4-(4-benzylphenyl)-1,3-thiazol-2-amine (CED0189994)

Record Information

Version

1.0

Creation Date

2026-08-19 14:49:27 UTC

Update Date

2026-08-19 14:49:27 UTC

SynCED ID

CED0189994

Secondary Accession Numbers

CHEM187887

Identification

Common Name

4-(4-benzylphenyl)-1,3-thiazol-2-amine

Class

Small Molecule

Description

4-(4-benzylphenyl)-1,3-thiazol-2-amine is an organic compound with the chemical formula C16H14N2S and an average molecular weight of 266.40 g/mol. 4-(4-benzylphenyl)-1,3-thiazol-2-amine belongs to the diphenylmethanes, a subclass of benzene and substituted derivatives within the organic compounds. Within the broader chemical hierarchy, it is further categorized under the superclass of benzenoids. The compound has been identified in or released from six recorded sources, all of which are associated with electrical and electronic equipment. These specific sources include amplifiers, antennas, auxiliary devices, emergency protective devices, and relays, among one additional source.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₁₆H₁₄N₂S

Average Molecular Mass

266.400 g/mol

Monoisotopic Mass

266.088 g/mol

CAS Registry Number

68729-05-5

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

Not Available

InChI Identifier

InChI=1S/C16H14N2S/c17-16-18-15(11-19-16)14-8-6-13(7-9-14)10-12-4-2-1-3-5-12/h1-9,11H,10H2,(H2,17,18)

InChI Key

XYDVHKCVOMGRSY-UHFFFAOYSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
880.0 Log mg/kg [500:1600]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Description	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000505	Amplifiers?Amplifiers, commonly used in various electronic devices to enhance signal strength, can be a source of synthetic chemical contamination due to the materials and processes involved in their production and disposal.	Electrical & Electronic Equipment	PubChem
CEDs000506	Antennas?Antennas, commonly used in communication technologies, can be a source of synthetic chemical contamination through the materials and coatings used in their construction.	Electrical & Electronic Equipment	PubChem
CEDs000507	Auxiliary Devices?Auxiliary devices, such as capacitors, transformers, and circuit breakers, are integral components in various electronic systems.	Electrical & Electronic Equipment	PubChem
CEDs000517	Electric Switches?Electric switches, integral components in numerous devices, can be a source of synthetic chemical contamination due to the materials and manufacturing processes involved in their production.	Electrical & Electronic Equipment	PubChem
CEDs000520	Emergency Protective Devices?Emergency protective devices, such as circuit breakers and surge protectors, are essential components in electrical systems designed to prevent damage from overcurrent and surges.	Electrical & Electronic Equipment	PubChem
CEDs000530	Radio Transmission Systems?Radio transmission systems utilize a variety of synthetic chemicals in their manufacturing and maintenance processes.	Electrical & Electronic Equipment	PubChem
CEDs000531	Relays?Relays are electromechanical switches used to control circuits and manage electrical loads.	Electrical & Electronic Equipment	PubChem
CEDs000537	Television Systems?Television systems can be a source of synthetic chemical contamination due to the various materials and components used in their manufacture and operation.	Electrical & Electronic Equipment	PubChem
CEDs000539	Video Games?Video games, through their production and disposal processes, can be a source of synthetic chemical contamination.	Electrical & Electronic Equipment	PubChem
CEDs000583	Anchoring Equipment?Anchoring equipment, commonly used in marine applications, can be a source of synthetic chemical contamination due to the materials and coatings utilized in their manufacturing.	Marine, shipping & aquaculture	PubChem
CEDs000592	Marine Propulsion Or Steering?Marine propulsion and steering systems often rely on various synthetic chemicals, including lubricants, fuels, and hydraulic fluids.	Marine, shipping & aquaculture	PubChem
CEDs000630	Toys?Toys, particularly those made from synthetic materials such as plastics, can be a source of chemical contamination due to the presence of various additives and compounds used in their production.	Recreation & sports surfaces	PubChem
CEDs000671	Airplanes And Helicopters?Airplanes and helicopters are significant sources of synthetic chemical contamination primarily through the use of aviation fuels, lubricants, and de-icing agents.	Aviation & Aerospace	PubChem

