HESPERIDIN (CED0002510)

HESPERIDIN belongs to the flavonoid glycosides, a subclass of flavonoids within the organic compounds. With an average molecular weight of 610.56 g/mol, HESPERIDIN is a heavy molecule with the chemical formula C28H34O15. It is categorized within the superclass of phenylpropanoids and polyketides. Biologically, the compound acts as an antioxidant (PMC10812391, PMC11548494, PMC11643819, PMC13207936, PMC13360740, PMC8819208) and a drug (PMC7895681). Industrially, it is utilized as a softener, conditioner, flavouring, and nutrient (PMC10812391, PMC11548494, PMC11643819, PMC13207936, PMC13360740, PMC8819208). The compound is found in 19 recorded sources, including drinking water and building and construction materials such as ceilings and fencing. It is also present in household cleaning and consumer products, including soap detergents, perfumes within detergents and soaps, cigar cigarettes, non electric simulated smoking devices, and other smoking requisites. Additionally, it is associated with electrical and electronic equipment, such as video games, electrodes, electrically stimulated smoking devices, and conductors or conductive bodies characterised by the conductive materials. It is also found in food, food processing and cookware, including food preservation, fermentation processes for beer, the preparation of vinegar, the preparation of wine or sparkling wine, and the processing of fish. The recorded exposure route is oral. HESPERIDIN targets two proteins: the voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B) and the Aurora kinase B (AURKB), of which it is an inhibitor or regulator. Regarding health effects, it is associated with inflammation (PMC10812391) but also provides a therapeutic effect on inflammation (PMC13480764) and hyperglycemia (PMC8398118). Furthermore, it is used as a treatment for diabetes mellitus (PMC10646315).