Np-nitrosonornicotine, N-glucuronide (CED0146963)

Record Information

Version

1.0

Creation Date

2026-04-06 09:57:05 UTC

Update Date

2026-05-21 12:38:30 UTC

SynCED ID

CED0146963

Secondary Accession Numbers

CHEM122260

Identification

Common Name

Np-nitrosonornicotine, N-glucuronide

Class

Small Molecule

Description

Np-nitrosonornicotine, N-glucuronide is a compound identified in 13 recorded sources across multiple sectors. Within the Electrical & Electronic Equipment sector, it is found in or released from cell phones, capacitors, wires and cables, batteries, and printed circuit boards, among others. It is also associated with the Textiles, leather & furnishings sector, specifically in synthetic textiles as well as carpets and rugs. The compound is present in food packaging within the Food, food processing & cookware sector. In the healthcare, pharmaceuticals & veterinary products sector, it is linked to medical devices. Additionally, Np-nitrosonornicotine, N-glucuronide is found in lubricants used in both the Energy, oil & gas sector and the Industrial manufacturing & chemical processing sector. It has been identified in one additional sector. Recorded routes of exposure for this compound include inhalation, oral, and touch.

Contaminant Type

PFAS

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

Not Available

Average Molecular Mass

Not Available

Monoisotopic Mass

Not Available

CAS Registry Number

Not Available

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

Not Available

InChI Identifier

InChI=1S/C15H19N3O7/c19-10-11(20)13(15(22)23)25-14(12(10)21)17-5-1-3-8(7-17)9-4-2-6-18(9)16-24/h1,3,5,7,9-14,19-21H,2,4,6H2/p+1/t9?,10-,11-,12+,13-,14?/m0/s1

InChI Key

PSJRIZSDTBSS-GRTDBQQJSA-O

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
5318.0 Log mg/kg [3000:9500]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Description	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000007	Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.	Agriculture & land management	Not Available
CEDs000120	Wires and cables?Wires and cables are integral components in the transmission of electrical power and signals.	Electrical & Electronic Equipment	Not Available
CEDs000121	Printed circuit boards?Printed circuit boards (PCBs) are essential components in the manufacturing of electronic devices, serving as the backbone for electrical connections and circuit pathways.	Electrical & Electronic Equipment	Not Available
CEDs000125	Batteries?Batteries are devices that store and release electrical energy through electrochemical reactions.	Electrical & Electronic Equipment	Not Available
CEDs000130	Semiconductors?Semiconductors are materials that possess electrical conductivity between that of conductors and insulators, making them essential for various electronic applications, including transistors, diodes, and integrated circuits.	Electrical & Electronic Equipment	Not Available
CEDs000138	Lubricants?Lubricants are synthetic or petroleum-derived substances used to reduce friction between surfaces in machinery and equipment, enhancing operational efficiency and longevity.	Energy, oil & gas	Not Available
CEDs000147	Food packaging?Food packaging often utilizes synthetic chemicals, such as plastics and coatings, to enhance durability, moisture resistance, and shelf life.	Food, food processing & cookware	Not Available
CEDs000174	Lubricants?Lubricants are synthetic or petroleum-based substances used to reduce friction and wear between moving parts in machinery and equipment.	Industrial manufacturing & chemical processing	Not Available
CEDs000234	Medical devices?Medical devices often incorporate synthetic chemicals in their manufacturing processes, which can contribute to contamination in healthcare settings.	Healthcare, pharmaceuticals & veterinary products	Not Available
CEDs000451	Carpets and Rugs?Carpets and rugs are commonly manufactured using synthetic fibers such as nylon, polyester, and polypropylene, which can be derived from petrochemical sources.	Textiles, leather & furnishings	Not Available
CEDs000454	Synthetic textiles?Synthetic textiles are materials derived from man-made fibers, such as polyester, nylon, and acrylic, which are produced through chemical processes involving petrochemicals.	Textiles, leather & furnishings	Not Available
CEDs000490		Personal care & cosmetics	Not Available
CEDs000492	Cell phones?Cell phones contain a variety of synthetic chemicals and materials, including plastics, metals, and glass, which can contribute to environmental contamination.	Electrical & Electronic Equipment	Not Available
CEDs000493	Capacitors?Capacitors are electronic components that store and release electrical energy, often using dielectric materials that can include synthetic chemicals.	Electrical & Electronic Equipment	Not Available

