Clothianidin (CED0005696)

Record Information
Version1.0
Creation Date2013-04-25 07:56:50 UTC
Update Date2026-08-23 14:46:11 UTC
SynCED IDCED0005696
Secondary Accession Numbers
  • CHEM002776
  • T3D3815
Identification
Common NameClothianidin
ClassSmall Molecule
Description
Clothianidin is an exogenous solid with the formula C6H8ClN5O2S and an average molecular weight of 249.68 g/mol. Clothianidin belongs to the thiazoles, a subclass of azoles within the organic compounds. Biologically, it functions as a metabolite and a nicotinic agonist. It has been recorded to target eight proteins, including the neuronal acetylcholine receptor subunit alpha-2 (CHRNA2), the epidermal growth factor receptor (EGFR), cytochrome P450 2C9 (CYP2C9), and C-C motif chemokine 2 (CCL2). The compound is found in or released from nine recorded sources. In agriculture and land management, it is used in pesticides. Other sources include drinking water and water supply (specifically drinking water), food, food processing and cookware (including the treatment of hops and molasses and treatment of molasses), electrical and electronic equipment (such as television systems and antennas), and building and construction materials (including tents or canopies, sunshades awnings or outside screens, and floors). Recorded routes of exposure to the compound include oral and inhalation.
Contaminant Type
  • Amine
  • Insecticide
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Chemical Structure
Synonyms
ValueSource
(e)-N-(2-Chloro-5-thiazolyl)methyl-n'-methyl-n''-nitroguanidineChEBI
((e)-1-(2-chloro-1,3-Thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine)MeSH
Chemical FormulaC6H8ClN5O2S
Average Molecular Mass249.678 g/mol
Monoisotopic Mass249.009 g/mol
CAS Registry Number210880-92-5
IUPAC Name(E)-N'-[(2-chloro-1,3-thiazol-5-yl)methyl]-N-methyl-N''-nitroguanidine
Traditional Namecelero
SMILESCN\C(NCC1=CN=C(Cl)S1)=N/[N+]([O-])=O
InChI IdentifierInChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)
InChI KeyPGOOBECODWQEAB-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as 2,5-disubstituted thiazoles. 2,5-Disubstituted thiazoles are compounds containing a thiazole ring substituted at positions 2 and 5 only.
KingdomOrganic compounds
Super ClassOrganoheterocyclic compounds
ClassAzoles
Sub ClassThiazoles
Direct Parent2,5-disubstituted thiazoles
Alternative Parents
Substituents
  • 2,5-disubstituted 1,3-thiazole
  • Nitroguanidine
  • Aryl chloride
  • Aryl halide
  • Nitramine
  • Heteroaromatic compound
  • Guanidine
  • Organic nitro compound
  • Carboximidamide
  • Allyl-type 1,3-dipolar organic compound
  • Propargyl-type 1,3-dipolar organic compound
  • Organic 1,3-dipolar compound
  • Azacycle
  • Organic nitrogen compound
  • Organonitrogen compound
  • Organochloride
  • Organohalogen compound
  • Hydrocarbon derivative
  • Imine
  • Organic zwitterion
  • Organic oxygen compound
  • Organopnictogen compound
  • Organic oxide
  • Aromatic heteromonocyclic compound
Molecular FrameworkAromatic heteromonocyclic compounds
External Descriptors
Biological Properties
StatusDetected and Not Quantified
OriginExogenous
Cellular Locations
  • Cytoplasm
  • Extracellular
Biofluid LocationsNot Available
Tissue LocationsNot Available
Applications
Biological Roles
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateSolid
AppearanceWhite powder.
