(3-aminophenyl)-morpholin-4-ylmethanone (CED0084223)

Record Information
Version1.0
Creation Date2026-08-18 10:22:27 UTC
Update Date2026-08-18 10:22:27 UTC
SynCED IDCED0084223
Secondary Accession Numbers
  • CHEM156944
Identification
Common Name(3-aminophenyl)-morpholin-4-ylmethanone
ClassSmall Molecule
Description
(3-aminophenyl)-morpholin-4-ylmethanone belongs to the benzoic acids and derivatives, a subclass of benzene and substituted derivatives within the organic compounds. This benzenoid compound has the formula C11H14N2O2 and an average molecular weight of 206.24 g/mol.
Contaminant TypeNot Available
Chemical Structure
MOLSDFPDBSMILESInChI
SynonymsNot Available
Chemical FormulaC11H14N2O2
Average Molecular Mass206.240 g/mol
Monoisotopic Mass206.106 g/mol
CAS Registry Number104775-65-7
IUPAC NameNot Available
Traditional NameNot Available
SMILESNot Available
InChI IdentifierInChI=1S/C11H14N2O2/c12-10-3-1-2-9(8-10)11(14)13-4-6-15-7-5-13/h1-3,8H,4-7,12H2
InChI KeyRFFVEVKGZGRRCP-UHFFFAOYSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic Effects
  • dark yellow colour ?
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Toxicity Values
Toxicity ValueOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalToxicity RatingReference
912.0 Log mg/kg [510:1600]RatLD50oralpredictedNot AvailableNot Available
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionDescriptionReference
gingivitisAssociated With?Not AvailableNot AvailablePMC10519255
Exposure Sources
Source IDSourceSectorReference
CEDs000013Soil?Soil serves as a critical medium for plant growth and sustains various ecological functions; however, it can become a reservoir for synthetic chemical contamination.Agriculture & land managementPMC11097069 , PMC5456987
CEDs000740Paper?Paper production involves the processing of wood fibers and the use of various chemicals, which can lead to synthetic chemical contamination.Paper, pulp & fiber productsPMC11202065 , PMC11173998
CEDs01198HoneyFood, food processing & cookwarePMC9818512 , PMC11939724
CEDs01208FruitFood, food processing & cookwarePMC11353588 , PMC11480701
CEDs01256Rice HuskFood, food processing & cookwarePMC11567527
CEDs01410SugarcaneFood, food processing & cookwarePMC10384544
CEDs01801Food PackagingPackagingPMC10978484
CEDs01879ResinIndustrial manufacturing & chemical processingPMC5307002
CEDs01910Rubber CompositesIndustrial manufacturing & chemical processingPMC10608980
CEDs01935Mixed PlasticsIndustrial manufacturing & chemical processingPMC12884476
CEDs02077Waste PlasticsWaste management, landfill & incinerationPMC8649616
CEDs02255WaterAquatic systems & sedimentsPMC9737540 , PMC5949170
CEDs02599AerosolAir, dust & atmospheric transportPMC13382692 , PMC13382692
CEDs02739GlueBuilding & ConstructionPMC9736880
CEDs02742AsphaltBuilding & ConstructionPMC8269589 , PMC8269589
CEDs02750Asphalt BinderBuilding & ConstructionPMC10532884
CEDs02753Asphalt MixtureBuilding & ConstructionPMC8269589
CEDs02885Filter PaperPaper, pulp & fiber productsPMC5191067
CEDs02903Sheet of PaperPaper, pulp & fiber productsPMC7745201
CEDs02906Paper SubstratePaper, pulp & fiber productsPMC11926751
CEDs02908PaperboardPaper, pulp & fiber productsPMC10978484
CEDs02911Paper FibersPaper, pulp & fiber productsPMC11926751
CEDs02912Paper SurfacePaper, pulp & fiber productsPMC13000773
CEDs02917Paper SubstratesPaper, pulp & fiber productsPMC9775995
CEDs02918Office PaperPaper, pulp & fiber productsPMC12683636
CEDs02919Coated PaperPaper, pulp & fiber productsPMC11859360
CEDs02961Crude OilEnergy, oil & gasPMC10574900 , PMC10574900
CEDs02980Crude OilsEnergy, oil & gasPMC12655993
CEDs03009Waste WaterWastewater, sanitation & biosolidsPMC12179051
