Mivorilaner (CED0047352)

Record Information

Version

1.0

Creation Date

2026-04-15 18:08:51 UTC

Update Date

2026-05-14 20:46:59 UTC

SynCED ID

CED0047352

Secondary Accession Numbers

CHEM137543

Identification

Common Name

Mivorilaner

Class

Small Molecule

Description

Mivorilaner belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. It has the chemical formula C22H17Cl2F6N3O3S. With an average molecular weight of 588.35 g/mol, Mivorilaner is a heavy molecule.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₂₂H₁₇Cl₂F₆N₃O₃S

Average Molecular Mass

588.350 g/mol

Monoisotopic Mass

587.027 g/mol

CAS Registry Number

1414642-93-5

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

FC(F)CNC(=O)CNC(=O)C1=C2CCCC2=C(S1)C1=NO[C@@](C1)(C1=CC(Cl)=C(F)C(Cl)=C1)C(F)(F)F

InChI Identifier

InChI=1S/C22H17Cl2F6N3O3S/c23-12-4-9(5-13(24)17(12)27)21(22(28,29)30)6-14(33-36-21)18-10-2-1-3-11(10)19(37-18)20(35)32-8-16(34)31-7-15(25)26/h4-5,15H,1-3,6-8H2,(H,31,34)(H,32,35)/t21-/m1/s1

InChI Key

OFGKIOOXISVXEC-NRFANRHFSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
1431.0 Log mg/kg [800:2500]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000010	Insecticides?Insecticides are synthetic chemicals designed to control or eliminate insect pests that threaten crops and other agricultural products.	Agriculture & land management	Not Available
CEDs000596	Acaricides?Acaricides are synthetic chemicals specifically designed to target and control mite populations that can damage crops and plants.	Agriculture & land management	Not Available
CEDs000600	Herbicides And Algicides?Herbicides and algicides are synthetic chemicals primarily used to control unwanted plants and algae in various environments.	Agriculture & land management	Not Available
CEDs000602	Molluscicides?Molluscicides are synthetic chemicals specifically designed to control and eliminate mollusks, such as snails and slugs, which can be detrimental to crops and agricultural productivity.	Agriculture & land management	Not Available
CEDs000603	Nematocides?Nematocides are synthetic chemicals specifically designed to control nematodes, which are microscopic roundworms that can cause significant damage to crops and plants.	Agriculture & land management	Not Available
CEDs000604	Pest Attractants?Pest attractants are synthetic chemicals designed to lure specific pests for monitoring or control purposes.	Agriculture & land management	Not Available
CEDs000605	Pest Repellants?Pest repellents, often formulated from synthetic chemicals, are widely used to protect crops from insect infestations and other pests.	Agriculture & land management	Not Available
CEDs000606	Plant Growth Regulators?Plant Growth Regulators (PGRs) are synthetic chemicals designed to influence the growth and development of plants.	Agriculture & land management	Not Available
CEDs000607	Rodenticides(1)?Rodenticides are synthetic chemicals specifically formulated to control rodent populations, serving as a crucial tool in managing pests that can damage crops and spread diseases.	Agriculture & land management	Not Available
CEDs000608	Rodenticides?Rodenticides are chemical substances specifically designed to control rodent populations by causing death through various mechanisms, including anticoagulation or neurotoxicity.	Agriculture & land management	Not Available
CEDs000744	Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.	Wastewater, sanitation & biosolids	Not Available

