Actinomycin D (CED0001480)

Actinomycin D is a compound with the chemical formula C10H12O2 and an average molecular weight of 164.20 g/mol. Actinomycin D belongs to the benzoic acids and derivatives, a subclass of benzene and substituted derivatives within the organic compounds. This substance is found in or released from 13 recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is used as antibiotics and antineoplastic agents. It is also associated with food preservation and food contact materials. Other recorded sources include ladders in building and construction, as well as household cleaning and consumer products such as pipe accessories, tobacco smoke filters, and perfumes within detergents and soaps. Additionally, it is found in electrical and electronic equipment, specifically electrodes, thin magnetic films, electric hearing aids, conductors or conductive bodies characterised by the conductive materials, and antennas. Recorded exposure routes for the compound include oral, intravenous, inhalation, and touch. At the molecular level, Actinomycin D acts on three recorded protein targets. It serves as an inhibitor of DNA topoisomerase 1 (TOP1), DNA topoisomerase 2-alpha (TOP2A), and DNA topoisomerase 2-beta (TOP2B).