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted Properties
PropertyValueSource
Water Solubility0.11 g/LALOGPS
logP0.62ALOGPS
logP0.54ChemAxon
logS-3.4ALOGPS
pKa (Strongest Basic)0.41ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area92.45 ŲChemAxon
Rotatable Bond Count3ChemAxon
Refractivity55.53 m³·mol⁻¹ChemAxon
Polarizability22.17 ųChemAxon
Number of Rings1ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0910000000-6385f1a3a7f91ed7e982Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0gc0-0950000000-d29e3319f44939e2ffe7Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0159-0900000000-653b260bb023add99e31Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00lr-0900000000-b5f88b04d76924d17378Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-01q9-0900000000-ed2f06c069aed87e9f9eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03e9-0900000000-f9169babd128a490c689Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03e9-2900000000-84040d7ff64bca37fde8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0159-0900000000-97745f6dc45dd1581765Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0920000000-fec4e86ce184bd252665Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-02u0-0900000000-c422082c73e9f46c2713Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03e9-0900000000-d266e4d6dacfa337ada0Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0900000000-019d795fba7ac99240cfNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0gb9-0940000000-d3f42327bbe9eaebd932Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0159-0900000000-b753f5e40fab4c8f7092Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00lr-0900000000-c9321c59320cacc256daNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0900000000-11d29a227bda097d127cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0900000000-7e088dfb25fbf5322caeNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0159-0900000000-66c374cc807fdd5fc988Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-02t9-0910000000-6ad88fdea0ea1ddc8781Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0002-2290000000-644fadb6eee5601b9cabNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0aor-9500000000-09ac3a6ed1febac6eb66Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0aos-9640000000-c0c49ef1d0b9f0744dddNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0pb9-8900000000-dc704f45f9c0ead1de60Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-9000000000-e858eafc5134f3cf550eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-9000000000-e858eafc5134f3cf550eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014j-0930000000-6ac1af4e98bf8f7a4d2bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014j-0940000000-bc4db0ff85c5a89f943cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0gb9-0900000000-04c4695d00448356ddcaNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0002-0900000000-2af7fd1188a89eb40d4dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udj-0900000000-4ff1ff802897a01cecf8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udj-0900000000-4ff1ff802897a01cecf8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0159-0900000000-b753f5e40fab4c8f7092Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0gb9-0940000000-c737092c0956596a2df8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-9200000000-490db61798d1af3a9c0cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-9200000000-86a6b7f6dcddbcff2d3aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00lr-0900000000-c9321c59320cacc256daNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0900000000-11d29a227bda097d127cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-9100000000-60267f4ffd9a625737f7Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0gb9-0900000000-04c4695d00448356ddcaNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-02ai-0900000000-d59b13c1379eaa6411b9Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0159-0900000000-fe3389ac5c6af64c692cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0002-0900000000-2af7fd1188a89eb40d4dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014j-0940000000-bc4db0ff85c5a89f943cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03e9-0900000000-e20dc9da12d7b8427f9bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0900000000-53a14facdf4fbf1d8659Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0900000000-768e862b2ae59c13b999Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-9100000000-eacdb9668fcb7596fa8cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-5900000000-724d9b096d9c21a153ebNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-02t9-0910000000-6ad88fdea0ea1ddc8781Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0gc0-0950000000-d29e3319f44939e2ffe7Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0pba-6900000000-bdd0bf54bd05235ab7f4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4j-9400000000-eb6e010f8916186ab8e0Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0910000000-6385f1a3a7f91ed7e982Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0159-0900000000-97745f6dc45dd1581765Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03e9-2900000000-e3d57f4605023197fa68Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0910000000-00d9fc49ea58e8efd8efNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00lr-0900000000-b5f88b04d76924d17378Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00lr-0900000000-7d0576e439e8aac8d66dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0159-0900000000-a43628ffd70a03fb5e71Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0159-0900000000-653b260bb023add99e31Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-01q9-0900000000-23fd982992acce27117dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-01q9-0900000000-ed2f06c069aed87e9f9eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03e9-0900000000-f9169babd128a490c689Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03e9-0900000000-aa54e4eabd29ed96bc3eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0pb9-8900000000-dc704f45f9c0ead1de60Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0aos-9640000000-c0c49ef1d0b9f0744dddNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0gc0-0950000000-d7eeca247a9f78479dd2Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-9000000000-e858eafc5134f3cf550eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03e9-2900000000-84040d7ff64bca37fde8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0002-2290000000-644fadb6eee5601b9cabNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-066r-5900000000-6ba27f1792e180378b94Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0aor-9700000000-5f09fedbe94253443c64Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0aor-9500000000-09ac3a6ed1febac6eb66Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014j-0930000000-6ac1af4e98bf8f7a4d2bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0002-1290000000-6f3067b9cd5ae22a451cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03e9-0900000000-ab148c09e5495285459fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03e9-2900000000-c17677c0c506719ce55dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-9000000000-38fde8bccf58d8e98c4dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03e9-2900000000-770642b3e05f64ae869cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014j-0940000000-c0d8cb5253dacf7906a3Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-001i-0900000000-f0fea29def23ca0fa67cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-9100000000-c01510a7cc0da400c22dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0a4i-9100000000-2439e3d9a77b91bcd6afNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-5900000000-0f7adbdd8fbd7d4f0669Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0udi-0090000000-cf623673de668657f311Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0udl-0190000000-392883a85c2c2015b0c3Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-044i-9500000000-499b35d8d5d2f169387dNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0002-4090000000-770d5ba68ba065242bf7Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0002-2190000000-82b6362d6ef9385de1d2Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0bti-9200000000-2b339e51e2cf38532f75Not AvailableView Spectrum
Toxicity Profile
Toxicity Values
Toxicity ValueOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalToxicity RatingReference
2009.0 Log mg/kg [1100:3600]RatLD50oralpredictedNot AvailableNot Available
250.0 mg/kg-day MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
50.0 mg/kg-day MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
10.0 mg/kg-day MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
250.0 mg/kg-day MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
24.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
2.0 mg/kg-day RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
8.0 mg/kg-day RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
8.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
2.0 mg/kg-day RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
2.0 mg/kg-day RatNOELoralexperimentalNot AvailableECOTOX - EPA ORD
32.0 mg/kg-day RatLOELoralexperimentalNot AvailableECOTOX - EPA ORD
17.31 mg/kg-day MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
17.31 mg/kg-day MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
17.31 mg/kg-day MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
17.31 mg/kg-day MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
3.84 mg/kg-day MouseLOELoralexperimentalNot AvailableECOTOX - EPA ORD
28.61 mg/kg-day MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
28.61 mg/kg-day MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
28.61 mg/kg-day MouseNOELoralexperimentalNot AvailableECOTOX - EPA ORD
Toxicity / Toxin ClassNot Available
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)No indication of carcinogenicity to humans (not listed by IARC).
