Pyridone (CED0002885)

Record Information

Version

1.0

Creation Date

2026-04-06 09:57:17 UTC

Update Date

2026-08-27 22:48:38 UTC

SynCED ID

CED0002885

Secondary Accession Numbers

CHEM122264

Identification

Common Name

Pyridone

Class

Small Molecule

Description

Pyridone is an organic compound with the chemical formula C13H10FN3O2S and an average molecular weight of 291.30 g/mol. Pyridone belongs to the benzimidazoles, a class of organoheterocyclic compounds within the organic compounds. The compound is found in or released from 13 recorded sources across multiple sectors. Within electrical and electronic equipment, it is associated with cell phones, capacitors, batteries, printed circuit boards, wires and cables, and one additional source. In the textiles, leather and furnishings sector, it is found in synthetic textiles as well as carpets and rugs. Its presence is also recorded in food packaging within the food, food processing and cookware sector, and in medical devices within the healthcare, pharmaceuticals and veterinary products sector. Additionally, it is found in lubricants used in both the energy, oil and gas sector and the industrial manufacturing and chemical processing sector, as well as one other sector. Recorded routes of exposure for this compound include inhalation, oral ingestion, and touch.

Contaminant Type

PFAS

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₁₃H₁₀FN₃O₂S

Average Molecular Mass

Not Available

Monoisotopic Mass

291.048 g/mol

CAS Registry Number

Not Available

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

C1=CNC(=CC1=O)CSC2=NC3=CC(=C(C=C3N2)F)O

InChI Identifier

InChI=1S/C13H10FN3O2S/c14-9-4-10-11(5-12(9)19)17-13(16-10)20-6-7-3-8(18)1-2-15-7/h1-5,19H,6H2,(H,15,18)(H,16,17)

InChI Key

PXUPJAZIXWUXAX-UHFFFAOYSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
1135.0 Log mg/kg [640:2000]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Description	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000007	Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.	Agriculture & land management	Not Available
CEDs000120	Wires and cables?Wires and cables are integral components in the transmission of electrical power and signals.	Electrical & Electronic Equipment	Not Available
CEDs000121	Printed circuit boards?Printed circuit boards (PCBs) are essential components in the manufacturing of electronic devices, serving as the backbone for electrical connections and circuit pathways.	Electrical & Electronic Equipment	Not Available
CEDs000125	Batteries?Batteries are devices that store and release electrical energy through electrochemical reactions.	Electrical & Electronic Equipment	Not Available
CEDs000130	Semiconductors?Semiconductors are materials that possess electrical conductivity between that of conductors and insulators, making them essential for various electronic applications, including transistors, diodes, and integrated circuits.	Electrical & Electronic Equipment	Not Available
CEDs000138	Lubricants?Lubricants are synthetic or petroleum-derived substances used to reduce friction between surfaces in machinery and equipment, enhancing operational efficiency and longevity.	Energy, oil & gas	Not Available
CEDs000147	Food packaging?Food packaging often utilizes synthetic chemicals, such as plastics and coatings, to enhance durability, moisture resistance, and shelf life.	Food, food processing & cookware	Not Available
CEDs000174	Lubricants?Lubricants are synthetic or petroleum-based substances used to reduce friction and wear between moving parts in machinery and equipment.	Industrial manufacturing & chemical processing	Not Available
CEDs000234	Medical devices?Medical devices often incorporate synthetic chemicals in their manufacturing processes, which can contribute to contamination in healthcare settings.	Healthcare, pharmaceuticals & veterinary products	Not Available
CEDs000451	Carpets and Rugs?Carpets and rugs are commonly manufactured using synthetic fibers such as nylon, polyester, and polypropylene, which can be derived from petrochemical sources.	Textiles, leather & furnishings	Not Available
CEDs000454	Synthetic textiles?Synthetic textiles are materials derived from man-made fibers, such as polyester, nylon, and acrylic, which are produced through chemical processes involving petrochemicals.	Textiles, leather & furnishings	Not Available
CEDs000490		Personal care & cosmetics	Not Available
CEDs000492	Cell phones?Cell phones contain a variety of synthetic chemicals and materials, including plastics, metals, and glass, which can contribute to environmental contamination.	Electrical & Electronic Equipment	Not Available
CEDs000493	Capacitors?Capacitors are electronic components that store and release electrical energy, often using dielectric materials that can include synthetic chemicals.	Electrical & Electronic Equipment	Not Available

