Insulin Lispro (CED0004375)

Record Information
Version1.0
Creation Date2026-04-06 12:13:50 UTC
Update Date2026-04-13 20:26:53 UTC
Accession NumberCHEM124158
Identification
Common NameInsulin Lispro
ClassSmall Molecule
Description
Insulin Lispro is a compound with the chemical formula C158H234N40O42S2. It acts as an activator or agonist for two protein targets: the Insulin receptor (INSR) and the Insulin-like growth factor 1 receptor (IGF1R). This substance is found in or released from two recorded sources: antennas (Electrical & Electronic Equipment) and insulins and analogues (Healthcare, pharmaceuticals & veterinary products). Recorded routes of exposure include subcutaneous, parenteral, intravenous, and intramuscular administration.
Contaminant TypeNot Available
Chemical Structure
MOLSDFPDBSMILESInChI
SynonymsNot Available
Chemical FormulaC158H234N40O42S2
Average Molecular MassNot Available
Monoisotopic Mass3427.685 g/mol
CAS Registry Number133107-64-9
IUPAC NameNot Available
Traditional NameNot Available
SMILESNot Available
InChI IdentifierInChI=1S/C158H234N40O42S2/c1-79(2)57-104(181-131(213)86(15)173-136(218)102(50-53-125(211)212)179-152(234)127(84(11)12)194-148(230)107(60-82(7)8)184-145(227)113(67-95-70-166-78-172-95)189-150(232)115(74-199)176-123(208)73-170-134(216)116(75-241)191-140(222)105(58-80(3)4)182-144(226)112(66-94-69-165-77-171-94)188-138(220)101(48-51-119(161)204)178-146(228)114(68-120(162)205)190-153(235)126(83(9)10)193-132(214)98(160)61-89-31-21-18-22-32-89)139(221)185-110(64-92-40-44-96(202)45-41-92)142(224)183-106(59-81(5)6)147(229)195-128(85(13)14)154(236)192-117(76-242)135(217)169-71-121(206)174-100(49-52-124(209)210)137(219)177-99(38-29-55-167-158(163)164)133(215)168-72-122(207)175-108(62-90-33-23-19-24-34-90)141(223)186-109(63-91-35-25-20-26-36-91)143(225)187-111(65-93-42-46-97(203)47-43-93)149(231)196-129(87(16)200)155(237)180-103(37-27-28-54-159)156(238)198-56-30-39-118(198)151(233)197-130(88(17)201)157(239)240/h18-26,31-36,40-47,69-70,77-88,98-118,126-130,199-203,241-242H,27-30,37-39,48-68,71-76,159-160H2,1-17H3,(H2,161,204)(H2,162,205)(H,165,171)(H,166,172)(H,168,215)(H,169,217)(H,170,216)(H,173,218)(H,174,206)(H,175,207)(H,176,208)(H,177,219)(H,178,228)(H,179,234)(H,180,237)(H,181,213)(H,182,226)(H,183,224)(H,184,227)(H,185,221)(H,186,223)(H,187,225)(H,188,220)(H,189,232)(H,190,235)(H,191,222)(H,192,236)(H,193,214)(H,194,230)(H,195,229)(H,196,231)(H,197,233)(H,209,210)(H,211,212)(H,239,240)(H4,163,164,167)/t86-,87+,88+,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,126-,127-,128-,129-,130-/m0/s1
InChI KeyLNWUJZFISOIN-YQIRIWJNSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity ValuesNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
262Insulins and analoguesHealthcare, pharmaceuticals & veterinary productsNot Available
506AntennasElectrical & Electronic EquipmentNot Available
Pathways
0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureDickkopf WNT-signaling pathway inhibitor 1A6I0Z0Rattus norvegicusPredicted (SEA)50.2906
Click to view 3D structureSclerostinQ99P67Rattus norvegicusPredicted (SEA)56.5185
Neuropeptide Y receptor type 2 structureClick to view 3D structureNeuropeptide Y receptor type 2P49146HumansPredicted (SEA)91.0057
Click to view 3D structureApical membrane antigen 1Q7KQK5Plasmodium falciparum (isolate 3D7)Predicted (SEA)59.6325
IgG receptor FcRn large subunit p51 structureClick to view 3D structureIgG receptor FcRn large subunit p51P55899HumansPredicted (SEA)51.614
Click to view 3D structureBTB/POZ domain-containing protein KCTD11Q693B1HumansPredicted (SEA)60.0996
Neuropeptide Y receptor type 1 structureClick to view 3D structureNeuropeptide Y receptor type 1P25929HumansPredicted (SEA)93.8083
Glucagon-like peptide 1 receptor structureClick to view 3D structureGlucagon-like peptide 1 receptorP43220HumansPredicted (SEA)88.9817
Mucin-1 structureClick to view 3D structureMucin-1P15941HumansPredicted (SEA)69.9865
Caveolin-1 structureClick to view 3D structureCaveolin-1Q03135HumansPredicted (SEA)68.9744
Click to view 3D structureAppetite-regulating hormoneQ9BDJ6Bos taurusPredicted (SEA)54.1831
Adapter molecule crk structureClick to view 3D structureAdapter molecule crkP46108HumansPredicted (SEA)66.094
Rhombotin-2 structureClick to view 3D structureRhombotin-2P25791HumansPredicted (SEA)57.297
Appetite-regulating hormone structureClick to view 3D structureAppetite-regulating hormoneQ9UBU3HumansPredicted (SEA)58.1534
Click to view 3D structureAlpha-cobratoxinP01391Naja kaouthiaPredicted (SEA)83.9993
Click to view 3D structureG-protein coupled receptor MthO97148Drosophila melanogasterPredicted (SEA)87.9696
Mannan-binding lectin serine protease 1 structureClick to view 3D structureMannan-binding lectin serine protease 1P48740HumansPredicted (SEA)64.3035
Glucagon receptor structureClick to view 3D structureGlucagon receptorP47871HumansPredicted (SEA)95.521
Click to view 3D structureGlucagon-like peptide 1 receptorO35659Mus musculusPredicted (SEA)84.7
Click to view 3D structureKappa-type opioid receptorP41144Cavia porcellusPredicted (SEA)223.505
Delta-type opioid receptor structureClick to view 3D structureDelta-type opioid receptorP41143HumansPredicted (SEA)318.014
Kappa-type opioid receptor structureClick to view 3D structureKappa-type opioid receptorP41145HumansPredicted (SEA)316.846
Click to view 3D structureMu-type opioid receptorP97266Cavia porcellusPredicted (SEA)248.962
Click to view 3D structureGlucagon receptorP30082Rattus norvegicusPredicted (SEA)89.7602
Melanocortin receptor 4 structureClick to view 3D structureMelanocortin receptor 4P32245HumansPredicted (SEA)172.981
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available