Oteseconazole (CED0011436)

Record Information
Version1.0
Creation Date2026-04-14 19:16:24 UTC
Update Date2026-08-21 23:30:31 UTC
Accession NumberCHEM131811
Identification
Common NameOteseconazole
ClassSmall Molecule
Description
Oteseconazole is an organic compound with the formula C23H16F7N5O2. Oteseconazole belongs to the phenylpyridines, a subclass of pyridines and derivatives within the organic compounds. With an average molecular weight of 527.40 g/mol, Oteseconazole is a heavy molecule. This compound is used as an antimycotic within healthcare, pharmaceuticals, and veterinary products, and it is administered via the oral exposure route. Mechanistically, Oteseconazole acts as an inhibitor of the protein target Lanosterol 14-alpha demethylase (ERG11).
Contaminant TypeNot Available
Chemical Structure
MOLSDFPDBSMILESInChI
SynonymsNot Available
Chemical FormulaC23H16F7N5O2
Average Molecular Mass527.403 g/mol
Monoisotopic Mass527.119 g/mol
CAS Registry Number1340593-59-0
IUPAC NameNot Available
Traditional NameNot Available
SMILESO[C@@](CN1C=NN=N1)(C1=CC=C(F)C=C1F)C(F)(F)C1=CC=C(C=N1)C1=CC=C(OCC(F)(F)F)C=C1
InChI IdentifierInChI=1S/C23H16F7N5O2/c24-16-4-7-18(19(25)9-16)21(36,11-35-13-32-33-34-35)23(29,30)20-8-3-15(10-31-20)14-1-5-17(6-2-14)37-12-22(26,27)28/h1-10,13,36H,11-12H2/t21-/m0/s1
InChI KeyIDUYJRXRDSPPRC-NRFANRHFSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004i-0000090000-dc3a3639530ece938df6Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004i-0100290000-5002d68c4da5857de647Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-004i-9121000000-28a760f500f9164d2528Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-01t9-0000690000-52705cb416e370f68772Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-01ot-1300920000-7ad915bf52147eebf6e1Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-056r-4542930000-f0e837d7eed063a7cd2eNot AvailableView Spectrum
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity Values
Toxicity ValueUnitValue RangeOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalReference
3774.0Log mg/kg[2100:6700]RatLD50oralpredictedNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
348AntimycoticsHealthcare, pharmaceuticals & veterinary productsNot Available
Pathways
2 pathways
Oteseconazole Action Pathway
Oteseconazole Action Pathway
Oteseconazole Drug Metabolism Action Pathway
Oteseconazole Drug Metabolism Action Pathway
Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureUtrophinE9Q6R7Mus musculusPredicted (SEA)120.511
Voltage-gated inwardly rectifying potassium channel KCNH2 structureClick to view 3D structureVoltage-gated inwardly rectifying potassium channel KCNH2Q12809HumansPredicted (SEA)5166.62
5-hydroxytryptamine receptor 2A structureClick to view 3D structure5-hydroxytryptamine receptor 2AP28223HumansPredicted (SEA)3988.84
Vascular endothelial growth factor receptor 2 structureClick to view 3D structureVascular endothelial growth factor receptor 2P35968HumansPredicted (SEA)5126.45
Glucocorticoid receptor structureClick to view 3D structureGlucocorticoid receptorP04150HumansPredicted (SEA)443.351
Click to view 3D structureSterol 14-alpha demethylaseQ7Z1V1Trypanosoma cruzi (strain CL Brener)Predicted (SEA)103.617
Androgen receptor structureClick to view 3D structureAndrogen receptorP10275HumansPredicted (SEA)744.316
Tyrosine-protein kinase ABL1 structureClick to view 3D structureTyrosine-protein kinase ABL1P00519HumansPredicted (SEA)4611.17
Click to view 3D structureLanosterol 14-alpha demethylaseP10613YeastPredicted (SEA)15.9591
Cytochrome P450 1A2 structureClick to view 3D structureCytochrome P450 1A2P05177HumansPredicted (SEA)5164.44
Tyrosine-protein kinase Lck structureClick to view 3D structureTyrosine-protein kinase LckP06239HumansPredicted (SEA)5351.59
Rho-associated protein kinase 1 structureClick to view 3D structureRho-associated protein kinase 1Q13464HumansPredicted (SEA)4791.15
Proto-oncogene tyrosine-protein kinase receptor Ret structureClick to view 3D structureProto-oncogene tyrosine-protein kinase receptor RetP07949HumansPredicted (SEA)4697.03
Aurora kinase B structureClick to view 3D structureAurora kinase BQ96GD4HumansPredicted (SEA)5121.78
Cyclin-dependent kinase 7 structureClick to view 3D structureCyclin-dependent kinase 7P50613HumansPredicted (SEA)3820.84
Progesterone receptor structureClick to view 3D structureProgesterone receptorP06401HumansPredicted (SEA)796.32
MAP kinase-interacting serine/threonine-protein kinase 2 structureClick to view 3D structureMAP kinase-interacting serine/threonine-protein kinase 2Q9HBH9HumansPredicted (SEA)4251.19
5-hydroxytryptamine receptor 2B structureClick to view 3D structure5-hydroxytryptamine receptor 2BP41595HumansPredicted (SEA)4349.75
Mitogen-activated protein kinase 8 structureClick to view 3D structureMitogen-activated protein kinase 8P45983HumansPredicted (SEA)4969.82
Receptor-type tyrosine-protein kinase FLT3 structureClick to view 3D structureReceptor-type tyrosine-protein kinase FLT3P36888HumansPredicted (SEA)5473.11
Click to view 3D structureLanosterol 14-alpha demethylaseB8NUK6AspergillusPredicted (SEA)0.155698
Click to view 3D structureLanosterol 14-alpha demethylaseG4WW85AspergillusPredicted (SEA)0.155698
Click to view 3D structureLanosterol 14-alpha demethylaseQ9P8R0AspergillusPredicted (SEA)0.155698
Cytochrome P450 2C9 structureClick to view 3D structureCytochrome P450 2C9P11712HumansPredicted (SEA)2159.62
Cytochrome P450 3A4 structureClick to view 3D structureCytochrome P450 3A4P08684HumansPredicted (SEA)2640.49
Cytochrome P450 2C19 structureClick to view 3D structureCytochrome P450 2C19P33261HumansPredicted (SEA)1985.23
Click to view 3D structureCXC chemokine receptor 3B8PY99Macaca mulattaPredicted (SEA)10.1204
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available