4-[[4-(dimethylamino)phenyl]-phenylmethoxymethyl]-n,n-dimethylaniline (CED0290116)

Record Information

Version

1.0

Creation Date

2026-08-30 23:04:11 UTC

Update Date

2026-08-30 23:04:11 UTC

SynCED ID

CED0290116

Secondary Accession Numbers

CHEM335591

Identification

Common Name

4-[[4-(dimethylamino)phenyl]-phenylmethoxymethyl]-n,n-dimethylaniline

Class

Small Molecule

Description

4-[[4-(dimethylamino)phenyl]-phenylmethoxymethyl]-n,n-dimethylaniline is a chemical compound with the formula C24H28N2O. It has an average molecular weight of 360.50 g/mol.

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Chemical Formula

C₂₄H₂₈N₂O

Average Molecular Mass

Not Available

Monoisotopic Mass

360.220 g/mol

CAS Registry Number

53370-57-3

IUPAC Name

Not Available

Traditional Name

Not Available

SMILES

CN(C)C1=CC=C(C=C1)C(C2=CC=C(C=C2)N(C)C)OCC3=CC=CC=C3

InChI Identifier

InChI=1S/C24H28N2O/c1-25(2)22-14-10-20(11-15-22)24(27-18-19-8-6-5-7-9-19)21-12-16-23(17-13-21)26(3)4/h5-17,24H,18H2,1-4H3

InChI Key

YBOBZZSJMAWFBX-UHFFFAOYSA-N

Chemical Taxonomy

Classification

Not classified

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Not Available

Spectra

Not Available

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
814.0 Log mg/kg [460:1400]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Not Available

Carcinogenicity (IARC Classification)

Not Available

Minimum Risk Level

Not Available

Symptoms

Not Available

Treatment

Not Available

Health Effects

Health Effect	Relationship	Direction	Reference

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000519	Electrodes?Electrodes, used in various electrical and electronic applications, can be a source of synthetic chemical contamination due to the materials from which they are constructed and the processes involved in their manufacturing.	Electrical & Electronic Equipment	Not Available
CEDs000615	Eye Makeup Products?Eye makeup products, including mascaras, eyeliners, and eyeshadows, often contain a variety of synthetic chemicals such as pigments, preservatives, and film-forming agents.	Personal care & cosmetics	Not Available
CEDs000618	Lip Makeup Products?Lip makeup products, such as lipsticks, lip glosses, and lip liners, often contain a variety of synthetic chemicals, including pigments, preservatives, and emollients.	Personal care & cosmetics	Not Available
CEDs000739	Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.	Paper, pulp & fiber products	Not Available