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Transient receptor potential cation channel subfamily V member 1	Q8NER1	Humans	Predicted (SEA)	Prediction Confidence Score 0.258 Applicability Domain 0.28 Low confidence Statistical Significance 0.0366 Supporting Reference Compounds 104 E-value 285.317
Click to view 3D structure	Serine/threonine-protein kinase pim-1	P11309	Humans	Predicted (SEA)	Prediction Confidence Score 0.257 Applicability Domain 0.268 Low confidence Statistical Significance 0.3031 Supporting Reference Compounds 967 E-value 2360.0
Click to view 3D structure	Glycogen synthase kinase-3 beta	P49841	Humans	Predicted (SEA)	Prediction Confidence Score 0.256 Applicability Domain 0.268 Low confidence Statistical Significance 0.3589 Supporting Reference Compounds 1157 E-value 2793.7
Click to view 3D structure	Fatty-acid amide hydrolase 1	P97612	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.254 Applicability Domain 0.263 Low confidence Statistical Significance 0.0433 Supporting Reference Compounds 102 E-value 337.165
Click to view 3D structure	Reverse transcriptase/RNaseH	Q72547	Human immunodeficiency virus 1	Predicted (SEA)	Prediction Confidence Score 0.251 Applicability Domain 0.333 Statistical Significance 0.0106 Supporting Reference Compounds 79 E-value 82.7537
Click to view 3D structure	Aurora kinase B	Q96GD4	Humans	Predicted (SEA)	Prediction Confidence Score 0.251 Applicability Domain 0.268 Low confidence Statistical Significance 0.3641 Supporting Reference Compounds 1017 E-value 2834.88
Click to view 3D structure	Serine racemase	Q9GZT4	Humans	Predicted (SEA)	Prediction Confidence Score 0.25 Applicability Domain 0.25 Low confidence Statistical Significance 0.0093 Supporting Reference Compounds 1 E-value 72.4776
Click to view 3D structure	Vascular endothelial growth factor receptor 2	P35968	Humans	Predicted (SEA)	Prediction Confidence Score 0.25 Applicability Domain 0.268 Low confidence Statistical Significance 0.4455 Supporting Reference Compounds 1660 E-value 3468.03
Click to view 3D structure	Mitogen-activated protein kinase kinase kinase kinase 4	O95819	Humans	Predicted (SEA)	Prediction Confidence Score 0.25 Applicability Domain 0.268 Low confidence Statistical Significance 0.322 Supporting Reference Compounds 714 E-value 2506.74
Click to view 3D structure	Cell division cycle 7-related protein kinase	O00311	Humans	Predicted (SEA)	Prediction Confidence Score 0.248 Applicability Domain 0.268 Low confidence Statistical Significance 0.2183 Supporting Reference Compounds 407 E-value 1699.76
Click to view 3D structure	cAMP-dependent protein kinase catalytic subunit alpha	P17612	Humans	Predicted (SEA)	Prediction Confidence Score 0.248 Applicability Domain 0.268 Low confidence Statistical Significance 0.3261 Supporting Reference Compounds 735 E-value 2538.74
Click to view 3D structure	Dual specificity protein kinase CLK4	Q9HAZ1	Humans	Predicted (SEA)	Prediction Confidence Score 0.248 Applicability Domain 0.268 Low confidence Statistical Significance 0.3337 Supporting Reference Compounds 742 E-value 2597.67
Click to view 3D structure	Mitogen-activated protein kinase 1	P28482	Humans	Predicted (SEA)	Prediction Confidence Score 0.247 Applicability Domain 0.259 Low confidence Statistical Significance 0.3367 Supporting Reference Compounds 763 E-value 2621.11
Click to view 3D structure	Monoglyceride lipase	Q99685	Humans	Predicted (SEA)	Prediction Confidence Score 0.246 Applicability Domain 0.259 Low confidence Statistical Significance 0.0353 Supporting Reference Compounds 76 E-value 274.808
Click to view 3D structure	Rho-associated protein kinase 2	O75116	Humans	Predicted (SEA)	Prediction Confidence Score 0.246 Applicability Domain 0.268 Low confidence Statistical Significance 0.3749 Supporting Reference Compounds 811 E-value 2918.33
Click to view 3D structure	Cyclin-dependent kinase 2	P24941	Humans	Predicted (SEA)	Prediction Confidence Score 0.246 Applicability Domain 0.268 Low confidence Statistical Significance 0.4043 Supporting Reference Compounds 1029 E-value 3147.6
Click to view 3D structure	Homeodomain-interacting protein kinase 2	Q9H2X6	Humans	Predicted (SEA)	Prediction Confidence Score 0.246 Applicability Domain 0.268 Low confidence Statistical Significance 0.275 Supporting Reference Compounds 505 E-value 2140.85
Click to view 3D structure	MAP kinase-interacting serine/threonine-protein kinase 2	Q9HBH9	Humans	Predicted (SEA)	Prediction Confidence Score 0.246 Applicability Domain 0.268 Low confidence Statistical Significance 0.3013 Supporting Reference Compounds 550 E-value 2345.52
Click to view 3D structure	Interleukin-1 receptor-associated kinase 4	Q9NWZ3	Humans	Predicted (SEA)	Prediction Confidence Score 0.246 Applicability Domain 0.268 Low confidence Statistical Significance 0.3377 Supporting Reference Compounds 682 E-value 2629.12
Click to view 3D structure	Serine/threonine-protein kinase PAK 4	O96013	Humans	Predicted (SEA)	Prediction Confidence Score 0.245 Applicability Domain 0.268 Low confidence Statistical Significance 0.3514 Supporting Reference Compounds 728 E-value 2735.39
Click to view 3D structure	Leukotriene A-4 hydrolase	P09960	Humans	Predicted (SEA)	Prediction Confidence Score 0.245 Applicability Domain 0.265 Low confidence Statistical Significance 0.0502 Supporting Reference Compounds 51 E-value 391.037
Click to view 3D structure	Trace amine-associated receptor 1	Q96RJ0	Humans	Predicted (SEA)	Prediction Confidence Score 0.245 Applicability Domain 0.286 Low confidence Statistical Significance 0.0313 Supporting Reference Compounds 63 E-value 243.435
Click to view 3D structure	High affinity nerve growth factor receptor	P04629	Humans	Predicted (SEA)	Prediction Confidence Score 0.241 Applicability Domain 0.259 Low confidence Statistical Significance 0.4385 Supporting Reference Compounds 869 E-value 3413.92
Click to view 3D structure	Macrophage colony-stimulating factor 1 receptor	P07333	Humans	Predicted (SEA)	Prediction Confidence Score 0.24 Applicability Domain 0.259 Low confidence Statistical Significance 0.4284 Supporting Reference Compounds 833 E-value 3334.91
Click to view 3D structure	Serine/threonine-protein kinase pim-3	Q86V86	Humans	Predicted (SEA)	Prediction Confidence Score 0.24 Applicability Domain 0.259 Low confidence Statistical Significance 0.3257 Supporting Reference Compounds 497 E-value 2535.78