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Health Effects
Health EffectRelationshipDirectionDescriptionReference
Immunosuppression TherapyAssociated With?decreaseNot AvailablePMC8675359
DysbiosisAssociated With?Not AvailableNot AvailablePMC8619528
Exposure Sources
Source IDSourceSectorReference
CEDs000007Pesticides?Pesticides are synthetic chemicals designed to prevent, destroy, or control pests that threaten crops and agricultural productivity.Agriculture & land managementNot Available
CEDs000010Insecticides?Insecticides are synthetic chemicals designed to control or eliminate insect pests that threaten crops and other agricultural products.Agriculture & land managementPubChem
CEDs000013Soil?Soil serves as a critical medium for plant growth and sustains various ecological functions; however, it can become a reservoir for synthetic chemical contamination.Agriculture & land managementPMC13053340 , PMC5363855
CEDs000017Atmospheric particulate matter?Atmospheric particulate matter (PM) consists of tiny solid or liquid particles suspended in the air, which can originate from various sources, including industrial emissions, vehicle exhaust, and natural processes.Air, dust & atmospheric transportPMC8235395
CEDs000051Surface water?Surface water can serve as a significant vector for the introduction of synthetic chemical contaminants into aquatic ecosystems.Aquatic systems & sedimentsPMC5363855 , PMC7878760
CEDs000070Stormwater runoff?Stormwater runoff refers to the flow of rainwater or melted snow that does not soak into the ground and instead collects pollutants as it travels over impervious surfaces such as roads and parking lots.Automotive & urban infrastructurePubChem
CEDs000115Drinking water?Drinking water can be a medium for synthetic chemical contamination, often originating from various industrial processes and agricultural practices.Drinking water & water supplyPMC13226431
CEDs000116Tap water?Tap water can be a potential source of synthetic chemical contamination due to various industrial processes and agricultural runoff.Drinking water & water supplyPMC9431852 , PMC6797178
CEDs000233Brushes?Brushes used in personal care and cosmetics can be a source of synthetic chemical contamination due to the materials and coatings used in their manufacturing.Personal care & cosmeticsPubChem
CEDs000479Effluent?Effluent refers to liquid waste or sewage that is discharged into the environment, typically resulting from industrial processes, municipal wastewater treatment, or agricultural runoff.Wastewater, sanitation & biosolidsPMC12723015 , PMC12723015
CEDs000497Floors?Floors in built environments can be a significant source of synthetic chemical contamination due to the materials and finishes used in their construction.Building & ConstructionPubChem
CEDs000502Sunshades Awnings Or Outside Screens?Sunshades, awnings, and outside screens are commonly used in construction to enhance energy efficiency and provide shade.Building & ConstructionPubChem
CEDs000503Tents Or Canopies?Tents and canopies used in various applications can be a source of synthetic chemical contamination primarily due to the materials from which they are made.Building & ConstructionPubChem
CEDs000506Antennas?Antennas, commonly used in communication technologies, can be a source of synthetic chemical contamination through the materials and coatings used in their construction.Electrical & Electronic EquipmentPubChem
CEDs000511Conductors Or Conductive Bodies Characterised By The Conductive Materials?Conductors, or conductive bodies, are materials that allow the flow of electrical current, typically made from metals such as copper, aluminum, or silver.Electrical & Electronic EquipmentPubChem
CEDs000517Electric Switches?Electric switches, integral components in numerous devices, can be a source of synthetic chemical contamination due to the materials and manufacturing processes involved in their production.Electrical & Electronic EquipmentPubChem
CEDs000518Electrically Stimulated Smoking Devices?Electrically stimulated smoking devices, commonly known as e-cigarettes or vape pens, utilize electrical components to heat a liquid solution, often containing nicotine, flavorings, and other additives, to produce an aerosol for inhalation.Electrical & Electronic EquipmentPubChem
CEDs000524Hybrid Capacitors?Hybrid capacitors are energy storage devices that combine the properties of electrolytic and supercapacitors, utilizing a combination of electrochemical principles to achieve higher energy density and power density.Electrical & Electronic EquipmentPubChem
CEDs000537Television Systems?Television systems can be a source of synthetic chemical contamination due to the various materials and components used in their manufacture and operation.Electrical & Electronic EquipmentPubChem