CEDs03203TextileTextiles, leather & furnishingsPMC11314402
CEDs03205CottonTextiles, leather & furnishingsPMC6591378 , PMC8832013
CEDs03220FabricTextiles, leather & furnishingsPMC11367539
CEDs03256ClothTextiles, leather & furnishingsPMC11367539
Pathways
0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureProcollagen-lysine,2-oxoglutarate 5-dioxygenase 1Q02809HumansPredicted (SEA)
Prediction Confidence Score
0.429
Applicability Domain
0.429
Statistical Significance
1.00e-05
Supporting Reference Compounds
1
E-value
0.0778492
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 structureClick to view 3D structureMultifunctional procollagen lysine hydroxylase and glycosyltransferase LH3O60568HumansPredicted (SEA)
Prediction Confidence Score
0.429
Applicability Domain
0.429
Statistical Significance
1.00e-05
Supporting Reference Compounds
1
E-value
0.0778492
Tyrosine-protein kinase JAK2 structureClick to view 3D structureTyrosine-protein kinase JAK2O60674HumansPredicted (SEA)
Prediction Confidence Score
0.365
Applicability Domain
0.49
Statistical Significance
0.0415
Supporting Reference Compounds
1022
E-value
322.841
MAP kinase-interacting serine/threonine-protein kinase 2 structureClick to view 3D structureMAP kinase-interacting serine/threonine-protein kinase 2Q9HBH9HumansPredicted (SEA)
Prediction Confidence Score
0.344
Applicability Domain
0.49
Statistical Significance
0.0272
Supporting Reference Compounds
550
E-value
212.139
Urokinase plasminogen activator surface receptor structureClick to view 3D structureUrokinase plasminogen activator surface receptorQ03405HumansPredicted (SEA)
Prediction Confidence Score
0.339
Applicability Domain
0.339
Statistical Significance
2.20e-04
Supporting Reference Compounds
1
E-value
1.71268
Epidermal growth factor receptor structureClick to view 3D structureEpidermal growth factor receptorP00533HumansPredicted (SEA)
Prediction Confidence Score
0.331
Applicability Domain
0.49
Statistical Significance
0.0745
Supporting Reference Compounds
1301
E-value
580.132
Leucine-rich repeat serine/threonine-protein kinase 2 structureClick to view 3D structureLeucine-rich repeat serine/threonine-protein kinase 2Q5S007HumansPredicted (SEA)
Prediction Confidence Score
0.32
Applicability Domain
0.361
Statistical Significance
0.0353
Supporting Reference Compounds
336
E-value
275.197
Receptor-type tyrosine-protein kinase FLT3 structureClick to view 3D structureReceptor-type tyrosine-protein kinase FLT3P36888HumansPredicted (SEA)
Prediction Confidence Score
0.32
Applicability Domain
0.49
Statistical Significance
0.0915
Supporting Reference Compounds
1274
E-value
712.398
Tyrosine-protein kinase Lck structureClick to view 3D structureTyrosine-protein kinase LckP06239HumansPredicted (SEA)
Prediction Confidence Score
0.318
Applicability Domain
0.49
Statistical Significance
0.09
Supporting Reference Compounds
1130
E-value
700.877
Proto-oncogene tyrosine-protein kinase Src structureClick to view 3D structureProto-oncogene tyrosine-protein kinase SrcP12931HumansPredicted (SEA)
Prediction Confidence Score
0.316
Applicability Domain
0.49
Statistical Significance
0.0872
Supporting Reference Compounds
1158
E-value
679.001
Carbonic anhydrase 9 structureClick to view 3D structureCarbonic anhydrase 9Q16790HumansPredicted (SEA)
Prediction Confidence Score
0.316
Applicability Domain
0.386
Statistical Significance
0.0249
Supporting Reference Compounds
372
E-value
193.845
Carbonic anhydrase 2 structureClick to view 3D structureCarbonic anhydrase 2P00918HumansPredicted (SEA)
Prediction Confidence Score
0.316
Applicability Domain
0.386
Statistical Significance
0.0324
Supporting Reference Compounds
472
E-value
252.154