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Cytochrome P450 3A4	P08684	Humans	Predicted (SEA)	Prediction Confidence Score 0.321 Applicability Domain 0.333 Statistical Significance 0.1009 Supporting Reference Compounds 1538 E-value 785.888
Click to view 3D structure	Cytochrome P450 2C19	P33261	Humans	Predicted (SEA)	Prediction Confidence Score 0.321 Applicability Domain 0.333 Statistical Significance 0.0398 Supporting Reference Compounds 825 E-value 310.073
Click to view 3D structure	Cytochrome P450 2D6	P10635	Humans	Predicted (SEA)	Prediction Confidence Score 0.319 Applicability Domain 0.333 Statistical Significance 0.0653 Supporting Reference Compounds 1130 E-value 508.667
Click to view 3D structure	Cytochrome P450 2C8	P10632	Humans	Predicted (SEA)	Prediction Confidence Score 0.319 Applicability Domain 0.333 Statistical Significance 0.0122 Supporting Reference Compounds 305 E-value 94.9761
Click to view 3D structure	Cytochrome P450 2B6	P20813	Humans	Predicted (SEA)	Prediction Confidence Score 0.312 Applicability Domain 0.323 Statistical Significance 0.0037 Supporting Reference Compounds 150 E-value 29.1156
Click to view 3D structure	Cytochrome P450 1A2	P05177	Humans	Predicted (SEA)	Prediction Confidence Score 0.311 Applicability Domain 0.323 Statistical Significance 0.0532 Supporting Reference Compounds 793 E-value 413.924
Click to view 3D structure	Cytochrome P450 2C9	P11712	Humans	Predicted (SEA)	Prediction Confidence Score 0.306 Applicability Domain 0.333 Statistical Significance 0.1131 Supporting Reference Compounds 1245 E-value 880.63
Click to view 3D structure	D-amino-acid oxidase	P14920	Humans	Predicted (SEA)	Prediction Confidence Score 0.255 Applicability Domain 0.268 Low confidence Statistical Significance 0.0033 Supporting Reference Compounds 32 E-value 25.3788
Click to view 3D structure	D-amino-acid oxidase	O35078	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.25 Applicability Domain 0.268 Low confidence Statistical Significance 5.90e-04 Supporting Reference Compounds 9 E-value 4.5931
Click to view 3D structure	2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase	X5EH84	Staphylococcus aureus	Predicted (SEA)	Prediction Confidence Score 0.243 Applicability Domain 0.284 Low confidence Statistical Significance 5.90e-04 Supporting Reference Compounds 5 E-value 4.5931
Click to view 3D structure	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	P26281	Escherichia coli (strain K12)	Predicted (SEA)	Prediction Confidence Score 0.243 Applicability Domain 0.284 Low confidence Statistical Significance 3.90e-04 Supporting Reference Compounds 4 E-value 3.03612
Click to view 3D structure	Mitogen-activated protein kinase 14	Q16539	Humans	Predicted (SEA)	Prediction Confidence Score 0.242 Applicability Domain 0.273 Low confidence Statistical Significance 0.3792 Supporting Reference Compounds 668 E-value 2952.28
Click to view 3D structure	Tyrosine-protein kinase JAK2	O60674	Humans	Predicted (SEA)	Prediction Confidence Score 0.237 Applicability Domain 0.273 Low confidence Statistical Significance 0.5074 Supporting Reference Compounds 1022 E-value 3950.23
Click to view 3D structure	Alkaline phosphatase, germ cell type	P10696	Humans	Predicted (SEA)	Prediction Confidence Score 0.236 Applicability Domain 0.361 Statistical Significance 0.0066 Supporting Reference Compounds 31 E-value 51.3805
Click to view 3D structure	Alkaline phosphatase, tissue-nonspecific isozyme	P05186	Humans	Predicted (SEA)	Prediction Confidence Score 0.235 Applicability Domain 0.361 Statistical Significance 0.016 Supporting Reference Compounds 48 E-value 124.247
Click to view 3D structure	Collagen alpha-1(II) chain	P02458	Humans	Predicted (SEA)	Prediction Confidence Score 0.231 Applicability Domain 0.231 Low confidence Statistical Significance 0.0014 Supporting Reference Compounds 1 E-value 11.1324
Click to view 3D structure	Urokinase-type plasminogen activator	P00749	Humans	Predicted (SEA)	Prediction Confidence Score 0.228 Applicability Domain 0.254 Low confidence Statistical Significance 0.1372 Supporting Reference Compounds 151 E-value 1067.78
Click to view 3D structure	Interstitial collagenase	P03956	Humans	Predicted (SEA)	Prediction Confidence Score 0.228 Applicability Domain 0.239 Low confidence Statistical Significance 0.2332 Supporting Reference Compounds 258 E-value 1815.37
Click to view 3D structure	Matrix metalloproteinase-9	P14780	Humans	Predicted (SEA)	Prediction Confidence Score 0.228 Applicability Domain 0.239 Low confidence Statistical Significance 0.2579 Supporting Reference Compounds 292 E-value 2007.96
Click to view 3D structure	Matrix metalloproteinase-14	P50281	Humans	Predicted (SEA)	Prediction Confidence Score 0.228 Applicability Domain 0.239 Low confidence Statistical Significance 0.1842 Supporting Reference Compounds 198 E-value 1434.22
Click to view 3D structure	Collagenase 3	P45452	Humans	Predicted (SEA)	Prediction Confidence Score 0.228 Applicability Domain 0.239 Low confidence Statistical Significance 0.2468 Supporting Reference Compounds 269 E-value 1921.16
Click to view 3D structure	Voltage-gated inwardly rectifying potassium channel KCNH2	Q12809	Humans	Predicted (SEA)	Prediction Confidence Score 0.226 Applicability Domain 0.259 Low confidence Statistical Significance 0.8018 Supporting Reference Compounds 1498 E-value 6242.18
Click to view 3D structure	High affinity nerve growth factor receptor	P04629	Humans	Predicted (SEA)	Prediction Confidence Score 0.226 Applicability Domain 0.231 Low confidence Statistical Significance 0.5926 Supporting Reference Compounds 869 E-value 4613.11
Click to view 3D structure	Plasminogen	P00747	Humans	Predicted (SEA)	Prediction Confidence Score 0.225 Applicability Domain 0.254 Low confidence Statistical Significance 0.1771 Supporting Reference Compounds 195 E-value 1378.48
Click to view 3D structure	Tyrosine-protein kinase JAK3	P52333	Humans	Predicted (SEA)	Prediction Confidence Score 0.225 Applicability Domain 0.254 Low confidence Statistical Significance 0.6106 Supporting Reference Compounds 961 E-value 4753.24