2,3-dihydro-1h-indol-6-amine (CED0209486)

Record Information

Version

1.0

Creation Date

2026-08-24 10:56:27 UTC

Update Date

2026-08-24 10:56:27 UTC

SynCED ID

CED0209486

Secondary Accession Numbers

CHEM248289

Identification

Common Name

2,3-dihydro-1h-indol-6-amine

Class

Small Molecule

Description

2,3-dihydro-1h-indol-6-amine belongs to the indolines, a subclass of indoles and derivatives within the organic compounds. This organoheterocyclic compound has the formula C8H10N2 and an average molecular weight of 134.18 g/mol.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₈H₁₀N₂

Average Molecular Mass

134.180 g/mol

Monoisotopic Mass

134.084 g/mol

CAS Registry Number

15918-79-3

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

Not Available

InChI Identifier

InChI=1S/C8H10N2/c9-7-2-1-6-3-4-10-8(6)5-7/h1-2,5,10H,3-4,9H2

InChI Key

UMXPKGQJQAQXLU-UHFFFAOYSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
226.0 Log mg/kg [130:400]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000233	Brushes?Brushes used in personal care and cosmetics can be a source of synthetic chemical contamination due to the materials and coatings used in their manufacturing.	Personal care & cosmetics	Not Available
CEDs000561	Perfumes Within Detergents And Soaps?Perfumes within detergents and soaps are synthetic fragrance compounds added to enhance the sensory experience of cleaning products.	Household cleaning & consumer products	Not Available
CEDs000563	Soap Detergents?Soap detergents are synthetic surfactants designed to enhance the cleaning efficacy of water by reducing surface tension, allowing for better interaction with dirt and grease.	Household cleaning & consumer products	Not Available
CEDs000609	Aftershave?Aftershave is a grooming product typically used to soothe and protect the skin following shaving.	Personal care & cosmetics	Not Available
CEDs000611	Anti Perspirants Or Body Deoderants?Antiperspirants and body deodorants commonly contain synthetic chemicals such as aluminum compounds, parabens, and synthetic fragrances.	Personal care & cosmetics	Not Available
CEDs000612	Body Washing Or Cleaning Implements?Body washing or cleaning implements, such as synthetic sponges, loofahs, and washcloths, can be sources of synthetic chemical contamination due to the materials used in their production.	Personal care & cosmetics	Not Available
CEDs000613	Depilatories?Depilatories are products designed to remove unwanted hair through the application of synthetic chemicals that break down the protein structure of hair, facilitating its removal.	Personal care & cosmetics	Not Available
CEDs000615	Eye Makeup Products?Eye makeup products, including mascaras, eyeliners, and eyeshadows, often contain a variety of synthetic chemicals such as pigments, preservatives, and film-forming agents.	Personal care & cosmetics	Not Available
CEDs000618	Lip Makeup Products?Lip makeup products, such as lipsticks, lip glosses, and lip liners, often contain a variety of synthetic chemicals, including pigments, preservatives, and emollients.	Personal care & cosmetics	Not Available
CEDs000685	Ceramics?Ceramics can be a source of synthetic chemical contamination through various additives and processing agents used in their production.	Building & Construction	Not Available
CEDs000696	Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.	Industrial manufacturing & chemical processing	Not Available
CEDs000740	Paper?Paper production involves the processing of wood fibers and the use of various chemicals, which can lead to synthetic chemical contamination.	Paper, pulp & fiber products	Not Available

