Tubocurarine (CED0003747)

Record Information

Version

1.0

Creation Date

2009-07-23 18:26:15 UTC

Update Date

2026-05-14 16:58:42 UTC

SynCED ID

CED0003747

Secondary Accession Numbers

CHEM002432
T3D3097

Identification

Common Name

Tubocurarine

Class

Small Molecule

Description

Tubocurarine belongs to the ethers, a subclass of organooxygen compounds within the organic compounds. With an average molecular weight of 609.73 g/mol, Tubocurarine is a heavy molecule. This exogenous compound has the chemical formula C37H41N2O6 and exists as a solid at room temperature. It functions as a muscle relaxant and a nicotinic antagonist. As a non-depolarizing muscle relaxant, it acts as a competitive antagonist at nicotinic acetylcholine receptors. The compound targets several proteins, including the acetylcholine receptor subunit alpha (CHRNA1), neuronal acetylcholine receptor subunit alpha-2 (CHRNA2), neuronal acetylcholine receptor subunit alpha-3 (CHRNA3), and neuronal acetylcholine receptor subunit alpha-4 (CHRNA4), among 12 other proteins. Other recorded protein targets include acetylcholinesterase (ACHE), 5-hydroxytryptamine receptor 3A (HTR3A), solute carrier family 22 member 2 (SLC22A2), and multidrug and toxin extrusion protein 2 (SLC47A2). In terms of health effects, Tubocurarine has a therapeutic effect on inflammation (PMC12970233). Tubocurarine is found in several recorded sources, including healthcare, pharmaceuticals, and veterinary products as a muscle relaxant, as well as in food preservation. It is also associated with household cleaning and consumer products such as cigar cigarettes, pipe accessories, other smoking requisites, tobacco smoke filters, and non-electric simulated smoking devices. Additionally, it is found in electrically stimulated smoking devices and in building and construction materials like tents or canopies. Recorded exposure routes for this compound include intravenous and intramuscular administration.

Contaminant Type

Amine
Drug
Ether
Metabolite
Muscle Relaxant, Skeletal
Natural Compound
Neuromuscular Nondepolarizing Agent
Nicotinic Antagonist
Organic Compound
Plant Toxin

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
(+)-Tubocurarine	ChEBI
7',12'-Dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraranium	ChEBI
D-Tubocurarine	ChEBI
Tubocurarin	ChEBI
D-Tubocurarine chloride	HMDB
Isoquinoline alkaloid	HMDB
Tubocurarine chloride	HMDB
Tubocurarinum	HMDB
D-Tubocurare	HMDB
Tubocurare	HMDB

Chemical Formula

C₃₇H₄₁N₂O₆

Average Molecular Mass

609.731 g/mol

Monoisotopic Mass

609.296 g/mol

CAS Registry Number

6989-98-6

IUPAC Name

(1S,16R)-9,21-dihydroxy-10,25-dimethoxy-15,15,30-trimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.2³,⁶.1⁸,¹².1¹⁸,²².0²⁷,³¹.0¹⁶,³⁴]hexatriaconta-3,5,8(34),9,11,18(33),19,21,24,26,31,35-dodecaen-15-ium

Traditional Name

tubocurarine

SMILES

[H][C@@]12CC3=CC=C(OC4=C5C(CC[N+](C)(C)[C@]5([H])CC5=CC(OC6=C(OC)C=C(CCN1C)C2=C6)=C(O)C=C5)=CC(OC)=C4O)C=C3

InChI Identifier

InChI=1S/C37H40N2O6/c1-38-14-12-24-19-32(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-37-35-25(20-34(43-5)36(37)41)13-15-39(2,3)29(35)17-23-8-11-30(40)31(18-23)45-33/h6-11,18-21,28-29H,12-17H2,1-5H3,(H-,40,41)/p+1/t28-,29+/m0/s1

InChI Key

JFJZZMVDLULRGK-URLMMPGGSA-O

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as diarylethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are aryl groups.

