Prediction Confidence Score
0.363
Applicability Domain
0.569
Statistical Significance
0.0015
Supporting Reference Compounds
76
E-value
11.366
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available