R-2-Hydroxyibuprofen (CED0118506)

Record Information
Version1.0
Creation Date2026-04-06 09:30:44 UTC
Update Date2026-05-21 10:23:59 UTC
Accession NumberCHEM121688
Identification
Common NameR-2-Hydroxyibuprofen
ClassSmall Molecule
Description
R-2-Hydroxyibuprofen belongs to the phenylpropanoic acids, a class of phenylpropanoids and polyketides within the organic compounds. This compound is associated with 13 recorded sources across multiple sectors. Within electrical and electronic equipment, it is found in cell phones, capacitors, batteries, printed circuit boards, wires and cables, and one additional source. It is also present in food packaging within the food, food processing and cookware sector. In the healthcare, pharmaceuticals and veterinary products sector, it is found in medical devices. Further sources include lubricants used in energy, oil and gas, as well as industrial manufacturing and chemical processing. Additionally, it is found in synthetic textiles, carpets, and rugs within the textiles, leather and furnishings sector, and one other sector. Human exposure to R-2-Hydroxyibuprofen occurs through several recorded routes, including inhalation, oral ingestion, and touch.
Contaminant Type
  • PFAS
Chemical Structure
SynonymsNot Available
Chemical FormulaNot Available
Average Molecular MassNot Available
Monoisotopic MassNot Available
CAS Registry NumberNot Available
IUPAC NameNot Available
Traditional NameNot Available
SMILESNot Available
InChI IdentifierInChI=1S/C13H18O3/c1-9(12(14)15)11-6-4-10(5-7-11)8-13(2,3)16/h4-7,9,16H,8H2,1-3H3,(H,14,15)/t9-/m1/s1
InChI KeyUJHKVYPPCJBOSG-SECBINFHSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity Values
Toxicity ValueUnitValue RangeOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalReference
1180.0Log mg/kg[660:2100]RatLD50oralpredictedNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
7PesticidesAgriculture & land managementNot Available
120Wires and cablesElectrical & Electronic EquipmentNot Available
121Printed circuit boardsElectrical & Electronic EquipmentNot Available
125BatteriesElectrical & Electronic EquipmentNot Available
130SemiconductorsElectrical & Electronic EquipmentNot Available
138LubricantsEnergy, oil & gasNot Available
147Food packagingFood, food processing & cookwareNot Available
174LubricantsIndustrial manufacturing & chemical processingNot Available
234Medical devicesHealthcare, pharmaceuticals & veterinary productsNot Available
451Carpets and RugsTextiles, leather & furnishingsNot Available
454Synthetic textilesTextiles, leather & furnishingsNot Available
490Personal care & cosmeticsNot Available
492Cell phonesElectrical & Electronic EquipmentNot Available
493CapacitorsElectrical & Electronic EquipmentNot Available
Pathways
0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Prostaglandin G/H synthase 1 structureClick to view 3D structureProstaglandin G/H synthase 1P23219HumansPredicted (SEA)2.88042
Prostaglandin G/H synthase 2 structureClick to view 3D structureProstaglandin G/H synthase 2P35354HumansPredicted (SEA)5.13805
Click to view 3D structureProstaglandin G/H synthase 1P05979Ovis ariesPredicted (SEA)2.95827
Click to view 3D structureProstaglandin G/H synthase 2P79208Ovis ariesPredicted (SEA)0.389246
Aldo-keto reductase family 1 member C3 structureClick to view 3D structureAldo-keto reductase family 1 member C3P42330HumansPredicted (SEA)6.15009
Click to view 3D structureSolute carrier family 22 member 6Q4U2R8HumansPredicted (SEA)0.778492
Epidermal growth factor receptor structureClick to view 3D structureEpidermal growth factor receptorP00533HumansPredicted (SEA)384.419
Aldo-keto reductase family 1 member C2 structureClick to view 3D structureAldo-keto reductase family 1 member C2P52895HumansPredicted (SEA)10.4318
Click to view 3D structureSolute carrier family 22 member 6O35956Rattus norvegicusPredicted (SEA)0.155698
Click to view 3D structureProstaglandin G/H synthase 1Q63921Rattus norvegicusPredicted (SEA)1.08989
Click to view 3D structureProstaglandin G/H synthase 2Q05769Mus musculusPredicted (SEA)13.4679
Click to view 3D structureLeukotriene A-4 hydrolaseP19602Cavia porcellusPredicted (SEA)2.95827
Click to view 3D structureSolute carrier family 22 member 20Q80UJ1Mus musculusPredicted (SEA)0.0778492
Angiotensin-converting enzyme structureClick to view 3D structureAngiotensin-converting enzymeP12821HumansPredicted (SEA)243.045
Replicase polyprotein 1ab structureClick to view 3D structureReplicase polyprotein 1abP0DTD1SARS-CoV-2Predicted (SEA)241.021
Click to view 3D structureFatty acid-binding protein, liverP02692Rattus norvegicusPredicted (SEA)3.42537
Polyunsaturated fatty acid 5-lipoxygenase structureClick to view 3D structurePolyunsaturated fatty acid 5-lipoxygenaseP09917HumansPredicted (SEA)214.942
Aldo-keto reductase family 1 member B1 structureClick to view 3D structureAldo-keto reductase family 1 member B1P15121HumansPredicted (SEA)106.031
Click to view 3D structureAngiotensin-converting enzymeP12822Oryctolagus cuniculusPredicted (SEA)148.069
Click to view 3D structureCytosol aminopeptidaseP00727Bos taurusPredicted (SEA)97.078
Tyrosine-protein kinase Fyn structureClick to view 3D structureTyrosine-protein kinase FynP06241HumansPredicted (SEA)1527.09
Cytochrome P450 2C9 structureClick to view 3D structureCytochrome P450 2C9P11712HumansPredicted (SEA)2659.49
72 kDa type IV collagenase structureClick to view 3D structure72 kDa type IV collagenaseP08253HumansPredicted (SEA)789.391
Click to view 3D structureAminopeptidase BQ8VCT3Mus musculusPredicted (SEA)55.1172
Click to view 3D structurePolyunsaturated fatty acid 5-lipoxygenaseP12527Rattus norvegicusPredicted (SEA)124.014
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available