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Ethers

Direct Parent

Diarylethers

Alternative Parents

Substituents

Diaryl ether
Tetrahydroisoquinoline
Anisole
Alkyl aryl ether
1-hydroxy-2-unsubstituted benzenoid
Aralkylamine
Benzenoid
Tetraalkylammonium salt
Quaternary ammonium salt
Tertiary amine
Tertiary aliphatic amine
Oxacycle
Azacycle
Organoheterocyclic compound
Amine
Organic nitrogen compound
Organonitrogen compound
Hydrocarbon derivative
Organopnictogen compound
Organic salt
Organic cation
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

benzylisoquinoline alkaloid (CHEBI:9774 )
Isoquinoline alkaloids (C07547 )

Biological Properties

Status

Detected and Not Quantified

Origin

Exogenous

Cellular Locations

Cytoplasm
Membrane

Biofluid Locations

Not Available

Tissue Locations

Not Available

Applications

Biological Roles

nicotinic antagonist ?

Chemical Roles

Not Available

Organoleptic Effects

Not Available

Physical Properties

State

Solid

Appearance

White powder.

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	3.23e-04 g/L

Predicted Properties

Property	Value	Source
Water Solubility	0.00032 g/L	ALOGPS
logP	3.12	ALOGPS
logP	3.14	ChemAxon
logS	-6.3	ALOGPS
pKa (Strongest Acidic)	6.45	ChemAxon
pKa (Strongest Basic)	8.12	ChemAxon
Physiological Charge	1	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	80.62 Å²	ChemAxon
Rotatable Bond Count	2	ChemAxon
Refractivity	187.06 m³·mol⁻¹	ChemAxon
Polarizability	66.41 Å³	ChemAxon
Number of Rings	7	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	Deposition Date	View
Predicted GC-MS	Predicted GC-MS Spectrum	splash10-052f-0000091000-3781da48d16d597964cc	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	splash10-01bi-0000009000-cf3870f9fb70af6daa94	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum	Not Available	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0000090000-3b12a16109f25ee30930	Not Available	View Spectrum
LC-MS/MS	LC-MS/MS Spectrum	splash10-03di-0000090000-7ed720c5e8c5ce8facd3	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0a59-0000089000-ac5f8d663869b48af1f0	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0560-0000091000-b985ecd4a2b2ff4197d8	Not Available	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum	splash10-0fk9-0000090000-ae66666801b8fb874ed4	Not Available	View Spectrum

Toxicity Profile

Toxicity Values

Toxicity Value	Organism	Dose Descriptor	Route of Exposure	Predicted or Experimental	Toxicity Rating	Reference
17.0 Log mg/kg [9:30]	Rat	LD50	oral	predicted	Not Available	Not Available

Toxicity / Toxin Class

Not Available

Mechanism of Toxicity

Tubocurarine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesterase. Because of its essential function, chemicals that interfere with the action of acetylcholinesterase are potent neurotoxins, causing excessive salivation and eye-watering in low doses, followed by muscle spasms and ultimately death. Nerve gases and many substances used in insecticides have been shown to act by binding a serine in the active site of acetylcholine esterase, inhibiting the enzyme completely. Acetylcholine esterase breaks down the neurotransmitter acetylcholine, which is released at nerve and muscle junctions, in order to allow the muscle or organ to relax. The result of acetylcholine esterase inhibition is that acetylcholine builds up and continues to act so that any nerve impulses are continually transmitted and muscle contractions do not stop. Among the most common acetylcholinesterase inhibitors are phosphorus-based compounds, which are designed to bind to the active site of the enzyme. The structural requirements are a phosphorus atom bearing two lipophilic groups, a leaving group (such as a halide or thiocyanate), and a terminal oxygen.

Carcinogenicity (IARC Classification)

No indication of carcinogenicity to humans (not listed by IARC).

Minimum Risk Level

Not Available

Symptoms

Curare is a muscle relaxant and thus causes paraylsis. (2)

Treatment

If the compound has been ingested, rapid gastric lavage should be performed using 5% sodium bicarbonate. For skin contact, the skin should be washed with soap and water. If the compound has entered the eyes, they should be washed with large quantities of isotonic saline or water. In serious cases, atropine and/or pralidoxime should be administered. Anti-cholinergic drugs work to counteract the effects of excess acetylcholine and reactivate AChE. Atropine can be used as an antidote in conjunction with pralidoxime or other pyridinium oximes (such as trimedoxime or obidoxime), though the use of '-oximes' has been found to be of no benefit, or possibly harmful, in at least two meta-analyses. Atropine is a muscarinic antagonist, and thus blocks the action of acetylcholine peripherally.

