2-chloro-4-[2-[2,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]ethynyl]pyridine (CED0186725)

Record Information

Version

1.0

Creation Date

2026-08-20 01:49:21 UTC

Update Date

2026-08-20 01:49:21 UTC

Accession Number

CHEM197609

Identification

Common Name

2-chloro-4-[2-[2,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]ethynyl]pyridine

Class

Small Molecule

Description

2-chloro-4-[2-[2,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]ethynyl]pyridine is an organic compound with the formula C19H13ClF3N3O and an average molecular weight of 391.80 g/mol. 2-chloro-4-[2-[2,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]ethynyl]pyridine belongs to the imidazoles, a subclass of azoles within the organic compounds. This substance is categorized as an organoheterocyclic compound. It has been found in or released from four recorded sources, including magnets, video games, X ray tubes, and electrical and electronic equipment such as cores yokes or armatures.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₁₉H₁₃ClF₃N₃O

Average Molecular Mass

391.800 g/mol

Monoisotopic Mass

391.070 g/mol

CAS Registry Number

Not Available

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

Not Available

InChI Identifier

InChI=1S/C19H13ClF3N3O/c1-12-17(8-3-14-9-10-24-18(20)11-14)25-13(2)26(12)15-4-6-16(7-5-15)27-19(21,22)23/h4-7,9-11H,1-2H3

InChI Key

GOHCTCOGYKAJLZ-UHFFFAOYSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Toxicity Values

Toxicity Value	Unit	Value Range	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Reference
1286.0	Log mg/kg	[720:2300]	Rat	LD50	oral	predicted	Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
513	Cores Yokes Or Armatures	Electrical & Electronic Equipment	Not Available
527	Magnets	Electrical & Electronic Equipment	Not Available
539	Video Games	Electrical & Electronic Equipment	Not Available
540	X Ray Tubes	Electrical & Electronic Equipment	Not Available
661	Umbrellas	Textiles, leather & furnishings	Not Available

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Voltage-gated inwardly rectifying potassium channel KCNH2	Q12809	Humans	Predicted (SEA)	42.7392
Click to view 3D structure	Metabotropic glutamate receptor 5	P41594	Humans	Predicted (SEA)	1.01204
Click to view 3D structure	Sigma non-opioid intracellular receptor 1	Q99720	Humans	Predicted (SEA)	146.824
Click to view 3D structure	Sigma intracellular receptor 2	Q5BJF2	Humans	Predicted (SEA)	67.651
Click to view 3D structure	Alpha-2B adrenergic receptor	P18089	Humans	Predicted (SEA)	64.7706
Click to view 3D structure	Beta-3 adrenergic receptor	P13945	Humans	Predicted (SEA)	19.1509
Click to view 3D structure	G-protein coupled receptor 35	Q9HC97	Humans	Predicted (SEA)	8.56341
Click to view 3D structure	Translocator protein	P30536	Humans	Predicted (SEA)	20.4743
Click to view 3D structure	Metabotropic glutamate receptor 5	P31424	Rattus norvegicus	Predicted (SEA)	24.7561
Click to view 3D structure	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	Q9JKB0	Rattus norvegicus	Predicted (SEA)	0.389246
Click to view 3D structure	Chloroquine resistance transporter	Q9N623	Plasmodium falciparum	Predicted (SEA)	8.09632
Click to view 3D structure	Cytochrome P450 3A4	P08684	Humans	Predicted (SEA)	3949.99
Click to view 3D structure	Phospholipase A2 group V	P51433	Rattus norvegicus	Predicted (SEA)	55.2729
Click to view 3D structure	Serine protease inhibitor A3N	Q91WP6	Mus musculus	Predicted (SEA)	32.6188
Click to view 3D structure	Histamine H1 receptor	P35367	Humans	Predicted (SEA)	1634.44
Click to view 3D structure	Cytochrome P450 2D6	P10635	Humans	Predicted (SEA)	3855.72
Click to view 3D structure	Cytochrome P450 1A2	P05177	Humans	Predicted (SEA)	3159.35
Click to view 3D structure	Sodium channel protein type 5 subunit alpha	Q14524	Humans	Predicted (SEA)	561.371
Click to view 3D structure	C-C chemokine receptor type 6	O54689	Mus musculus	Predicted (SEA)	16.1926
Click to view 3D structure	Sodium channel protein type 10 subunit alpha	Q9Y5Y9	Humans	Predicted (SEA)	255.112
Click to view 3D structure	Cytochrome P450 2C9	P11712	Humans	Predicted (SEA)	5205.31
Click to view 3D structure	Mixed lineage kinase domain-like protein	Q9D2Y4	Mus musculus	Predicted (SEA)	100.114
Click to view 3D structure	RAC-alpha serine/threonine-protein kinase	P31749	Humans	Predicted (SEA)	3584.02
Click to view 3D structure	Cytochrome P450 2C19	P33261	Humans	Predicted (SEA)	4318.45
Click to view 3D structure	Sodium-dependent noradrenaline transporter	P23975	Humans	Predicted (SEA)	2098.81