Carbonic anhydrase 12 structureClick to view 3D structureCarbonic anhydrase 12O43570HumansPredicted (SEA)
Prediction Confidence Score
0.315
Applicability Domain
0.386
Statistical Significance
0.0229
Supporting Reference Compounds
332
E-value
178.664
Dual specificity tyrosine-phosphorylation-regulated kinase 1A structureClick to view 3D structureDual specificity tyrosine-phosphorylation-regulated kinase 1AQ13627HumansPredicted (SEA)
Prediction Confidence Score
0.313
Applicability Domain
0.49
Statistical Significance
0.0744
Supporting Reference Compounds
906
E-value
579.12
Glycogen synthase kinase-3 alpha structureClick to view 3D structureGlycogen synthase kinase-3 alphaP49840HumansPredicted (SEA)
Prediction Confidence Score
0.313
Applicability Domain
0.49
Statistical Significance
0.0694
Supporting Reference Compounds
754
E-value
540.585
Cyclin-dependent kinase 2 structureClick to view 3D structureCyclin-dependent kinase 2P24941HumansPredicted (SEA)
Prediction Confidence Score
0.313
Applicability Domain
0.49
Statistical Significance
0.0842
Supporting Reference Compounds
1029
E-value
655.179
Protein mono-ADP-ribosyltransferase PARP14 structureClick to view 3D structureProtein mono-ADP-ribosyltransferase PARP14Q460N5HumansPredicted (SEA)
Prediction Confidence Score
0.312
Applicability Domain
0.396
Statistical Significance
0.0014
Supporting Reference Compounds
43
E-value
11.0546
Mitogen-activated protein kinase 8 structureClick to view 3D structureMitogen-activated protein kinase 8P45983HumansPredicted (SEA)
Prediction Confidence Score
0.309
Applicability Domain
0.49
Statistical Significance
0.0792
Supporting Reference Compounds
782
E-value
616.41
Mitogen-activated protein kinase 9 structureClick to view 3D structureMitogen-activated protein kinase 9P45984HumansPredicted (SEA)
Prediction Confidence Score
0.309
Applicability Domain
0.49
Statistical Significance
0.076
Supporting Reference Compounds
758
E-value
591.498
Serine/threonine-protein kinase D3 structureClick to view 3D structureSerine/threonine-protein kinase D3O94806HumansPredicted (SEA)
Prediction Confidence Score
0.309
Applicability Domain
0.49
Statistical Significance
0.0667
Supporting Reference Compounds
628
E-value
519.254
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform structureClick to view 3D structurePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformP42336HumansPredicted (SEA)
Prediction Confidence Score
0.309
Applicability Domain
0.344
Statistical Significance
0.0461
Supporting Reference Compounds
536
E-value
359.196
Lethal(3)malignant brain tumor-like protein 3 structureClick to view 3D structureLethal(3)malignant brain tumor-like protein 3Q96JM7HumansPredicted (SEA)
Prediction Confidence Score
0.309
Applicability Domain
0.396
Statistical Significance
9.50e-04
Supporting Reference Compounds
6
E-value
7.39568
Bromodomain-containing protein 4 structureClick to view 3D structureBromodomain-containing protein 4O60885HumansPredicted (SEA)
Prediction Confidence Score
0.308
Applicability Domain
0.397
Statistical Significance
0.0176
Supporting Reference Compounds
237
E-value
136.859
Serine/threonine-protein kinase pim-1 structureClick to view 3D structureSerine/threonine-protein kinase pim-1P11309HumansPredicted (SEA)
Prediction Confidence Score
0.307
Applicability Domain
0.49
Statistical Significance
0.0894
Supporting Reference Compounds
967
E-value
696.283
Cytochrome P450 2C9 structureClick to view 3D structureCytochrome P450 2C9P11712HumansPredicted (SEA)
Prediction Confidence Score
0.307
Applicability Domain
0.344
Statistical Significance
0.1102
Supporting Reference Compounds
1245
E-value
857.976
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available