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Nuclear receptor ROR-gamma	P51449	Humans	Predicted (SEA)	Prediction Confidence Score 0.214 Applicability Domain 0.231 Low confidence Statistical Significance 0.1491 Supporting Reference Compounds 102 E-value 1161.04
Click to view 3D structure	Cytochrome P450 2D6	P10635	Humans	Predicted (SEA)	Prediction Confidence Score 0.214 Applicability Domain 0.222 Low confidence Statistical Significance 0.8432 Supporting Reference Compounds 1130 E-value 6564.4
Click to view 3D structure	Cytochrome P450 3A4	P08684	Humans	Predicted (SEA)	Prediction Confidence Score 0.21 Applicability Domain 0.222 Low confidence Statistical Significance 0.9087 Supporting Reference Compounds 1538 E-value 7074.47
Click to view 3D structure	Cytochrome P450 2C9	P11712	Humans	Predicted (SEA)	Prediction Confidence Score 0.208 Applicability Domain 0.219 Low confidence Statistical Significance 0.9032 Supporting Reference Compounds 1245 E-value 7031.65
Click to view 3D structure	Cytochrome P450 2C19	P33261	Humans	Predicted (SEA)	Prediction Confidence Score 0.208 Applicability Domain 0.222 Low confidence Statistical Significance 0.8509 Supporting Reference Compounds 825 E-value 6624.42
Click to view 3D structure	Nuclear receptor ROR-beta	Q92753	Humans	Predicted (SEA)	Prediction Confidence Score 0.208 Applicability Domain 0.231 Low confidence Statistical Significance 0.0545 Supporting Reference Compounds 37 E-value 424.2
Click to view 3D structure	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	Q8DNV6	Streptococcus pneumoniae (strain ATCC BAA-255 / R6)	Predicted (SEA)	Prediction Confidence Score 0.204 Applicability Domain 0.204 Low confidence Statistical Significance 0.0141 Supporting Reference Compounds 1 E-value 109.456
Click to view 3D structure	Cytochrome P450 1A2	P05177	Humans	Predicted (SEA)	Prediction Confidence Score 0.202 Applicability Domain 0.219 Low confidence Statistical Significance 0.8732 Supporting Reference Compounds 793 E-value 6797.56
Click to view 3D structure	Voltage-gated inwardly rectifying potassium channel KCNH2	Q12809	Humans	Predicted (SEA)	Prediction Confidence Score 0.197 Applicability Domain 0.222 Low confidence Statistical Significance 0.9515 Supporting Reference Compounds 1498 E-value 7407.2
Click to view 3D structure	Cytochrome P450 2C8	P10632	Humans	Predicted (SEA)	Prediction Confidence Score 0.195 Applicability Domain 0.219 Low confidence Statistical Significance 0.778 Supporting Reference Compounds 305 E-value 6056.75
Click to view 3D structure	Transient receptor potential cation channel subfamily V member 1	Q8NER1	Humans	Predicted (SEA)	Prediction Confidence Score 0.192 Applicability Domain 0.222 Low confidence Statistical Significance 0.4882 Supporting Reference Compounds 104 E-value 3800.29
Click to view 3D structure	C-C chemokine receptor type 2	P41597	Humans	Predicted (SEA)	Prediction Confidence Score 0.191 Applicability Domain 0.2 Low confidence Statistical Significance 0.3551 Supporting Reference Compounds 72 E-value 2764.35
Click to view 3D structure	Prostaglandin E synthase	A0SYQ0	Canis lupus familiaris	Predicted (SEA)	Prediction Confidence Score 0.191 Applicability Domain 0.193 Low confidence Statistical Significance 0.0483 Supporting Reference Compounds 2 E-value 376.323
Click to view 3D structure	Serine/threonine-protein kinase A-Raf	P10398	Humans	Predicted (SEA)	Prediction Confidence Score 0.191 Applicability Domain 0.2 Low confidence Statistical Significance 0.1969 Supporting Reference Compounds 31 E-value 1532.7
Click to view 3D structure	Cannabinoid receptor 2	P34972	Humans	Predicted (SEA)	Prediction Confidence Score 0.19 Applicability Domain 0.196 Low confidence Statistical Significance 0.6733 Supporting Reference Compounds 175 E-value 5241.98
Click to view 3D structure	Myelin-associated glycoprotein	P20917	Mus musculus	Predicted (SEA)	Prediction Confidence Score 0.188 Applicability Domain 0.188 Low confidence Statistical Significance 0.0091 Supporting Reference Compounds 1 E-value 70.6092
Click to view 3D structure	E3 ubiquitin-protein ligase SMURF2	Q9HAU4	Humans	Predicted (SEA)	Prediction Confidence Score 0.188 Applicability Domain 0.188 Low confidence Statistical Significance 0.0635 Supporting Reference Compounds 1 E-value 494.265
Click to view 3D structure	Egl nine homolog 1	Q9GZT9	Humans	Predicted (SEA)	Prediction Confidence Score 0.187 Applicability Domain 0.209 Low confidence Statistical Significance 0.2628 Supporting Reference Compounds 41 E-value 2046.19
Click to view 3D structure	Histone acetyltransferase KAT5	Q92993	Humans	Predicted (SEA)	Prediction Confidence Score 0.187 Applicability Domain 0.202 Low confidence Statistical Significance 0.0717 Supporting Reference Compounds 11 E-value 558.568
Click to view 3D structure	Prolyl endopeptidase FAP	Q12884	Humans	Predicted (SEA)	Prediction Confidence Score 0.186 Applicability Domain 0.205 Low confidence Statistical Significance 0.2207 Supporting Reference Compounds 41 E-value 1718.13
Click to view 3D structure	Vascular endothelial growth factor receptor 2	P35968	Humans	Predicted (SEA)	Prediction Confidence Score 0.186 Applicability Domain 0.206 Low confidence Statistical Significance 0.9471 Supporting Reference Compounds 1660 E-value 7373.02
Click to view 3D structure	Receptor-type tyrosine-protein kinase FLT3	P36888	Humans	Predicted (SEA)	Prediction Confidence Score 0.186 Applicability Domain 0.2 Low confidence Statistical Significance 0.9361 Supporting Reference Compounds 1274 E-value 7287.39
Click to view 3D structure	Platelet-derived growth factor receptor beta	P09619	Humans	Predicted (SEA)	Prediction Confidence Score 0.186 Applicability Domain 0.208 Low confidence Statistical Significance 0.8769 Supporting Reference Compounds 597 E-value 6826.52
Click to view 3D structure	Prostaglandin E synthase	O14684	Humans	Predicted (SEA)	Prediction Confidence Score 0.186 Applicability Domain 0.194 Low confidence Statistical Significance 0.3986 Supporting Reference Compounds 69 E-value 3103.38
Click to view 3D structure	Vascular endothelial growth factor receptor 1	P17948	Humans	Predicted (SEA)	Prediction Confidence Score 0.186 Applicability Domain 0.209 Low confidence Statistical Significance 0.9034 Supporting Reference Compounds 711 E-value 7032.59