Reduced_haloperidol (CED0014621)

Record Information
Version1.0
Creation Date2026-04-06 09:27:09 UTC
Update Date2026-05-21 10:17:32 UTC
SynCED IDCED0014621
Secondary Accession Numbers
  • CHEM121612
Identification
Common NameReduced_haloperidol
ClassSmall Molecule
Description
Reduced_haloperidol belongs to the phenylpiperidines, a subclass of piperidines within the organic compounds. This substance is categorized as an organoheterocyclic compound. Reduced_haloperidol is identified as being found in or released from 13 recorded sources across several sectors. Within electrical and electronic equipment, it is associated with capacitors, batteries, printed circuit boards, wires and cables, cell phones, and one additional source. In the textiles, leather and furnishings sector, it is found in carpets, rugs, and synthetic textiles. It is also linked to food packaging within the food, food processing and cookware sector, and medical devices within the healthcare, pharmaceuticals and veterinary products sector. Additionally, it is found in lubricants used in both energy, oil and gas as well as industrial manufacturing and chemical processing, along with one other sector. Recorded exposure routes for this compound include oral, inhalation, and touch.
Contaminant Type
  • PFAS
Chemical Structure
MOLSDFPDBSMILESInChI
SynonymsNot Available
Chemical FormulaNot Available
Average Molecular MassNot Available
Monoisotopic MassNot Available
CAS Registry Number136271-61-9
IUPAC NameNot Available
Traditional NameNot Available
SMILESNot Available
InChI IdentifierInChI=1S/C21H25ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,20,25-26H,1-2,11-15H2/t20-/m0/s1
InChI KeyWNZBBTJFOIOEMP-FQEVSTJZSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Toxicity ValuesNot Available
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionDescriptionReference
Exposure Sources
Source IDSourceSectorReference
CEDs000007Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.Agriculture & land managementNot Available
CEDs000120Wires and cables?Wires and cables are integral components in the transmission of electrical power and signals.Electrical & Electronic EquipmentNot Available
CEDs000121Printed circuit boards?Printed circuit boards (PCBs) are essential components in the manufacturing of electronic devices, serving as the backbone for electrical connections and circuit pathways.Electrical & Electronic EquipmentNot Available
CEDs000125Batteries?Batteries are devices that store and release electrical energy through electrochemical reactions.Electrical & Electronic EquipmentNot Available
CEDs000130Semiconductors?Semiconductors are materials that possess electrical conductivity between that of conductors and insulators, making them essential for various electronic applications, including transistors, diodes, and integrated circuits.Electrical & Electronic EquipmentNot Available
CEDs000138Lubricants?Lubricants are synthetic or petroleum-derived substances used to reduce friction between surfaces in machinery and equipment, enhancing operational efficiency and longevity.Energy, oil & gasNot Available
CEDs000147Food packaging?Food packaging often utilizes synthetic chemicals, such as plastics and coatings, to enhance durability, moisture resistance, and shelf life.Food, food processing & cookwareNot Available
CEDs000174Lubricants?Lubricants are synthetic or petroleum-based substances used to reduce friction and wear between moving parts in machinery and equipment.Industrial manufacturing & chemical processingNot Available
CEDs000234Medical devices?Medical devices often incorporate synthetic chemicals in their manufacturing processes, which can contribute to contamination in healthcare settings.Healthcare, pharmaceuticals & veterinary productsNot Available
CEDs000451Carpets and Rugs?Carpets and rugs are commonly manufactured using synthetic fibers such as nylon, polyester, and polypropylene, which can be derived from petrochemical sources.Textiles, leather & furnishingsNot Available
CEDs000454Synthetic textiles?Synthetic textiles are materials derived from man-made fibers, such as polyester, nylon, and acrylic, which are produced through chemical processes involving petrochemicals.Textiles, leather & furnishingsNot Available
CEDs000490Personal care & cosmeticsNot Available
CEDs000492Cell phones?Cell phones contain a variety of synthetic chemicals and materials, including plastics, metals, and glass, which can contribute to environmental contamination.Electrical & Electronic EquipmentNot Available
CEDs000493Capacitors?Capacitors are electronic components that store and release electrical energy, often using dielectric materials that can include synthetic chemicals.Electrical & Electronic EquipmentNot Available
Pathways
0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
5-hydroxytryptamine receptor 6 structureClick to view 3D structure5-hydroxytryptamine receptor 6P50406HumansPredicted (SEA)
Prediction Confidence Score
0.541
Applicability Domain
0.635
Statistical Significance
0.0011
Supporting Reference Compounds
536
E-value
8.25202
N-acetyltransferase Eis structureClick to view 3D structureN-acetyltransferase EisP9WFK7Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Predicted (SEA)
Prediction Confidence Score
0.522
Applicability Domain
0.635
Statistical Significance
1.10e-04
Supporting Reference Compounds
7
E-value
0.856341
Alpha-2B adrenergic receptor structureClick to view 3D structureAlpha-2B adrenergic receptorP18089HumansPredicted (SEA)
Prediction Confidence Score
0.517
Applicability Domain
0.635
Statistical Significance
6.20e-04
Supporting Reference Compounds
340
E-value
4.82665