Health Effects

Health Effect	Relationship	Direction	Reference
inflammation?	has_therapeutic_effect_on	Not Available	PMC12970233

Exposure Sources

Source ID	Source	Sector	Reference
CEDs000233	Brushes?Brushes used in personal care and cosmetics can be a source of synthetic chemical contamination due to the materials and coatings used in their manufacturing.	Personal care & cosmetics	Not Available
CEDs000365	Muscle relaxants?Muscle relaxants are synthetic chemicals primarily used to alleviate muscle spasms and discomfort by acting on the central nervous system or peripheral neuromuscular junctions.	Healthcare, pharmaceuticals & veterinary products	Not Available
CEDs000503	Tents Or Canopies?Tents and canopies used in various applications can be a source of synthetic chemical contamination primarily due to the materials from which they are made.	Building & Construction	Not Available
CEDs000518	Electrically Stimulated Smoking Devices?Electrically stimulated smoking devices, commonly known as e-cigarettes or vape pens, utilize electrical components to heat a liquid solution, often containing nicotine, flavorings, and other additives, to produce an aerosol for inhalation.	Electrical & Electronic Equipment	Not Available
CEDs000545	Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.	Food, food processing & cookware	Not Available
CEDs000556	Cigar Cigarettes?Cigar cigarettes are a source of synthetic chemical contamination due to the combustion of various tobacco blends and additives.	Household cleaning & consumer products	Not Available
CEDs000559	Non Electric Simulated Smoking Devices?Non-electric simulated smoking devices, often designed to mimic the experience of smoking without combustion, can be sources of synthetic chemical contamination due to the materials and chemicals used in their construction and operation.	Household cleaning & consumer products	Not Available
CEDs000560	Other Smoking Requisites?Other smoking requisites, including items such as lighters, matches, and rolling papers, can introduce synthetic chemical contamination through various components and additives.	Household cleaning & consumer products	Not Available
CEDs000562	Pipe Accessories?Pipe accessories, such as fittings, connectors, and seals, are components used in plumbing systems to facilitate the flow of liquids and gases.	Household cleaning & consumer products	Not Available
CEDs000569	Tobacco Smoke Filters?Tobacco smoke filters are designed to reduce the inhalation of harmful substances in cigarette smoke, including tar and other particulate matter.	Household cleaning & consumer products	Not Available
CEDs000578	Making Cigars?The process of making cigars involves several steps, including the cultivation of tobacco, fermentation, and the application of various additives to enhance flavor and preservation.	Industrial manufacturing & chemical processing	Not Available
CEDs000580	Manufacture Preparation Of Tobacco Products?The manufacture and preparation of tobacco products involve various processes that can result in the introduction of synthetic chemicals into the environment.	Industrial manufacturing & chemical processing	Not Available
CEDs000611	Anti Perspirants Or Body Deoderants?Antiperspirants and body deodorants commonly contain synthetic chemicals such as aluminum compounds, parabens, and synthetic fragrances.	Personal care & cosmetics	Not Available
CEDs000614	Essential Oils Or Perfumes?Essential oils and perfumes are complex mixtures of volatile compounds derived from natural or synthetic sources, commonly used for their aromatic properties.	Personal care & cosmetics	Not Available
CEDs000632	Apparel?Apparel production often involves the use of various synthetic chemicals, including dyes, finishing agents, and preservatives.	Textiles, leather & furnishings	Not Available
CEDs000696	Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.	Industrial manufacturing & chemical processing	Not Available
CEDs000739	Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.	Paper, pulp & fiber products	Not Available
CEDs000740	Paper?Paper production involves the processing of wood fibers and the use of various chemicals, which can lead to synthetic chemical contamination.	Paper, pulp & fiber products	Not Available