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Dual specificity protein kinase CLK4	Q9HAZ1	Humans	Predicted (SEA)	Prediction Confidence Score 0.212 Applicability Domain 0.239 Low confidence Statistical Significance 0.6954 Supporting Reference Compounds 742 E-value 5413.56
Click to view 3D structure	Cell division cycle 7-related protein kinase	O00311	Humans	Predicted (SEA)	Prediction Confidence Score 0.212 Applicability Domain 0.25 Low confidence Statistical Significance 0.5466 Supporting Reference Compounds 407 E-value 4255.39
Click to view 3D structure	Glycogen synthase kinase-3 beta	P49841	Humans	Predicted (SEA)	Prediction Confidence Score 0.211 Applicability Domain 0.227 Low confidence Statistical Significance 0.7947 Supporting Reference Compounds 1157 E-value 6186.91
Click to view 3D structure	D(2) dopamine receptor	P61169	Rat	Predicted (SEA)	Prediction Confidence Score 0.211 Applicability Domain 0.217 Low confidence Statistical Significance 0.4778 Supporting Reference Compounds 528 E-value 3719.56
Click to view 3D structure	Phenylethanolamine N-methyltransferase	P10938	Bovine	Predicted (SEA)	Prediction Confidence Score 0.237 Applicability Domain 0.289 Low confidence Statistical Significance 5.00e-04 Supporting Reference Compounds 11 E-value 3.89246
Click to view 3D structure	5-hydroxytryptamine receptor 2A	P28223	Humans	Predicted (SEA)	Prediction Confidence Score 0.23 Applicability Domain 0.268 Low confidence Statistical Significance 0.5006 Supporting Reference Compounds 955 E-value 3897.13
Click to view 3D structure	5-hydroxytryptamine receptor 2C	Q60F97	Canis lupus familiaris	Predicted (SEA)	Prediction Confidence Score 0.228 Applicability Domain 0.268 Low confidence Statistical Significance 5.70e-04 Supporting Reference Compounds 2 E-value 4.43741
Click to view 3D structure	D(3) dopamine receptor	P35462	Humans	Predicted (SEA)	Prediction Confidence Score 0.227 Applicability Domain 0.289 Low confidence Statistical Significance 0.4842 Supporting Reference Compounds 861 E-value 3769.38
Click to view 3D structure	5-hydroxytryptamine receptor 2C	P28335	Humans	Predicted (SEA)	Prediction Confidence Score 0.225 Applicability Domain 0.268 Low confidence Statistical Significance 0.5269 Supporting Reference Compounds 823 E-value 4102.19
Click to view 3D structure	D(1A) dopamine receptor	P21728	Humans	Predicted (SEA)	Prediction Confidence Score 0.224 Applicability Domain 0.238 Low confidence Statistical Significance 0.3345 Supporting Reference Compounds 425 E-value 2604.45
Click to view 3D structure	5-hydroxytryptamine receptor 2B	P41595	Humans	Predicted (SEA)	Prediction Confidence Score 0.223 Applicability Domain 0.268 Low confidence Statistical Significance 0.5216 Supporting Reference Compounds 686 E-value 4060.93
Click to view 3D structure	Alpha-2A adrenergic receptor	P08913	Humans	Predicted (SEA)	Prediction Confidence Score 0.223 Applicability Domain 0.263 Low confidence Statistical Significance 0.3951 Supporting Reference Compounds 487 E-value 3075.51
Click to view 3D structure	D(2) dopamine receptor	P14416	Humans	Predicted (SEA)	Prediction Confidence Score 0.222 Applicability Domain 0.238 Low confidence Statistical Significance 0.5905 Supporting Reference Compounds 1103 E-value 4597.39
Click to view 3D structure	Sodium-dependent serotonin transporter	P31645	Humans	Predicted (SEA)	Prediction Confidence Score 0.222 Applicability Domain 0.268 Low confidence Statistical Significance 0.465 Supporting Reference Compounds 593 E-value 3619.83
Click to view 3D structure	Protein-tyrosine kinase 2-beta	Q14289	Humans	Predicted (SEA)	Prediction Confidence Score 0.221 Applicability Domain 0.256 Low confidence Statistical Significance 0.4718 Supporting Reference Compounds 414 E-value 3672.77
Click to view 3D structure	Alpha-2C adrenergic receptor	P18825	Humans	Predicted (SEA)	Prediction Confidence Score 0.219 Applicability Domain 0.25 Low confidence Statistical Significance 0.3417 Supporting Reference Compounds 386 E-value 2660.26
Click to view 3D structure	Phenylethanolamine N-methyltransferase	P11086	Humans	Predicted (SEA)	Prediction Confidence Score 0.218 Applicability Domain 0.289 Low confidence Statistical Significance 8.60e-04 Supporting Reference Compounds 9 E-value 6.69503
Click to view 3D structure	Aurora kinase A	O14965	Humans	Predicted (SEA)	Prediction Confidence Score 0.218 Applicability Domain 0.25 Low confidence Statistical Significance 0.6764 Supporting Reference Compounds 996 E-value 5265.64
Click to view 3D structure	D(1B) dopamine receptor	P21918	Humans	Predicted (SEA)	Prediction Confidence Score 0.218 Applicability Domain 0.238 Low confidence Statistical Significance 0.2732 Supporting Reference Compounds 209 E-value 2126.92
Click to view 3D structure	Ribosomal protein S6 kinase alpha-3	P51812	Humans	Predicted (SEA)	Prediction Confidence Score 0.218 Applicability Domain 0.25 Low confidence Statistical Significance 0.6387 Supporting Reference Compounds 733 E-value 4972.62
Click to view 3D structure	3-phosphoinositide-dependent protein kinase 1	O15530	Humans	Predicted (SEA)	Prediction Confidence Score 0.217 Applicability Domain 0.255 Low confidence Statistical Significance 0.6015 Supporting Reference Compounds 591 E-value 4682.32
Click to view 3D structure	Glutathione reductase	P70619	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.216 Applicability Domain 0.216 Low confidence Statistical Significance 1.40e-04 Supporting Reference Compounds 1 E-value 1.08989
Click to view 3D structure	MAP kinase-activated protein kinase 2	P49137	Humans	Predicted (SEA)	Prediction Confidence Score 0.216 Applicability Domain 0.25 Low confidence Statistical Significance 0.6413 Supporting Reference Compounds 679 E-value 4992.63
Click to view 3D structure	Dual specificity mitogen-activated protein kinase kinase 1	Q02750	Humans	Predicted (SEA)	Prediction Confidence Score 0.215 Applicability Domain 0.239 Low confidence Statistical Significance 0.5403 Supporting Reference Compounds 391 E-value 4206.12
Click to view 3D structure	Receptor-type tyrosine-protein kinase FLT3	P36888	Humans	Predicted (SEA)	Prediction Confidence Score 0.214 Applicability Domain 0.255 Low confidence Statistical Significance 0.7599 Supporting Reference Compounds 1274 E-value 5915.68