CEDs000539Video Games?Video games, through their production and disposal processes, can be a source of synthetic chemical contamination.Electrical & Electronic EquipmentPubChem
CEDs000545Food Preservation?Food preservation often involves the use of synthetic chemicals, such as preservatives, flavor enhancers, and color additives, to extend shelf life and enhance the sensory qualities of food products.Food, food processing & cookwarePubChem
CEDs000546Molasses And Treatment Of Molasses?Molasses is a thick, viscous byproduct of sugar production, derived from the extraction of sugar cane or sugar beet juice.Food, food processing & cookwarePubChem
CEDs000552Processing Meats?Processing meats can lead to synthetic chemical contamination primarily through the use of additives and preservatives.Food, food processing & cookwarePubChem
CEDs000553Treatment Of Hops?Hops, a key ingredient in brewing and food flavoring, can be a source of synthetic chemical contamination due to various agricultural practices.Food, food processing & cookwarePubChem
CEDs000556Cigar Cigarettes?Cigar cigarettes are a source of synthetic chemical contamination due to the combustion of various tobacco blends and additives.Household cleaning & consumer productsPubChem
CEDs000561Perfumes Within Detergents And Soaps?Perfumes within detergents and soaps are synthetic fragrance compounds added to enhance the sensory experience of cleaning products.Household cleaning & consumer productsPubChem
CEDs000563Soap Detergents?Soap detergents are synthetic surfactants designed to enhance the cleaning efficacy of water by reducing surface tension, allowing for better interaction with dirt and grease.Household cleaning & consumer productsPubChem
CEDs000569Tobacco Smoke Filters?Tobacco smoke filters are designed to reduce the inhalation of harmful substances in cigarette smoke, including tar and other particulate matter.Household cleaning & consumer productsPubChem
CEDs000578Making Cigars?The process of making cigars involves several steps, including the cultivation of tobacco, fermentation, and the application of various additives to enhance flavor and preservation.Industrial manufacturing & chemical processingPubChem
CEDs000580Manufacture Preparation Of Tobacco Products?The manufacture and preparation of tobacco products involve various processes that can result in the introduction of synthetic chemicals into the environment.Industrial manufacturing & chemical processingPubChem
CEDs000581Paper Making Machines?Paper making machines utilize various synthetic chemicals throughout the production process, including additives, coatings, and bleaching agents.Industrial manufacturing & chemical processingPubChem
CEDs000592Marine Propulsion Or Steering?Marine propulsion and steering systems often rely on various synthetic chemicals, including lubricants, fuels, and hydraulic fluids.Marine, shipping & aquaculturePubChem
CEDs000596Acaricides?Acaricides are synthetic chemicals specifically designed to target and control mite populations that can damage crops and plants.Agriculture & land managementPubChem
CEDs000597Chemosterilants?Chemosterilants are synthetic chemicals designed to induce sterility in target pest populations, thereby controlling their reproduction and mitigating damage to crops.Agriculture & land managementPubChem
CEDs000598Fertiliser Distributors?Fertiliser distributors play a critical role in the supply of synthetic fertilizers, which are widely used to enhance soil fertility and crop yield.Agriculture & land managementPubChem
CEDs000600Herbicides And Algicides?Herbicides and algicides are synthetic chemicals primarily used to control unwanted plants and algae in various environments.Agriculture & land managementPubChem
CEDs000601Lawn Mowers?Lawn mowers, particularly those powered by gasoline, can be a source of synthetic chemical contamination due to the combustion of fossil fuels and the use of engine oils.Agriculture & land managementPubChem
CEDs000602Molluscicides?Molluscicides are synthetic chemicals specifically designed to control and eliminate mollusks, such as snails and slugs, which can be detrimental to crops and agricultural productivity.Agriculture & land managementPubChem
CEDs000603Nematocides?Nematocides are synthetic chemicals specifically designed to control nematodes, which are microscopic roundworms that can cause significant damage to crops and plants.Agriculture & land managementPubChem
CEDs000604Pest Attractants?Pest attractants are synthetic chemicals designed to lure specific pests for monitoring or control purposes.Agriculture & land managementPubChem
CEDs000605Pest Repellants?Pest repellents, often formulated from synthetic chemicals, are widely used to protect crops from insect infestations and other pests.Agriculture & land managementPubChem