Pathways

0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	Sodium-dependent noradrenaline transporter	P23975	Humans	Predicted (SEA)	Prediction Confidence Score 0.367 Applicability Domain 0.459 Statistical Significance 0.0091 Supporting Reference Compounds 451 E-value 70.6871
Click to view 3D structure	Sodium-dependent dopamine transporter	P23977	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.338 Applicability Domain 0.35 Statistical Significance 0.0091 Supporting Reference Compounds 203 E-value 71.232
Click to view 3D structure	Sodium-dependent serotonin transporter	P31652	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.338 Applicability Domain 0.35 Statistical Significance 0.0154 Supporting Reference Compounds 297 E-value 120.199
Click to view 3D structure	Sodium-dependent serotonin transporter	P31645	Humans	Predicted (SEA)	Prediction Confidence Score 0.338 Applicability Domain 0.356 Statistical Significance 0.0246 Supporting Reference Compounds 593 E-value 191.587
Click to view 3D structure	Voltage-gated inwardly rectifying potassium channel KCNH2	Q12809	Humans	Predicted (SEA)	Prediction Confidence Score 0.336 Applicability Domain 0.459 Statistical Significance 0.0816 Supporting Reference Compounds 1498 E-value 635.172
Click to view 3D structure	Sodium-dependent dopamine transporter	Q01959	Humans	Predicted (SEA)	Prediction Confidence Score 0.331 Applicability Domain 0.348 Statistical Significance 0.0199 Supporting Reference Compounds 506 E-value 154.92
Click to view 3D structure	Histamine H1 receptor	P35367	Humans	Predicted (SEA)	Prediction Confidence Score 0.322 Applicability Domain 0.459 Statistical Significance 0.0315 Supporting Reference Compounds 507 E-value 245.225
Click to view 3D structure	5-hydroxytryptamine receptor 2C	P28335	Humans	Predicted (SEA)	Prediction Confidence Score 0.322 Applicability Domain 0.459 Statistical Significance 0.0418 Supporting Reference Compounds 823 E-value 325.565
Click to view 3D structure	5-hydroxytryptamine receptor 2A	P28223	Humans	Predicted (SEA)	Prediction Confidence Score 0.322 Applicability Domain 0.459 Statistical Significance 0.0532 Supporting Reference Compounds 955 E-value 414.002
Click to view 3D structure	5-hydroxytryptamine receptor 2B	P41595	Humans	Predicted (SEA)	Prediction Confidence Score 0.322 Applicability Domain 0.459 Statistical Significance 0.0321 Supporting Reference Compounds 686 E-value 250.052
Click to view 3D structure	Muscarinic acetylcholine receptor M1	P11229	Humans	Predicted (SEA)	Prediction Confidence Score 0.321 Applicability Domain 0.459 Statistical Significance 0.0174 Supporting Reference Compounds 385 E-value 135.613
Click to view 3D structure	Muscarinic acetylcholine receptor M5	P08912	Humans	Predicted (SEA)	Prediction Confidence Score 0.321 Applicability Domain 0.459 Statistical Significance 0.01 Supporting Reference Compounds 266 E-value 77.6157
Click to view 3D structure	Muscarinic acetylcholine receptor M2	P08172	Humans	Predicted (SEA)	Prediction Confidence Score 0.321 Applicability Domain 0.459 Statistical Significance 0.0149 Supporting Reference Compounds 373 E-value 115.995
Click to view 3D structure	Muscarinic acetylcholine receptor M3	P20309	Humans	Predicted (SEA)	Prediction Confidence Score 0.321 Applicability Domain 0.459 Statistical Significance 0.0116 Supporting Reference Compounds 310 E-value 90.3829
Click to view 3D structure	Muscarinic acetylcholine receptor M4	P08173	Humans	Predicted (SEA)	Prediction Confidence Score 0.321 Applicability Domain 0.459 Statistical Significance 0.0116 Supporting Reference Compounds 297 E-value 90.4608
Click to view 3D structure	Sigma non-opioid intracellular receptor 1	Q99720	Humans	Predicted (SEA)	Prediction Confidence Score 0.319 Applicability Domain 0.35 Statistical Significance 0.0443 Supporting Reference Compounds 562 E-value 345.106
Click to view 3D structure	Excitatory amino acid transporter 4	O35921	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.296 Applicability Domain 0.357 Statistical Significance 2.50e-04 Supporting Reference Compounds 3 E-value 1.94623
Click to view 3D structure	Norepinephrine transporter	Q9WTR4	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.296 Applicability Domain 0.34 Statistical Significance 0.0116 Supporting Reference Compounds 112 E-value 90.3829
Click to view 3D structure	Sigma non-opioid intracellular receptor 1	Q9R0C9	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.295 Applicability Domain 0.34 Statistical Significance 0.025 Supporting Reference Compounds 207 E-value 194.545
Click to view 3D structure	Sigma non-opioid intracellular receptor 1	Q60492	Cavia porcellus	Predicted (SEA)	Prediction Confidence Score 0.291 Applicability Domain 0.34 Statistical Significance 0.0429 Supporting Reference Compounds 229 E-value 334.285
Click to view 3D structure	Transporter	Q63380	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.29 Applicability Domain 0.34 Statistical Significance 0.0054 Supporting Reference Compounds 54 E-value 42.1943
Click to view 3D structure	Alpha-2A adrenergic receptor	P08913	Humans	Predicted (SEA)	Prediction Confidence Score 0.289 Applicability Domain 0.356 Statistical Significance 0.0544 Supporting Reference Compounds 487 E-value 423.5
Click to view 3D structure	Cytochrome P450 2D6	P10635	Humans	Predicted (SEA)	Prediction Confidence Score 0.288 Applicability Domain 0.356 Statistical Significance 0.1502 Supporting Reference Compounds 1130 E-value 1169.37
Click to view 3D structure	Alpha-2B adrenergic receptor	P18089	Humans	Predicted (SEA)	Prediction Confidence Score 0.288 Applicability Domain 0.356 Statistical Significance 0.0377 Supporting Reference Compounds 340 E-value 293.414
Click to view 3D structure	Trace amine-associated receptor 1	Q96RJ0	Humans	Predicted (SEA)	Prediction Confidence Score 0.283 Applicability Domain 0.333 Statistical Significance 0.0064 Supporting Reference Compounds 63 E-value 50.1349