Pyrazolo[1,5-a]pyridine-2-carboxylic acid (CED0216129)

Record Information
Version1.0
Creation Date2026-08-24 23:07:11 UTC
Update Date2026-08-24 23:07:11 UTC
SynCED IDCED0216129
Secondary Accession Numbers
  • CHEM256409
Identification
Common NamePyrazolo[1,5-a]pyridine-2-carboxylic acid
ClassSmall Molecule
Description
Pyrazolo[1,5-a]pyridine-2-carboxylic acid belongs to the pyrazolopyridines, a class of organoheterocyclic compounds within the organic compounds. This compound has the chemical formula C8H6N2O2 and an average molecular weight of 162.15 g/mol.
Contaminant TypeNot Available
Chemical Structure
MOLSDFPDBSMILESInChI
SynonymsNot Available
Chemical FormulaC8H6N2O2
Average Molecular Mass162.150 g/mol
Monoisotopic Mass162.043 g/mol
CAS Registry Number63237-88-7
IUPAC NameNot Available
Traditional NameNot Available
SMILESNot Available
InChI IdentifierInChI=1S/C8H6N2O2/c11-8(12)7-5-6-3-1-2-4-10(6)9-7/h1-5H,(H,11,12)
InChI KeyAYGNAOBAPQNTIL-UHFFFAOYSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
SpectraNot Available
Toxicity Profile
Toxicity Values
Toxicity ValueOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalToxicity RatingReference
1144.0 Log mg/kg [640:2000]RatLD50oralpredictedNot AvailableNot Available
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionDescriptionReference
Exposure Sources
Source IDSourceSectorReference
CEDs000607Rodenticides(1)?Rodenticides are synthetic chemicals specifically formulated to control rodent populations, serving as a crucial tool in managing pests that can damage crops and spread diseases.Agriculture & land managementPubChem
CEDs000608Rodenticides?Rodenticides are chemical substances specifically designed to control rodent populations by causing death through various mechanisms, including anticoagulation or neurotoxicity.Agriculture & land managementPubChem
CEDs000685Ceramics?Ceramics can be a source of synthetic chemical contamination through various additives and processing agents used in their production.Building & ConstructionPubChem
Pathways
0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureBeta-lactamaseQ44079Aeromonas hydrophilaPredicted (SEA)
Prediction Confidence Score
0.353
Applicability Domain
0.382
Statistical Significance
1.10e-04
Supporting Reference Compounds
2
E-value
0.856341
Metallo-beta-lactamase IMP-1 structureClick to view 3D structureMetallo-beta-lactamase IMP-1P52699Serratia marcescensPredicted (SEA)
Prediction Confidence Score
0.342
Applicability Domain
0.375
Statistical Significance
9.00e-05
Supporting Reference Compounds
2
E-value
0.700643
D(3) dopamine receptor structureClick to view 3D structureD(3) dopamine receptorP35462HumansPredicted (SEA)
Prediction Confidence Score
0.341
Applicability Domain
0.383
Statistical Significance
0.0331
Supporting Reference Compounds
861
E-value
258.07
D(2) dopamine receptor structureClick to view 3D structureD(2) dopamine receptorP14416HumansPredicted (SEA)
Prediction Confidence Score
0.341
Applicability Domain
0.383
Statistical Significance
0.0439
Supporting Reference Compounds
1103
E-value
341.836
Dual specificity protein kinase CLK4 structureClick to view 3D structureDual specificity protein kinase CLK4Q9HAZ1HumansPredicted (SEA)
Prediction Confidence Score
0.318
Applicability Domain
0.526
Statistical Significance
0.0579
Supporting Reference Compounds
742
E-value
450.669
D(4) dopamine receptor structureClick to view 3D structureD(4) dopamine receptorP21917HumansPredicted (SEA)
Prediction Confidence Score
0.312
Applicability Domain
0.383
Statistical Significance
0.0442
Supporting Reference Compounds
524
E-value
343.782
D(1A) dopamine receptor structureClick to view 3D structureD(1A) dopamine receptorP21728HumansPredicted (SEA)
Prediction Confidence Score
0.307
Applicability Domain
0.383
Statistical Significance
0.0315
Supporting Reference Compounds
425
E-value
244.914
Nicotinate phosphoribosyltransferase structureClick to view 3D structureNicotinate phosphoribosyltransferaseQ6XQN6HumansPredicted (SEA)
Prediction Confidence Score
0.302
Applicability Domain
0.382
Statistical Significance
5.90e-04
Supporting Reference Compounds
12
E-value
4.5931
Phosphopantetheine adenylyltransferase structureClick to view 3D structurePhosphopantetheine adenylyltransferaseP0A6I6Escherichia coli (strain K12)Predicted (SEA)
Prediction Confidence Score
0.3
Applicability Domain
0.3
Statistical Significance
2.10e-04
Supporting Reference Compounds