CEDs000606Plant Growth Regulators?Plant Growth Regulators (PGRs) are synthetic chemicals designed to influence the growth and development of plants.Agriculture & land managementPubChem
CEDs000607Rodenticides(1)?Rodenticides are synthetic chemicals specifically formulated to control rodent populations, serving as a crucial tool in managing pests that can damage crops and spread diseases.Agriculture & land managementPubChem
CEDs000608Rodenticides?Rodenticides are chemical substances specifically designed to control rodent populations by causing death through various mechanisms, including anticoagulation or neurotoxicity.Agriculture & land managementPubChem
CEDs000609Aftershave?Aftershave is a grooming product typically used to soothe and protect the skin following shaving.Personal care & cosmeticsPubChem
CEDs000611Anti Perspirants Or Body Deoderants?Antiperspirants and body deodorants commonly contain synthetic chemicals such as aluminum compounds, parabens, and synthetic fragrances.Personal care & cosmeticsPubChem
CEDs000612Body Washing Or Cleaning Implements?Body washing or cleaning implements, such as synthetic sponges, loofahs, and washcloths, can be sources of synthetic chemical contamination due to the materials used in their production.Personal care & cosmeticsPubChem
CEDs000614Essential Oils Or Perfumes?Essential oils and perfumes are complex mixtures of volatile compounds derived from natural or synthetic sources, commonly used for their aromatic properties.Personal care & cosmeticsPubChem
CEDs000615Eye Makeup Products?Eye makeup products, including mascaras, eyeliners, and eyeshadows, often contain a variety of synthetic chemicals such as pigments, preservatives, and film-forming agents.Personal care & cosmeticsPubChem
CEDs000616Face Mask Cosmetics?Face mask cosmetics often contain a variety of synthetic chemicals, including preservatives, emulsifiers, and fragrances, which can contribute to chemical contamination.Personal care & cosmeticsPubChem
CEDs000617Lip Care Products?Lip care products, including lipsticks, balms, and glosses, often contain a variety of synthetic chemicals such as parabens, phthalates, and synthetic fragrances.Personal care & cosmeticsPubChem
CEDs000618Lip Makeup Products?Lip makeup products, such as lipsticks, lip glosses, and lip liners, often contain a variety of synthetic chemicals, including pigments, preservatives, and emollients.Personal care & cosmeticsPubChem
CEDs000630Toys?Toys, particularly those made from synthetic materials such as plastics, can be a source of chemical contamination due to the presence of various additives and compounds used in their production.Recreation & sports surfacesPubChem
CEDs000632Apparel?Apparel production often involves the use of various synthetic chemicals, including dyes, finishing agents, and preservatives.Textiles, leather & furnishingsPubChem
CEDs000634Buckles?Buckles, commonly used as fasteners in clothing, accessories, and furniture, can be a source of synthetic chemical contamination due to the materials and coatings employed in their production.Textiles, leather & furnishingsPubChem
CEDs000638Decorating Textiles?Decorating textiles often involves the use of synthetic chemicals such as dyes, finishes, and coatings.Textiles, leather & furnishingsPubChem
CEDs000642Footwear?Footwear production often involves the use of various synthetic chemicals, such as adhesives, dyes, and treatments, which can contribute to environmental contamination.Textiles, leather & furnishingsPubChem
CEDs000643Headwear?Headwear made from synthetic materials often incorporates chemicals used in the manufacturing and finishing processes, such as dyes, flame retardants, and water repellents.Textiles, leather & furnishingsPubChem
CEDs000650Purses Luggage Hand Bags?Purses, luggage, and handbags are often manufactured using synthetic materials such as polyvinyl chloride (PVC), polyurethane, and various types of nylon.Textiles, leather & furnishingsPubChem
CEDs000652Ropes?Ropes manufactured from synthetic fibers, such as polypropylene, nylon, and polyester, are widely used in various applications, including marine, construction, and outdoor activities.Textiles, leather & furnishingsPubChem
CEDs000659Transfer Printing?Transfer printing is a process used to apply designs and patterns onto various substrates, commonly utilizing synthetic dyes and inks that can contain hazardous chemicals.Textiles, leather & furnishingsPubChem
CEDs000662Yarns Or Threads?Yarns or threads used in textiles can be a source of synthetic chemical contamination due to the production processes and treatments they undergo.Textiles, leather & furnishingsPubChem
CEDs000665Fire Extinguishers?Fire extinguishers contain various synthetic chemicals designed to suppress flames and prevent the spread of fire.Fire suppression systems & agentsPubChem