D(2) dopamine receptor structureClick to view 3D structureD(2) dopamine receptorP14416HumansPredicted (SEA)
Prediction Confidence Score
0.794
Applicability Domain
1.0
Statistical Significance
9.00e-05
Supporting Reference Compounds
1103
E-value
0.700643
Click to view 3D structureD(2) dopamine receptorP61169RatPredicted (SEA)
Prediction Confidence Score
0.746
Applicability Domain
1.0
Statistical Significance
2.30e-04
Supporting Reference Compounds
528
E-value
1.79053
Click to view 3D structureSigma non-opioid intracellular receptor 1Q60492Cavia porcellusPredicted (SEA)
Prediction Confidence Score
0.746
Applicability Domain
1.0
Statistical Significance
3.00e-05
Supporting Reference Compounds
229
E-value
0.233548
Sigma non-opioid intracellular receptor 1 structureClick to view 3D structureSigma non-opioid intracellular receptor 1Q99720HumansPredicted (SEA)
Prediction Confidence Score
0.727
Applicability Domain
1.0
Statistical Significance
9.00e-05
Supporting Reference Compounds
562
E-value
0.700643
D(3) dopamine receptor structureClick to view 3D structureD(3) dopamine receptorP35462HumansPredicted (SEA)
Prediction Confidence Score
0.711
Applicability Domain
1.0
Statistical Significance
4.60e-04
Supporting Reference Compounds
861
E-value
3.58106
Click to view 3D structureD(3) dopamine receptorP19020Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.705
Applicability Domain
1.0
Statistical Significance
1.30e-04
Supporting Reference Compounds
145
E-value
1.01204
Histamine H1 receptor structureClick to view 3D structureHistamine H1 receptorP35367HumansPredicted (SEA)
Prediction Confidence Score
0.622
Applicability Domain
0.673
Statistical Significance
3.70e-04
Supporting Reference Compounds
507
E-value
2.88042
5-hydroxytryptamine receptor 2A structureClick to view 3D structure5-hydroxytryptamine receptor 2AP28223HumansPredicted (SEA)
Prediction Confidence Score
0.622
Applicability Domain
0.673
Statistical Significance
8.30e-04
Supporting Reference Compounds
955
E-value
6.46149
5-hydroxytryptamine receptor 1A structureClick to view 3D structure5-hydroxytryptamine receptor 1AP08908HumansPredicted (SEA)
Prediction Confidence Score
0.622
Applicability Domain
0.673
Statistical Significance
0.0015
Supporting Reference Compounds
953
E-value
11.4438
Sodium-dependent serotonin transporter structureClick to view 3D structureSodium-dependent serotonin transporterP31645HumansPredicted (SEA)
Prediction Confidence Score
0.621
Applicability Domain
0.673
Statistical Significance
5.80e-04
Supporting Reference Compounds
593
E-value
4.51525
5-hydroxytryptamine receptor 7 structureClick to view 3D structure5-hydroxytryptamine receptor 7P34969HumansPredicted (SEA)
Prediction Confidence Score
0.621
Applicability Domain
0.673
Statistical Significance
5.10e-04
Supporting Reference Compounds
565
E-value
3.97031
D(1B) dopamine receptor structureClick to view 3D structureD(1B) dopamine receptorP21918HumansPredicted (SEA)
Prediction Confidence Score
0.621
Applicability Domain
0.673
Statistical Significance
8.00e-05
Supporting Reference Compounds
209
E-value
0.622794
D(1A) dopamine receptor structureClick to view 3D structureD(1A) dopamine receptorP21728HumansPredicted (SEA)
Prediction Confidence Score
0.621
Applicability Domain
0.673
Statistical Significance
6.60e-04
Supporting Reference Compounds
425
E-value
5.13805
Sodium-dependent noradrenaline transporter structureClick to view 3D structureSodium-dependent noradrenaline transporterP23975HumansPredicted (SEA)
Prediction Confidence Score
0.621
Applicability Domain
0.673
Statistical Significance
2.50e-04
Supporting Reference Compounds
451
E-value
1.94623
5-hydroxytryptamine receptor 2B structureClick to view 3D structure5-hydroxytryptamine receptor 2BP41595HumansPredicted (SEA)
Prediction Confidence Score
0.621
Applicability Domain
0.673
Statistical Significance
4.00e-04
Supporting Reference Compounds
686
E-value
3.11397
Click to view 3D structureSigma intracellular receptor 2Q5U3Y7Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.57
Applicability Domain
1.0
Statistical Significance
2.20e-04
Supporting Reference Compounds
110
E-value
1.71268
Click to view 3D structureD(4) dopamine receptorP30729Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.56
Applicability Domain
0.673
Statistical Significance
1.30e-04
Supporting Reference Compounds
92
E-value
1.01204
5-hydroxytryptamine receptor 2C structureClick to view 3D structure5-hydroxytryptamine receptor 2CP28335HumansPredicted (SEA)
Prediction Confidence Score
0.56
Applicability Domain
0.635
Statistical Significance
0.0015
Supporting Reference Compounds
823
E-value
11.7552
D(4) dopamine receptor structureClick to view 3D structureD(4) dopamine receptorP21917HumansPredicted (SEA)
Prediction Confidence Score
0.56
Applicability Domain
0.635
Statistical Significance
0.0014
Supporting Reference Compounds
524
E-value
11.2881
Sodium-dependent dopamine transporter structureClick to view 3D structureSodium-dependent dopamine transporterQ01959HumansPredicted (SEA)
Prediction Confidence Score
0.546
Applicability Domain
0.66
Statistical Significance
8.60e-04
Supporting Reference Compounds
506
E-value
6.69503
Mu-type opioid receptor structureClick to view 3D structureMu-type opioid receptorP35372HumansPredicted (SEA)
Prediction Confidence Score
0.543
Applicability Domain
0.635
Statistical Significance
0.0061
Supporting Reference Compounds
527
E-value
47.1766
Histamine H2 receptor structureClick to view 3D structureHistamine H2 receptorP25021HumansPredicted (SEA)
Prediction Confidence Score
0.543
Applicability Domain
0.635
Statistical Significance
3.10e-04
Supporting Reference Compounds
256
E-value
2.41333
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available