1
E-value
1.63483
Vascular endothelial growth factor receptor 1 structureClick to view 3D structureVascular endothelial growth factor receptor 1P17948HumansPredicted (SEA)
Prediction Confidence Score
0.29
Applicability Domain
0.526
Statistical Significance
0.114
Supporting Reference Compounds
711
E-value
887.637
Click to view 3D structureProstaglandin E2 receptor EP1 subtypeP34995HumansPredicted (SEA)
Prediction Confidence Score
0.287
Applicability Domain
0.298 Low confidence
Statistical Significance
0.0062
Supporting Reference Compounds
78
E-value
48.1108
5-hydroxytryptamine receptor 2A structureClick to view 3D structure5-hydroxytryptamine receptor 2AP28223HumansPredicted (SEA)
Prediction Confidence Score
0.284
Applicability Domain
0.383
Statistical Significance
0.1186
Supporting Reference Compounds
955
E-value
923.525
Lysine-specific demethylase 4E structureClick to view 3D structureLysine-specific demethylase 4EB2RXH2HumansPredicted (SEA)
Prediction Confidence Score
0.282
Applicability Domain
0.324
Statistical Significance
0.0034
Supporting Reference Compounds
39
E-value
26.7801
Replication protein A 70 kDa DNA-binding subunit structureClick to view 3D structureReplication protein A 70 kDa DNA-binding subunitP27694HumansPredicted (SEA)
Prediction Confidence Score
0.281
Applicability Domain
0.436
Statistical Significance
2.80e-04
Supporting Reference Compounds
3
E-value
2.17978
Metallo-beta-lactamase type 2 structureClick to view 3D structureMetallo-beta-lactamase type 2C7C422Klebsiella pneumoniaePredicted (SEA)
Prediction Confidence Score
0.28
Applicability Domain
0.375
Statistical Significance
8.00e-04
Supporting Reference Compounds
26
E-value
6.22794
RNA demethylase ALKBH5 structureClick to view 3D structureRNA demethylase ALKBH5Q6P6C2HumansPredicted (SEA)
Prediction Confidence Score
0.279
Applicability Domain
0.39
Statistical Significance
1.80e-04
Supporting Reference Compounds
9
E-value
1.40129
Serine/threonine-protein kinase pim-2 structureClick to view 3D structureSerine/threonine-protein kinase pim-2Q9P1W9HumansPredicted (SEA)
Prediction Confidence Score
0.279
Applicability Domain
0.526
Statistical Significance
0.1147
Supporting Reference Compounds
525
E-value
893.242
D(1B) dopamine receptor structureClick to view 3D structureD(1B) dopamine receptorP21918HumansPredicted (SEA)
Prediction Confidence Score
0.276
Applicability Domain
0.383
Statistical Significance
0.0393
Supporting Reference Compounds
209
E-value
305.714
Lysine-specific demethylase 4A structureClick to view 3D structureLysine-specific demethylase 4AO75164HumansPredicted (SEA)
Prediction Confidence Score
0.274
Applicability Domain
0.324
Statistical Significance
0.0037
Supporting Reference Compounds
54
E-value
28.8042
Carbonic anhydrase 1 structureClick to view 3D structureCarbonic anhydrase 1P00915HumansPredicted (SEA)
Prediction Confidence Score
0.274
Applicability Domain
0.286 Low confidence
Statistical Significance
0.0732
Supporting Reference Compounds
407
E-value
569.545
Cytochrome P450 2C9 structureClick to view 3D structureCytochrome P450 2C9P11712HumansPredicted (SEA)
Prediction Confidence Score
0.273
Applicability Domain
0.288 Low confidence
Statistical Significance
0.2841
Supporting Reference Compounds
1245
E-value
2211.54
Prostaglandin E2 receptor EP2 subtype structureClick to view 3D structureProstaglandin E2 receptor EP2 subtypeP43116HumansPredicted (SEA)
Prediction Confidence Score
0.272
Applicability Domain
0.298 Low confidence
Statistical Significance
0.0091
Supporting Reference Compounds
95
E-value
71.1542
Cytochrome P450 3A4 structureClick to view 3D structureCytochrome P450 3A4P08684HumansPredicted (SEA)
Prediction Confidence Score
0.272
Applicability Domain
0.288 Low confidence
Statistical Significance
0.3427
Supporting Reference Compounds
1538
E-value
2667.89
Cytochrome P450 1A2 structureClick to view 3D structureCytochrome P450 1A2P05177HumansPredicted (SEA)
Prediction Confidence Score
0.271
Applicability Domain
0.288 Low confidence
Statistical Significance
0.1792
Supporting Reference Compounds
793
E-value
1395.14
Lysine-specific demethylase 4C structureClick to view 3D structureLysine-specific demethylase 4CQ9H3R0HumansPredicted (SEA)
Prediction Confidence Score
0.27
Applicability Domain
0.324
Statistical Significance
0.0094
Supporting Reference Compounds
72
E-value
73.5675
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available