CEDs000671Airplanes And Helicopters?Airplanes and helicopters are significant sources of synthetic chemical contamination primarily through the use of aviation fuels, lubricants, and de-icing agents.Aviation & AerospacePubChem
CEDs000673Unmanned Aerial Vehicles?Unmanned Aerial Vehicles (UAVs), commonly known as drones, utilize various synthetic chemicals in their manufacturing, operation, and maintenance processes.Aviation & AerospacePubChem
CEDs000678Nitrogenous Fertilisers?Nitrogenous fertilizers are synthetic chemical compounds primarily used to enhance plant growth by supplying essential nitrogen, a crucial nutrient for photosynthesis and protein synthesis.Agriculture & land managementPubChem
CEDs000679Phosphatic Fertilisers?Phosphatic fertilizers are synthetic chemical products primarily composed of phosphorus, which is essential for plant growth.Agriculture & land managementPubChem
CEDs000685Ceramics?Ceramics can be a source of synthetic chemical contamination through various additives and processing agents used in their production.Building & ConstructionPubChem
CEDs000696Nanotechnology?Nanotechnology involves the manipulation of materials at the molecular or atomic level, typically within the range of 1 to 100 nanometers.Industrial manufacturing & chemical processingPubChem
CEDs000698Jewellery?Jewellery production often involves the use of various synthetic chemicals during the extraction and processing of metals.Mining & metal processingPubChem
CEDs000726Pens?Pens, commonly utilized for writing and marking, can be a source of synthetic chemical contamination primarily due to the materials used in their manufacturing.Paper, pulp & fiber productsPubChem
CEDs000727Printing Machines Or Presses?Printing machines or presses commonly utilize synthetic chemicals such as inks, solvents, and cleaning agents.Paper, pulp & fiber productsPubChem
CEDs000733Walking Sticks?Walking sticks, while primarily designed for mobility assistance, can be sources of synthetic chemical contamination if not properly manufactured or maintained.Healthcare, pharmaceuticals & veterinary productsPubChem
CEDs000735Explosives?Explosives are chemical compounds or mixtures designed to undergo rapid decomposition, releasing energy in the form of gas and heat.Defense & military infrastructurePubChem
CEDs000738Cooling Circuit Water?Cooling circuit water is utilized in various industrial processes to absorb and dissipate heat generated during operations.Industrial manufacturing & chemical processingPubChem
CEDs000739Inks?Inks are complex mixtures composed of pigments or dyes, solvents, resins, and additives used primarily for printing and writing applications.Paper, pulp & fiber productsPubChem
CEDs000740Paper?Paper production involves the processing of wood fibers and the use of various chemicals, which can lead to synthetic chemical contamination.Paper, pulp & fiber productsPubChem
CEDs000741Pigment Pastes?Pigment pastes are concentrated dispersions of pigments used to impart color and properties to materials.Paper, pulp & fiber productsPubChem
CEDs000743Sludge Treatment?Sludge treatment involves the processing of waste materials generated from wastewater treatment plants, which often contain a variety of organic and inorganic substances.Wastewater, sanitation & biosolidsPubChem
CEDs000744Water, Wastewater, & Sewage Treatment?Water, wastewater, and sewage treatment processes are critical for managing and mitigating pollutants in water systems.Wastewater, sanitation & biosolidsPubChem
CEDs00753Agricultural SoilAgriculture & land managementPMC10648468 , PMC6421824
CEDs00758Agricultural FieldAgriculture & land managementPMC13053340
CEDs00829Agricultural RunoffAgriculture & land managementPMC9878729
CEDs00906Dry SoilAgriculture & land managementPMC13053340
CEDs01148MilkFood, food processing & cookwarePMC10048192
CEDs01153Breast MilkFood, food processing & cookwarePMC10048192
CEDs01170EggsFood, food processing & cookwarePMC4871908
CEDs01198HoneyFood, food processing & cookwarePMC11996992
CEDs01199Honey SamplesFood, food processing & cookwarePMC13352592 , PMC7996329
CEDs01200VegetablesFood, food processing & cookwarePMC12694491
CEDs01208FruitFood, food processing & cookwarePMC13464434
CEDs01276Food SamplesFood, food processing & cookwarePMC13209692
CEDs01279Vegetable SamplesFood, food processing & cookwarePMC13464434
CEDs01312Sugar WaterFood, food processing & cookwarePMC6723792
CEDs01415HoneydewFood, food processing & cookwarePMC9299500
CEDs01522Green CoffeeFood, food processing & cookwarePMC12073578
CEDs01673BeebreadFood, food processing & cookwarePMC4284396
CEDs01879ResinIndustrial manufacturing & chemical processingPMC12970513
CEDs02222Finished Drinking WaterDrinking water & water supplyPMC9431852
CEDs02224Well WaterDrinking water & water supplyPMC5363855 , PMC5363855
CEDs02255WaterAquatic systems & sedimentsPMC5363855 , PMC5363855
CEDs02264SedimentAquatic systems & sedimentsPMC5363855
