Cyclosporine_a (CED0001017)

Record Information
Version1.0
Creation Date2026-04-06 09:56:54 UTC
Update Date2026-05-21 12:38:10 UTC
Accession NumberCHEM122256
Identification
Common NameCyclosporine_a
ClassSmall Molecule
Description
Cyclosporine_a belongs to the peptoid-peptide hybrids, a subclass of peptidomimetics within the organic compounds. It is categorized under the superclass of organic acids and derivatives. The compound has been identified in 13 recorded sources across several sectors. Within the healthcare, pharmaceuticals & veterinary products sector, it is found in medical devices. In the energy, oil & gas and industrial manufacturing & chemical processing sectors, it is present in lubricants. It is also found in food packaging within the food, food processing & cookware sector. In the textiles, leather & furnishings sector, it is associated with carpets, rugs, and synthetic textiles. Furthermore, it is released from electrical & electronic equipment, including cell phones, capacitors, batteries, wires and cables, and printed circuit boards, among one other source. There is one additional sector where the compound is recorded. Recorded exposure routes for Cyclosporine_a include inhalation, oral, and touch.
Contaminant Type
  • PFAS
Chemical Structure
SynonymsNot Available
Chemical FormulaNot Available
Average Molecular MassNot Available
Monoisotopic MassNot Available
CAS Registry NumberNot Available
IUPAC NameNot Available
Traditional NameNot Available
SMILESNot Available
InChI IdentifierInChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41-,42+,43-,44-,45-,46+,47+,49+,50+,51-,52-/m1/s1
InChI KeyPMATZTZNYRCHOR-UITTWSBISA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity ValuesNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
7PesticidesAgriculture & land managementNot Available
120Wires and cablesElectrical & Electronic EquipmentNot Available
121Printed circuit boardsElectrical & Electronic EquipmentNot Available
125BatteriesElectrical & Electronic EquipmentNot Available
130SemiconductorsElectrical & Electronic EquipmentNot Available
138LubricantsEnergy, oil & gasNot Available
147Food packagingFood, food processing & cookwareNot Available
174LubricantsIndustrial manufacturing & chemical processingNot Available
234Medical devicesHealthcare, pharmaceuticals & veterinary productsNot Available
451Carpets and RugsTextiles, leather & furnishingsNot Available
454Synthetic textilesTextiles, leather & furnishingsNot Available
490Personal care & cosmeticsNot Available
492Cell phonesElectrical & Electronic EquipmentNot Available
493CapacitorsElectrical & Electronic EquipmentNot Available
Pathways
0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureInterleukin-2P04351Mus musculusPredicted (SEA)2.17978
Peptidyl-prolyl cis-trans isomerase A structureClick to view 3D structurePeptidyl-prolyl cis-trans isomerase AP62937HumansPredicted (SEA)2.25763
Peptidyl-prolyl cis-trans isomerase B structureClick to view 3D structurePeptidyl-prolyl cis-trans isomerase BP23284HumansPredicted (SEA)2.33548
ATP-dependent translocase ABCB1 structureClick to view 3D structureATP-dependent translocase ABCB1P08183HumansPredicted (SEA)4.5931
Peptidyl-prolyl cis-trans isomerase F, mitochondrial structureClick to view 3D structurePeptidyl-prolyl cis-trans isomerase F, mitochondrialP30405HumansPredicted (SEA)2.25763
Solute carrier organic anion transporter family member 1B1 structureClick to view 3D structureSolute carrier organic anion transporter family member 1B1Q9Y6L6HumansPredicted (SEA)2.88042
Solute carrier organic anion transporter family member 1B3 structureClick to view 3D structureSolute carrier organic anion transporter family member 1B3Q9NPD5HumansPredicted (SEA)2.64687
Bile salt export pump structureClick to view 3D structureBile salt export pumpO95342HumansPredicted (SEA)3.58106
Peptidyl-prolyl cis-trans isomerase C structureClick to view 3D structurePeptidyl-prolyl cis-trans isomerase CP45877HumansPredicted (SEA)2.33548
Protein phosphatase 3 catalytic subunit alpha structureClick to view 3D structureProtein phosphatase 3 catalytic subunit alphaQ08209HumansPredicted (SEA)3.11397
Reverse transcriptase/RNaseH structureClick to view 3D structureReverse transcriptase/RNaseHQ72547Human immunodeficiency virus 1Predicted (SEA)23.5883
Broad substrate specificity ATP-binding cassette transporter ABCG2 structureClick to view 3D structureBroad substrate specificity ATP-binding cassette transporter ABCG2Q9UNQ0HumansPredicted (SEA)180.766
fMet-Leu-Phe receptor structureClick to view 3D structurefMet-Leu-Phe receptorP21462HumansPredicted (SEA)56.1293
Peptidyl-prolyl cis-trans isomerase FKBP1B structureClick to view 3D structurePeptidyl-prolyl cis-trans isomerase FKBP1BP68106HumansPredicted (SEA)4.9045
Cytochrome P450 3A4 structureClick to view 3D structureCytochrome P450 3A4P08684HumansPredicted (SEA)4868.85
Hepatic sodium/bile acid cotransporter structureClick to view 3D structureHepatic sodium/bile acid cotransporterQ14973HumansPredicted (SEA)31.3732
Click to view 3D structureATP-dependent Clp protease ATP-binding subunit ClpC1P9WPC9Mycobacterium tuberculosisPredicted (SEA)20.0072
Peptidyl-prolyl cis-trans isomerase FKBP1A structureClick to view 3D structurePeptidyl-prolyl cis-trans isomerase FKBP1AP62942HumansPredicted (SEA)148.77
Substance-K receptor structureClick to view 3D structureSubstance-K receptorP21452HumansPredicted (SEA)2055.69
Click to view 3D structureAureobasidin-resistance proteinQ9Y745Neosartorya fumigata (Aspergillus fumigatus)Predicted (SEA)47.2545
Cytochrome P450 2C19 structureClick to view 3D structureCytochrome P450 2C19P33261HumansPredicted (SEA)6435.09
Click to view 3D structurePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformQ9JHG7Mus musculusPredicted (SEA)127.673
Multidrug resistance-associated protein 1 structureClick to view 3D structureMultidrug resistance-associated protein 1P33527HumansPredicted (SEA)1331.61
Click to view 3D structureATP-dependent translocase ABCB1P06795Mus musculusPredicted (SEA)655.958
Click to view 3D structureATP-dependent translocase ABCB1P21447Mus musculusPredicted (SEA)189.563
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available