Pathways

1 pathwayPathway Source: PathBank

Tubocurarine Drug Metabolism Action Pathway

Targets

Structure	Protein	UniProt ID	Organism	Relationship	Details
Click to view 3D structure	D(1A) dopamine receptor	P21728	Humans	Predicted (SEA)	Prediction Confidence Score 0.345 Applicability Domain 0.357 Statistical Significance 0.0155 Supporting Reference Compounds 425 E-value 121.056
Click to view 3D structure	D(2) dopamine receptor	P14416	Humans	Predicted (SEA)	Prediction Confidence Score 0.343 Applicability Domain 0.357 Statistical Significance 0.0429 Supporting Reference Compounds 1103 E-value 334.362
Click to view 3D structure	5-hydroxytryptamine receptor 2A	P28223	Humans	Predicted (SEA)	Prediction Confidence Score 0.332 Applicability Domain 0.357 Statistical Significance 0.0451 Supporting Reference Compounds 955 E-value 351.256
Click to view 3D structure	5-hydroxytryptamine receptor 1A	P08908	Humans	Predicted (SEA)	Prediction Confidence Score 0.33 Applicability Domain 0.349 Statistical Significance 0.0422 Supporting Reference Compounds 953 E-value 328.835
Click to view 3D structure	D(2) dopamine receptor	P61169	Rat	Predicted (SEA)	Prediction Confidence Score 0.329 Applicability Domain 0.354 Statistical Significance 0.0336 Supporting Reference Compounds 528 E-value 261.807
Click to view 3D structure	D(1A) dopamine receptor	P18901	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.329 Applicability Domain 0.354 Statistical Significance 0.014 Supporting Reference Compounds 206 E-value 108.755
Click to view 3D structure	D(1B) dopamine receptor	P21918	Humans	Predicted (SEA)	Prediction Confidence Score 0.327 Applicability Domain 0.357 Statistical Significance 0.0136 Supporting Reference Compounds 209 E-value 106.108
Click to view 3D structure	D(3) dopamine receptor	P35462	Humans	Predicted (SEA)	Prediction Confidence Score 0.326 Applicability Domain 0.349 Statistical Significance 0.0426 Supporting Reference Compounds 861 E-value 331.949
Click to view 3D structure	5-hydroxytryptamine receptor 2C	P28335	Humans	Predicted (SEA)	Prediction Confidence Score 0.326 Applicability Domain 0.349 Statistical Significance 0.0386 Supporting Reference Compounds 823 E-value 300.498
Click to view 3D structure	5-hydroxytryptamine receptor 7	P34969	Humans	Predicted (SEA)	Prediction Confidence Score 0.326 Applicability Domain 0.349 Statistical Significance 0.0305 Supporting Reference Compounds 565 E-value 237.596
Click to view 3D structure	Tissue factor	P13726	Humans	Predicted (SEA)	Prediction Confidence Score 0.318 Applicability Domain 0.333 Statistical Significance 0.0033 Supporting Reference Compounds 29 E-value 25.4567
Click to view 3D structure	ATP-binding cassette sub-family C member 4	O15439	Humans	Predicted (SEA)	Prediction Confidence Score 0.316 Applicability Domain 1.0 Statistical Significance 6.00e-05 Supporting Reference Compounds 30 E-value 0.467095
Click to view 3D structure	5-hydroxytryptamine receptor 2B	P41595	Humans	Predicted (SEA)	Prediction Confidence Score 0.315 Applicability Domain 0.349 Statistical Significance 0.0377 Supporting Reference Compounds 686 E-value 293.414
Click to view 3D structure	D(4) dopamine receptor	P21917	Humans	Predicted (SEA)	Prediction Confidence Score 0.312 Applicability Domain 0.333 Statistical Significance 0.0438 Supporting Reference Compounds 524 E-value 340.98
Click to view 3D structure	Multidrug and toxin extrusion protein 1	Q96FL8	Humans	Predicted (SEA)	Prediction Confidence Score 0.311 Applicability Domain 1.0 Statistical Significance 1.20e-04 Supporting Reference Compounds 35 E-value 0.934191
Click to view 3D structure	Alpha-1A adrenergic receptor	P43140	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.307 Applicability Domain 0.354 Statistical Significance 0.0197 Supporting Reference Compounds 208 E-value 153.052
Click to view 3D structure	Neuronal acetylcholine receptor subunit alpha-7	Q05941	Rattus norvegicus	Predicted (SEA)	Prediction Confidence Score 0.306 Applicability Domain 0.986 Statistical Significance 0.0019 Supporting Reference Compounds 55 E-value 14.48
Click to view 3D structure	Alpha-1B adrenergic receptor	P35368	Humans	Predicted (SEA)	Prediction Confidence Score 0.302 Applicability Domain 0.349 Statistical Significance 0.0271 Supporting Reference Compounds 298 E-value 211.049
Click to view 3D structure	Alpha-2C adrenergic receptor	P18825	Humans	Predicted (SEA)	Prediction Confidence Score 0.297 Applicability Domain 0.349 Statistical Significance 0.0338 Supporting Reference Compounds 386 E-value 263.52