CEDs02268Water SamplesAquatic systems & sedimentsPMC12165005 , PMC5363855
CEDs02270RiverAquatic systems & sedimentsPMC10772579 , PMC9928825
CEDs02276Aquatic EnvironmentAquatic systems & sedimentsPMC11277666
CEDs02281Water SampleAquatic systems & sedimentsPMC6449027
CEDs02289StreamAquatic systems & sedimentsPMC6449027 , PMC9431852
CEDs02334Pond WaterAquatic systems & sedimentsPMC6797178
CEDs02590DustAir, dust & atmospheric transportPMC10648468
CEDs02634Air SamplesAir, dust & atmospheric transportPMC10648468
CEDs02698Surface DustAir, dust & atmospheric transportPMC10648468 , PMC10648468
CEDs03009Waste WaterWastewater, sanitation & biosolidsPMC12775120 , PMC8675359
CEDs03282RunoffAutomotive & urban infrastructurePMC12303642
CEDs03289StormwaterAutomotive & urban infrastructurePMC12303642
CEDs03336Urban StormwaterAutomotive & urban infrastructurePMC12303642
Pathways
0 pathwaysPathway Source: PathBank

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Acetylcholinesterase structureClick to view 3D structureAcetylcholinesteraseP22303HumansKnownNot Available
Click to view 3D structureAcetylcholine receptor subunit beta-like 2P25162Drosophila melanogasterPredicted (SEA)
Prediction Confidence Score
0.433
Applicability Domain
1.0
Statistical Significance
6.00e-05
Supporting Reference Compounds
13
E-value
0.467095
Click to view 3D structureNicotinic acetylcholine receptor alpha 5 subunitA9XFY4Musca domesticaPredicted (SEA)
Prediction Confidence Score
0.375
Applicability Domain
1.0
Statistical Significance
5.00e-05
Supporting Reference Compounds
10
E-value
0.389246
Click to view 3D structureNicotinic acetylcholine receptor alpha8 subunitH6TY12Periplaneta americanaPredicted (SEA)
Prediction Confidence Score
0.32
Applicability Domain
1.0
Statistical Significance
6.00e-05
Supporting Reference Compounds
5
E-value
0.467095
Tyrosine-protein kinase Lck structureClick to view 3D structureTyrosine-protein kinase LckP06239HumansPredicted (SEA)
Prediction Confidence Score
0.244
Applicability Domain
0.279 Low confidence
Statistical Significance
0.4601
Supporting Reference Compounds
1130
E-value
3582.08
Glycogen synthase kinase-3 beta structureClick to view 3D structureGlycogen synthase kinase-3 betaP49841HumansPredicted (SEA)
Prediction Confidence Score
0.238
Applicability Domain
0.279 Low confidence
Statistical Significance
0.5208
Supporting Reference Compounds
1157
E-value
4054.7
Cyclin-dependent kinase 2 structureClick to view 3D structureCyclin-dependent kinase 2P24941HumansPredicted (SEA)
Prediction Confidence Score
0.238
Applicability Domain
0.279 Low confidence
Statistical Significance
0.4752
Supporting Reference Compounds
1029
E-value
3699.55
Vascular endothelial growth factor receptor 1 structureClick to view 3D structureVascular endothelial growth factor receptor 1P17948HumansPredicted (SEA)
Prediction Confidence Score
0.237
Applicability Domain
0.277 Low confidence
Statistical Significance
0.4191
Supporting Reference Compounds
711
E-value
3262.51
RAC-gamma serine/threonine-protein kinase structureClick to view 3D structureRAC-gamma serine/threonine-protein kinaseQ9Y243HumansPredicted (SEA)
Prediction Confidence Score
0.237
Applicability Domain
0.279 Low confidence
Statistical Significance
0.3972
Supporting Reference Compounds
620
E-value
3092.25
Tyrosine-protein kinase JAK2 structureClick to view 3D structureTyrosine-protein kinase JAK2O60674HumansPredicted (SEA)
Prediction Confidence Score
0.235
Applicability Domain
0.279 Low confidence
Statistical Significance
0.5325
Supporting Reference Compounds
1022
E-value
4145.63
Mitogen-activated protein kinase 8 structureClick to view 3D structureMitogen-activated protein kinase 8P45983HumansPredicted (SEA)
Prediction Confidence Score
0.235
Applicability Domain
0.279 Low confidence
Statistical Significance
0.4882
Supporting Reference Compounds
782
E-value
3800.44
Aurora kinase A structureClick to view 3D structureAurora kinase AO14965HumansPredicted (SEA)
Prediction Confidence Score
0.235
Applicability Domain
0.279 Low confidence
Statistical Significance
0.5077
Supporting Reference Compounds
996
E-value
3952.41
Vascular endothelial growth factor receptor 2 structureClick to view 3D structureVascular endothelial growth factor receptor 2P35968HumansPredicted (SEA)
Prediction Confidence Score
0.235
Applicability Domain
0.279 Low confidence
Statistical Significance
0.5975
Supporting Reference Compounds
1660
E-value
4651.34
Insulin receptor structureClick to view 3D structureInsulin receptorP06213HumansPredicted (SEA)
Prediction Confidence Score
0.235
Applicability Domain
0.279 Low confidence
Statistical Significance
0.4654
Supporting Reference Compounds
772
E-value
3623.18
Rho-associated protein kinase 1 structureClick to view 3D structureRho-associated protein kinase 1Q13464HumansPredicted (SEA)
Prediction Confidence Score
