N-(4-ethoxyphenyl)-2-hydroxypropanamide (CED0168080)

Record Information
Version1.0
Creation Date2026-08-18 11:20:41 UTC
Update Date2026-08-18 11:20:41 UTC
SynCED IDCED0168080
Secondary Accession Numbers
  • CHEM158145
Identification
Common NameN-(4-ethoxyphenyl)-2-hydroxypropanamide
ClassSmall Molecule
Description
N-(4-ethoxyphenyl)-2-hydroxypropanamide is an organic compound with the formula C11H15NO3 and an average molecular weight of 209.24 g/mol. N-(4-ethoxyphenyl)-2-hydroxypropanamide belongs to the anilides, a subclass of benzene and substituted derivatives within the organic compounds. This benzenoid substance has been found in or released from two recorded sources: ceilings in building and construction, and the preparation of vinegar in food, food processing and cookware.
Contaminant TypeNot Available
Chemical Structure
MOLSDFPDBSMILESInChI
SynonymsNot Available
Chemical FormulaC11H15NO3
Average Molecular Mass209.240 g/mol
Monoisotopic Mass209.105 g/mol
CAS Registry NumberNot Available
IUPAC NameNot Available
Traditional NameNot Available
SMILESNot Available
InChI IdentifierInChI=1S/C11H15NO3/c1-3-15-10-6-4-9(5-7-10)12-11(14)8(2)13/h4-8,13H,3H2,1-2H3,(H,12,14)
InChI KeyGHZNWXGYWUBLLI-UHFFFAOYSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Toxicity Values
Toxicity ValueOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalToxicity RatingReference
2088.0 Log mg/kg [1200:3700]RatLD50oralpredictedNot AvailableNot Available
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionDescriptionReference
Exposure Sources
Source IDSourceSectorReference
CEDs000495Ceilings?Ceilings in built environments can be a source of synthetic chemical contamination due to the materials used in their construction and finishes.Building & ConstructionPubChem
CEDs000545Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.Food, food processing & cookwarePubChem
CEDs000548Preparation Of Vinegar?Vinegar is produced through the fermentation of ethanol by acetic acid bacteria, resulting in a solution that typically contains 4-8% acetic acid.Food, food processing & cookwarePubChem
CEDs000610Aftersun Products?Aftersun products are designed to soothe and hydrate the skin after sun exposure, often containing various synthetic chemicals such as emollients, preservatives, and fragrances.Personal care & cosmeticsPubChem
CEDs000632Apparel?Apparel production often involves the use of various synthetic chemicals, including dyes, finishing agents, and preservatives.Textiles, leather & furnishingsPubChem
CEDs000640Embroidering And Tufting?Embroidering and tufting processes often involve the use of synthetic chemicals such as dyes, adhesives, and finishing agents.Textiles, leather & furnishingsPubChem
CEDs000642Footwear?Footwear production often involves the use of various synthetic chemicals, such as adhesives, dyes, and treatments, which can contribute to environmental contamination.Textiles, leather & furnishingsPubChem
CEDs000647Multicolour Dyeing?Multicolour dyeing involves the application of multiple synthetic dyes to textiles and other materials to achieve vibrant, diverse color patterns.Textiles, leather & furnishingsPubChem
CEDs000650Purses Luggage Hand Bags?Purses, luggage, and handbags are often manufactured using synthetic materials such as polyvinyl chloride (PVC), polyurethane, and various types of nylon.Textiles, leather & furnishingsPubChem
CEDs000651Purses Money Bags Wallets?Purses, money bags, and wallets are often manufactured using synthetic materials, including plastics, polyurethanes, and various treated fabrics.Textiles, leather & furnishingsPubChem
CEDs000655Slide Fasteners?Slide fasteners, commonly known as zippers, are mechanical devices used to join two edges of fabric or other materials.Textiles, leather & furnishingsPubChem
CEDs000696Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.Industrial manufacturing & chemical processingPubChem
CEDs000740Paper?Paper production involves the processing of wood fibers and the use of various chemicals, which can lead to synthetic chemical contamination.Paper, pulp & fiber productsPubChem
Pathways
0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureHydrolase, alpha/beta hydrolase fold familyO69638Mycobacterium tuberculosisPredicted (SEA)
Prediction Confidence Score
0.429
Applicability Domain
0.429
Statistical Significance
2.00e-05
Supporting Reference Compounds
1
E-value
0.155698
Click to view 3D structureBeta-1 adrenergic receptorB0FL73Cavia porcellusPredicted (SEA)
Prediction Confidence Score
0.375
Applicability Domain
0.467
Statistical Significance
7.90e-04
Supporting Reference Compounds
37
E-value
6.15009
Click to view 3D structureBeta-2 adrenergic receptorQ8K4Z4Cavia porcellusPredicted (SEA)
Prediction Confidence Score
0.368
Applicability Domain
0.467
Statistical Significance
0.0011
Supporting Reference Compounds
48
E-value
8.87481
Major prion protein structureClick to view 3D structureMajor prion proteinP23907Ovis ariesPredicted (SEA)
Prediction Confidence Score
0.353
Applicability Domain
0.468
Statistical Significance
9.00e-05
Supporting Reference Compounds
2
E-value
0.700643
Potassium voltage-gated channel subfamily B member 1 structureClick to view 3D structurePotassium voltage-gated channel subfamily B member 1Q14721HumansPredicted (SEA)