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Alpha-L-iduronidase	P35475	Humans	Predicted (SEA)	Prediction Confidence Score 0.244 Applicability Domain 0.244 Low confidence Statistical Significance 8.40e-04 Supporting Reference Compounds 1 E-value 6.53933
Click to view 3D structure	Vesicular acetylcholine transporter	Q16572	Humans	Predicted (SEA)	Prediction Confidence Score 0.235 Applicability Domain 0.238 Low confidence Statistical Significance 0.0182 Supporting Reference Compounds 23 E-value 141.374
Click to view 3D structure	Lycopene beta-cyclase	P21687	Pantoea ananas	Predicted (SEA)	Prediction Confidence Score 0.234 Applicability Domain 0.234 Low confidence Statistical Significance 0.005 Supporting Reference Compounds 1 E-value 38.8468
Click to view 3D structure	Sigma non-opioid intracellular receptor 1	Q9R0C9	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.233 Applicability Domain 0.238 Low confidence Statistical Significance 0.1282 Supporting Reference Compounds 207 E-value 997.871
Click to view 3D structure	Vesicular acetylcholine transporter	Q62666	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.232 Applicability Domain 0.238 Low confidence Statistical Significance 0.0138 Supporting Reference Compounds 21 E-value 107.743
Click to view 3D structure	Sodium-dependent dopamine transporter	P23977	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.231 Applicability Domain 0.254 Low confidence Statistical Significance 0.1228 Supporting Reference Compounds 203 E-value 955.677
Click to view 3D structure	Sigma non-opioid intracellular receptor 1	Q99720	Humans	Predicted (SEA)	Prediction Confidence Score 0.23 Applicability Domain 0.238 Low confidence Statistical Significance 0.3756 Supporting Reference Compounds 562 E-value 2923.78
Click to view 3D structure	D(2) dopamine receptor	P61169	Rat	Predicted (SEA)	Prediction Confidence Score 0.23 Applicability Domain 0.254 Low confidence Statistical Significance 0.3 Supporting Reference Compounds 528 E-value 2335.87
Click to view 3D structure	2-dehydropantoate 2-reductase	P0A9J4	Escherichia coli K-12	Predicted (SEA)	Prediction Confidence Score 0.226 Applicability Domain 0.226 Low confidence Statistical Significance 0.0044 Supporting Reference Compounds 2 E-value 34.4872
Click to view 3D structure	Vesicular acetylcholine transporter	P81721	Torpedo californica	Predicted (SEA)	Prediction Confidence Score 0.225 Applicability Domain 0.238 Low confidence Statistical Significance 0.0091 Supporting Reference Compounds 10 E-value 71.1542
Click to view 3D structure	Sodium-dependent serotonin transporter	P31652	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.224 Applicability Domain 0.254 Low confidence Statistical Significance 0.2264 Supporting Reference Compounds 297 E-value 1762.66
Click to view 3D structure	Norepinephrine transporter	Q9WTR4	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.221 Applicability Domain 0.254 Low confidence Statistical Significance 0.0901 Supporting Reference Compounds 112 E-value 701.811
Click to view 3D structure	Collagenase 3	P45452	Humans	Predicted (SEA)	Prediction Confidence Score 0.218 Applicability Domain 0.244 Low confidence Statistical Significance 0.3339 Supporting Reference Compounds 269 E-value 2599.46
Click to view 3D structure	Disintegrin and metalloproteinase domain-containing protein 17	P78536	Humans	Predicted (SEA)	Prediction Confidence Score 0.217 Applicability Domain 0.244 Low confidence Statistical Significance 0.2675 Supporting Reference Compounds 166 E-value 2082.31
Click to view 3D structure	D(1A) dopamine receptor	P18901	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.216 Applicability Domain 0.25 Low confidence Statistical Significance 0.2272 Supporting Reference Compounds 206 E-value 1768.81
Click to view 3D structure	D(3) dopamine receptor	P35462	Humans	Predicted (SEA)	Prediction Confidence Score 0.215 Applicability Domain 0.239 Low confidence Statistical Significance 0.6258 Supporting Reference Compounds 861 E-value 4872.19
Click to view 3D structure	Sodium- and chloride-dependent GABA transporter 1	P30531	Humans	Predicted (SEA)	Prediction Confidence Score 0.215 Applicability Domain 0.233 Low confidence Statistical Significance 0.0072 Supporting Reference Compounds 8 E-value 56.1293
Click to view 3D structure	Sodium- and chloride-dependent GABA transporter 1	P31648	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.214 Applicability Domain 0.233 Low confidence Statistical Significance 0.0255 Supporting Reference Compounds 17 E-value 198.204
Click to view 3D structure	D(2) dopamine receptor	P14416	Humans	Predicted (SEA)	Prediction Confidence Score 0.214 Applicability Domain 0.227 Low confidence Statistical Significance 0.6834 Supporting Reference Compounds 1103 E-value 5320.14
Click to view 3D structure	Cytochrome P450 3A4	P08684	Humans	Predicted (SEA)	Prediction Confidence Score 0.214 Applicability Domain 0.217 Low confidence Statistical Significance 0.892 Supporting Reference Compounds 1538 E-value 6944.38
Click to view 3D structure	Lysine-specific histone demethylase 1A	O60341	Humans	Predicted (SEA)	Prediction Confidence Score 0.214 Applicability Domain 0.253 Low confidence Statistical Significance 0.1949 Supporting Reference Compounds 85 E-value 1517.59
Click to view 3D structure	Peptide deformylase	P9WIJ3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	Predicted (SEA)	Prediction Confidence Score 0.213 Applicability Domain 0.213 Low confidence Statistical Significance 0.011 Supporting Reference Compounds 1 E-value 86.0234
Click to view 3D structure	Prolyl endopeptidase	P27028	Elizabethkingia meningoseptica	Predicted (SEA)	Prediction Confidence Score 0.213 Applicability Domain 0.213 Low confidence Statistical Significance 0.0322 Supporting Reference Compounds 1 E-value 250.363
Click to view 3D structure	Disintegrin and metalloproteinase domain-containing protein 10	O14672	Humans	Predicted (SEA)	Prediction Confidence Score 0.213 Applicability Domain 0.244 Low confidence Statistical Significance 0.0833 Supporting Reference Compounds 37 E-value 648.25
Click to view 3D structure	Angiotensin-converting enzyme	P12822	Oryctolagus cuniculus	Predicted (SEA)	Prediction Confidence Score 0.211 Applicability Domain 0.218 Low confidence Statistical Significance 0.089 Supporting Reference Compounds 26 E-value 693.247