Click to view 3D structure	Alpha-1A adrenergic receptor	P35348	Humans	Predicted (SEA)	Prediction Confidence Score 0.29 Applicability Domain 0.322 Statistical Significance 0.0456 Supporting Reference Compounds 376 E-value 355.382
Click to view 3D structure	Alpha-1D adrenergic receptor	P25100	Humans	Predicted (SEA)	Prediction Confidence Score 0.289 Applicability Domain 0.322 Statistical Significance 0.0316 Supporting Reference Compounds 258 E-value 246.081
Click to view 3D structure	Sigma non-opioid intracellular receptor 1	Q99720	Humans	Predicted (SEA)	Prediction Confidence Score 0.285 Applicability Domain 0.296 Low confidence Statistical Significance 0.085 Supporting Reference Compounds 562 E-value 661.563
Click to view 3D structure	5-hydroxytryptamine receptor 6	P50406	Humans	Predicted (SEA)	Prediction Confidence Score 0.285 Applicability Domain 0.349 Statistical Significance 0.0633 Supporting Reference Compounds 536 E-value 492.708
Click to view 3D structure	Sodium-dependent dopamine transporter	Q01959	Humans	Predicted (SEA)	Prediction Confidence Score 0.277 Applicability Domain 0.349 Statistical Significance 0.0773 Supporting Reference Compounds 506 E-value 601.619
Click to view 3D structure	Alpha-2B adrenergic receptor	P18089	Humans	Predicted (SEA)	Prediction Confidence Score 0.272 Applicability Domain 0.322 Statistical Significance 0.0585 Supporting Reference Compounds 340 E-value 455.184
Click to view 3D structure	5-hydroxytryptamine receptor 3A	P46098	Humans	Known	Not Available
Click to view 3D structure	Acetylcholinesterase	P22303	Humans	Known	Not Available
Click to view 3D structure	Neuronal acetylcholine receptor subunit alpha-7	P36544	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Acetylcholine receptor subunit alpha	P02708	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Acetylcholine receptor subunit beta	P11230	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Acetylcholine receptor subunit delta	Q07001	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Acetylcholine receptor subunit epsilon	Q04844	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Acetylcholine receptor subunit gamma	P07510	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Multidrug and toxin extrusion protein 1	Q96FL8	Humans	Known	Not Available
Click to view 3D structure	Multidrug and toxin extrusion protein 2	Q86VL8	Humans	Known	Not Available
Click to view 3D structure	Neuronal acetylcholine receptor subunit alpha-10	Q9GZZ6	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Neuronal acetylcholine receptor subunit alpha-2	Q15822	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Neuronal acetylcholine receptor subunit alpha-3	P32297	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Neuronal acetylcholine receptor subunit alpha-4	P43681	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Neuronal acetylcholine receptor subunit alpha-5	P30532	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Neuronal acetylcholine receptor subunit alpha-6	Q15825	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Neuronal acetylcholine receptor subunit alpha-9	Q9UGM1	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Neuronal acetylcholine receptor subunit beta-2	P17787	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Neuronal acetylcholine receptor subunit beta-3	Q05901	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Neuronal acetylcholine receptor subunit beta-4	P30926	Humans	Known	Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256)
Click to view 3D structure	Solute carrier family 22 member 2	O15244	Humans	Known	Not Available

Concentrations

Not Available

External Links

DrugBank ID

DB01199

HMDB ID

HMDB0015330

FooDB ID

Not Available

Phenol Explorer ID

Not Available

KNApSAcK ID

C00001927

BiGG ID

Not Available

BioCyc ID

Not Available

METLIN ID

Not Available

PDB ID

Not Available

Wikipedia Link

Tubocurarine_chloride

Chemspider ID

ChEBI ID

PubChem Compound ID

Kegg Compound ID

YMDB ID

Not Available

ECMDB ID

Not Available

References

Synthesis Reference

Not Available

MSDS

Link

General References

Youssef SA, Ramadan A, Afifi NA, Aziz MD: Influence of sodium taurocholate on the potency and duration of action of some neuromuscular blocking agents. Dtsch Tierarztl Wochenschr. 1991 Jun;98(6):213-6. [PubMed: 1889362]
Wikipedia. Curare. Last Updated 9 June 2009. - http://en.wikipedia.org/wiki/Curare

Tubocurarine (CED0003747)

Structure for CHEM002432: Tubocurarine

Structure