Prediction Confidence Score
0.353
Applicability Domain
0.362
Statistical Significance
8.00e-05
Supporting Reference Compounds
4
E-value
0.622794
Interleukin-18 structureClick to view 3D structureInterleukin-18Q14116HumansPredicted (SEA)
Prediction Confidence Score
0.349
Applicability Domain
0.349
Statistical Significance
5.40e-04
Supporting Reference Compounds
1
E-value
4.20386
Click to view 3D structureBeta-1 adrenergic receptorP18090Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.333
Applicability Domain
0.467
Statistical Significance
0.0012
Supporting Reference Compounds
43
E-value
9.03051
Click to view 3D structureBeta-2 adrenergic receptorP18762Mus musculusPredicted (SEA)
Prediction Confidence Score
0.333
Applicability Domain
0.333
Statistical Significance
1.90e-04
Supporting Reference Compounds
1
E-value
1.47914
Click to view 3D structureSTE20/SPS1-related proline-alanine-rich protein kinaseO88506Rattus norvegicusPredicted (SEA)
Prediction Confidence Score
0.333
Applicability Domain
0.333
Statistical Significance
3.30e-04
Supporting Reference Compounds
1
E-value
2.56902
Sentrin-specific protease 7 structureClick to view 3D structureSentrin-specific protease 7Q9BQF6HumansPredicted (SEA)
Prediction Confidence Score
0.327
Applicability Domain
0.378
Statistical Significance
0.0045
Supporting Reference Compounds
118
E-value
34.7986
Click to view 3D structureBeta-glucuronidaseP12265Mus musculusPredicted (SEA)
Prediction Confidence Score
0.323
Applicability Domain
0.323
Statistical Significance
3.00e-05
Supporting Reference Compounds
1
E-value
0.233548
Carbonic anhydrase 2 structureClick to view 3D structureCarbonic anhydrase 2P00918HumansPredicted (SEA)
Prediction Confidence Score
0.321
Applicability Domain
0.386
Statistical Significance
0.029
Supporting Reference Compounds
472
E-value
226.152
Beta-2 adrenergic receptor structureClick to view 3D structureBeta-2 adrenergic receptorP07550HumansPredicted (SEA)
Prediction Confidence Score
0.32
Applicability Domain
0.357
Statistical Significance
0.0097
Supporting Reference Compounds
258
E-value
75.358
UDP-3-O-acyl-N-acetylglucosamine deacetylase structureClick to view 3D structureUDP-3-O-acyl-N-acetylglucosamine deacetylaseO67648Aquifex aeolicus (strain VF5)Predicted (SEA)
Prediction Confidence Score
0.318
Applicability Domain
0.318
Statistical Significance
0.0031
Supporting Reference Compounds
1
E-value
24.2111
Beta-1 adrenergic receptor structureClick to view 3D structureBeta-1 adrenergic receptorP08588HumansPredicted (SEA)
Prediction Confidence Score
0.318
Applicability Domain
0.357
Statistical Significance
0.007
Supporting Reference Compounds
180
E-value
54.8837
Carbonic anhydrase 1 structureClick to view 3D structureCarbonic anhydrase 1P00915HumansPredicted (SEA)
Prediction Confidence Score
0.314
Applicability Domain
0.386
Statistical Significance
0.0284
Supporting Reference Compounds
407
E-value
220.936
Click to view 3D structureATP-dependent molecular chaperone HSP82C4YTQ8Candida albicans (strain WO-1) (Yeast)Predicted (SEA)
Prediction Confidence Score
0.312
Applicability Domain
0.423
Statistical Significance
0.0054
Supporting Reference Compounds
205
E-value
42.35
Carbonic anhydrase 7 structureClick to view 3D structureCarbonic anhydrase 7P43166HumansPredicted (SEA)
Prediction Confidence Score
0.309
Applicability Domain
0.386
Statistical Significance
0.0171
Supporting Reference Compounds
242
E-value
133.044
Collagenase 3 structureClick to view 3D structureCollagenase 3P45452HumansPredicted (SEA)
Prediction Confidence Score
0.307
Applicability Domain
0.345
Statistical Significance
0.0239
Supporting Reference Compounds
269
E-value
185.904
Prothrombin structureClick to view 3D structureProthrombinP00734HumansPredicted (SEA)
Prediction Confidence Score
0.306
Applicability Domain
0.328
Statistical Significance
0.0377
Supporting Reference Compounds
331
E-value
293.18
Carbonic anhydrase 12 structureClick to view 3D structureCarbonic anhydrase 12O43570HumansPredicted (SEA)
Prediction Confidence Score
0.303
Applicability Domain
0.316
Statistical Significance
0.0295
Supporting Reference Compounds
332
E-value
229.889
Click to view 3D structureHeat shock factor protein 1P38532Mus musculusPredicted (SEA)
Prediction Confidence Score
0.302
Applicability Domain
0.37
Statistical Significance
0.0072
Supporting Reference Compounds
166
E-value
56.0514
Interstitial collagenase structureClick to view 3D structureInterstitial collagenaseP03956HumansPredicted (SEA)
Prediction Confidence Score
0.302
Applicability Domain
0.345
Statistical Significance
0.0291
Supporting Reference Compounds
258
E-value
226.93
Cytochrome P450 3A4 structureClick to view 3D structureCytochrome P450 3A4P08684HumansPredicted (SEA)
Prediction Confidence Score
0.301
Applicability Domain
0.321
Statistical Significance
0.1644
Supporting Reference Compounds
1538
E-value
1279.92
Cytochrome P450 2D6 structureClick to view 3D structureCytochrome P450 2D6P10635HumansPredicted (SEA)
Prediction Confidence Score
0.301
Applicability Domain
0.321
Statistical Significance
0.1043
Supporting Reference Compounds
1130
E-value
812.123
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available