JNJ-38877618 (CED0044359)

Record Information

Version

1.0

Creation Date

2026-04-14 21:05:49 UTC

Update Date

2026-08-20 04:28:09 UTC

Accession Number

CHEM134238

Identification

Common Name

JNJ-38877618

Class

Small Molecule

Description

JNJ-38877618 is an organic compound with the chemical formula C20H12F2N6 and an average molecular weight of 374.36 g/mol. JNJ-38877618 belongs to the quinolines and derivatives, a class of organoheterocyclic compounds within the organic compounds. The compound is found in or released from seven recorded sources. These sources include building and construction materials, specifically tents or canopies. Additionally, it is associated with electrical and electronic equipment, including antennas, amplifiers, microphones, electric hearing aids, and line transmission systems, among one other source.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₂₀H₁₂F₂N₆

Average Molecular Mass

374.355 g/mol

Monoisotopic Mass

374.109 g/mol

CAS Registry Number

943540-74-7

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

FC(F)(C1=NN=C2C=CC(=NN12)C1=CC=NC=C1)C1=CC2=C(C=C1)N=CC=C2

InChI Identifier

InChI=1S/C20H12F2N6/c21-20(22,15-3-4-16-14(12-15)2-1-9-24-16)19-26-25-18-6-5-17(27-28(18)19)13-7-10-23-11-8-13/h1-12H

InChI Key

KOAWAWHSMVKCON-UHFFFAOYSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Toxicity Values

Toxicity Value	Unit	Value Range	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Reference
832.0	Log mg/kg	[470:1500]	Rat	LD50	oral	predicted	Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
503	Tents Or Canopies	Building & Construction	Not Available
505	Amplifiers	Electrical & Electronic Equipment	Not Available
506	Antennas	Electrical & Electronic Equipment	Not Available
516	Electric Hearing Aids	Electrical & Electronic Equipment	Not Available
525	Line Transmission Systems	Electrical & Electronic Equipment	Not Available
528	Microphones	Electrical & Electronic Equipment	Not Available
540	X Ray Tubes	Electrical & Electronic Equipment	Not Available
620	Card Games	Recreation & sports surfaces	Not Available

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Hepatocyte growth factor receptor	P08581	Humans	Predicted (SEA)	74.891
Click to view 3D structure	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Q8TBX8	Humans	Predicted (SEA)	40.793
Click to view 3D structure	Ribosyldihydronicotinamide dehydrogenase [quinone]	P16083	Humans	Predicted (SEA)	7.31783
Click to view 3D structure	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Q13627	Humans	Predicted (SEA)	331.716
Click to view 3D structure	Dual specificity protein kinase CLK2	P49760	Humans	Predicted (SEA)	366.67
Click to view 3D structure	Receptor-type tyrosine-protein kinase FLT3	P36888	Humans	Predicted (SEA)	704.769
Click to view 3D structure	Epidermal growth factor receptor	P00533	Humans	Predicted (SEA)	706.871
Click to view 3D structure	Vascular endothelial growth factor receptor 2	P35968	Humans	Predicted (SEA)	812.357
Click to view 3D structure	Casein kinase I isoform delta	P48730	Humans	Predicted (SEA)	387.611
Click to view 3D structure	Proto-oncogene tyrosine-protein kinase Src	P12931	Humans	Predicted (SEA)	660.473
Click to view 3D structure	Tyrosine-protein kinase JAK2	O60674	Humans	Predicted (SEA)	680.558
Click to view 3D structure	Serine/threonine-protein kinase pim-1	P11309	Humans	Predicted (SEA)	576.863
Click to view 3D structure	Cyclin-dependent kinase 2	P24941	Humans	Predicted (SEA)	612.206
Click to view 3D structure	Serine/threonine-protein kinase PLK1	P53350	Humans	Predicted (SEA)	442.028
Click to view 3D structure	Mitogen-activated protein kinase 1	P28482	Humans	Predicted (SEA)	486.091
Click to view 3D structure	Interleukin-1 receptor-associated kinase 4	Q9NWZ3	Humans	Predicted (SEA)	470.054
Click to view 3D structure	Serine/threonine-protein kinase PAK 4	O96013	Humans	Predicted (SEA)	471.299
Click to view 3D structure	cAMP-dependent protein kinase catalytic subunit alpha	P17612	Humans	Predicted (SEA)	471.455
Click to view 3D structure	Ribosomal protein S6 kinase alpha-3	P51812	Humans	Predicted (SEA)	471.299
Click to view 3D structure	Glycogen synthase kinase-3 alpha	P49840	Humans	Predicted (SEA)	505.709
Click to view 3D structure	Rho-associated protein kinase 2	O75116	Humans	Predicted (SEA)	540.819
Click to view 3D structure	Serine/threonine-protein kinase Chk1	O14757	Humans	Predicted (SEA)	503.295
Click to view 3D structure	Rho-associated protein kinase 1	Q13464	Humans	Predicted (SEA)	527.74
Click to view 3D structure	Protein kinase C delta type	Q05655	Humans	Predicted (SEA)	410.188
Click to view 3D structure	RAC-alpha serine/threonine-protein kinase	P31749	Humans	Predicted (SEA)	497.768