Trifluoroacetic acid (CED0001090)

Trifluoroacetic acid (C2HF3O2) has an average molecular weight of 114.02 g/mol. Trifluoroacetic acid belongs to the alpha-halocarboxylic acids and derivatives, a subclass of carboxylic acids and derivatives within the organic compounds. This compound serves several industrial roles, acting as an acid (PMC10552653), additive (PMC10552653), catalyst (PMC6384868), and solvent (PMC11678251, PMC13234783). In biological contexts, it is used as a drug (PMC8227162), ligand (PMC13234783), and biomarker (PMC13257718). Additionally, it is used in Polyamide plastics. Trifluoroacetic acid is found in or released from 43 recorded sources. These include electrical and electronic equipment, such as antennas, discharge lamps, contacts, conductors or conductive bodies characterised by the conductive materials, and auxiliary devices. It is present in household cleaning and consumer products, including soap detergents, perfumes within detergents and soaps, bleaching agents, cigar cigarettes, and non electric simulated smoking devices. Environmental sources include aquatic systems and sediments—specifically seawater, freshwater, surface water, and groundwater—as well as drinking water and water supply, including bottled, desalinated, tap, and drinking water. It is also found in wastewater, sanitation and biosolids, including mine wastewater, industrial wastewater, wastewater treatment effluent, and unspecified wastewater. Other sources include food, food processing and cookware, specifically food preservation, food contact materials, and fermentation processes for beer, among five more sectors. Exposure routes include touch, oral, and inhalation. Health effects associated with trifluoroacetic acid include inflammation (PMC2639783), thrombosis (PMC2639783), weight gain (PMC2639783), arrhythmia (PMC2639783), and myocardial infarction (PMC2639783).