0.235
Applicability Domain
0.279 Low confidence
Statistical Significance
0.4878
Supporting Reference Compounds
834
E-value
3797.41
RAC-alpha serine/threonine-protein kinase structureClick to view 3D structureRAC-alpha serine/threonine-protein kinaseP31749HumansPredicted (SEA)
Prediction Confidence Score
0.235
Applicability Domain
0.279 Low confidence
Statistical Significance
0.4738
Supporting Reference Compounds
797
E-value
3688.57
Epidermal growth factor receptor structureClick to view 3D structureEpidermal growth factor receptorP00533HumansPredicted (SEA)
Prediction Confidence Score
0.235
Applicability Domain
0.279 Low confidence
Statistical Significance
0.5708
Supporting Reference Compounds
1301
E-value
4444.02
Tyrosine-protein kinase ITK/TSK structureClick to view 3D structureTyrosine-protein kinase ITK/TSKQ08881HumansPredicted (SEA)
Prediction Confidence Score
0.235
Applicability Domain
0.279 Low confidence
Statistical Significance
0.399
Supporting Reference Compounds
570
E-value
3106.34
RAC-beta serine/threonine-protein kinase structureClick to view 3D structureRAC-beta serine/threonine-protein kinaseP31751HumansPredicted (SEA)
Prediction Confidence Score
0.235
Applicability Domain
0.279 Low confidence
Statistical Significance
0.4123
Supporting Reference Compounds
631
E-value
3209.8
Serine/threonine-protein kinase PAK 1 structureClick to view 3D structureSerine/threonine-protein kinase PAK 1Q13153HumansPredicted (SEA)
Prediction Confidence Score
0.235
Applicability Domain
0.279 Low confidence
Statistical Significance
0.411
Supporting Reference Compounds
595
E-value
3199.91
Fibroblast growth factor receptor 1 structureClick to view 3D structureFibroblast growth factor receptor 1P11362HumansPredicted (SEA)
Prediction Confidence Score
0.233
Applicability Domain
0.279 Low confidence
Statistical Significance
0.5251
Supporting Reference Compounds
1010
E-value
4088.17
Serine/threonine-protein kinase PAK 4 structureClick to view 3D structureSerine/threonine-protein kinase PAK 4O96013HumansPredicted (SEA)
Prediction Confidence Score
0.233
Applicability Domain
0.279 Low confidence
Statistical Significance
0.4673
Supporting Reference Compounds
728
E-value
3637.58
Tyrosine-protein kinase JAK3 structureClick to view 3D structureTyrosine-protein kinase JAK3P52333HumansPredicted (SEA)
Prediction Confidence Score
0.233
Applicability Domain
0.279 Low confidence
Statistical Significance
0.5239
Supporting Reference Compounds
961
E-value
4078.83
High affinity nerve growth factor receptor structureClick to view 3D structureHigh affinity nerve growth factor receptorP04629HumansPredicted (SEA)
Prediction Confidence Score
0.233
Applicability Domain
0.279 Low confidence
Statistical Significance
0.5134
Supporting Reference Compounds
869
E-value
3997.01
BDNF/NT-3 growth factors receptor structureClick to view 3D structureBDNF/NT-3 growth factors receptorQ16620HumansPredicted (SEA)
Prediction Confidence Score
0.233
Applicability Domain
0.279 Low confidence
Statistical Significance
0.4748
Supporting Reference Compounds
721
E-value
3696.13
Tyrosine-protein kinase Fyn structureClick to view 3D structureTyrosine-protein kinase FynP06241HumansPredicted (SEA)
Prediction Confidence Score
0.233
Applicability Domain
0.279 Low confidence
Statistical Significance
0.4662
Supporting Reference Compounds
707
E-value
3629.33
Cytochrome P450 2C9 structureClick to view 3D structureCytochrome P450 2C9P11712HumansKnownNot Available
E-selectin structureClick to view 3D structureE-selectinP16581HumansKnownNot Available
Epidermal growth factor receptor structureClick to view 3D structureEpidermal growth factor receptorP00533HumansKnownNot Available
Matrix metalloproteinase-9 structureClick to view 3D structureMatrix metalloproteinase-9P14780HumansKnownNot Available
Nuclear receptor subfamily 1 group I member 2 structureClick to view 3D structureNuclear receptor subfamily 1 group I member 2O75469HumansKnownNot Available
C-C motif chemokine 2 structureClick to view 3D structureC-C motif chemokine 2P13500HumansKnownNot Available
Urokinase plasminogen activator surface receptor structureClick to view 3D structureUrokinase plasminogen activator surface receptorQ03405HumansKnownNot Available
Neuronal acetylcholine receptor subunit alpha-2 structureClick to view 3D structureNeuronal acetylcholine receptor subunit alpha-2Q15822HumansKnownNot Available
Concentrations
Not Available
External Links
DrugBank IDNot Available
HMDB IDNot Available
FooDB IDNot Available
Phenol Explorer IDNot Available
KNApSAcK IDNot Available
BiGG IDNot Available
BioCyc IDNot Available
METLIN IDNot Available
PDB IDNot Available
Wikipedia LinkClothianidin
Chemspider IDNot Available
ChEBI ID39177
PubChem Compound ID213027
Kegg Compound IDC18508
YMDB IDNot Available
ECMDB IDNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available