5-Aminosalicylic acid (CED0002522)

5-Aminosalicylic acid is an organic compound with the formula C7H7NO3 and an average molecular weight of 153.14 g/mol. 5-Aminosalicylic acid belongs to the benzoic acids and derivatives, a subclass of benzene and substituted derivatives within the organic compounds. It is utilized as an intestinal antiinflammatory agent within the category of healthcare, pharmaceuticals, and veterinary products. The compound is found in or released from 22 recorded sources. These include drinking water and water supply, ceilings in building and construction, and food, food processing and cookware, specifically in the preparation of malt, food preservation, and fermentation processes for beer. It is also associated with household cleaning and consumer products, such as bleaching agents, perfumes within detergents and soaps, cigar cigarettes, non electric simulated smoking devices, and other smoking requisites. Additionally, it is linked to electrical and electronic equipment, including electrodes, fixed capacitors and their manufacture, antennas, conductors or conductive bodies characterised by the conductive materials, and electrically stimulated smoking devices, among 4 other sources. Recorded exposure routes for the substance are rectal and oral. At the molecular level, 5-Aminosalicylic acid interacts with 7 recorded protein targets. It acts as an agonist or inhibitor of Prostaglandin G/H synthase 1 (PTGS1) and Prostaglandin G/H synthase 2 (PTGS2). Other protein targets include Peroxisome proliferator-activated receptor gamma (PPARG), Inhibitor of nuclear factor kappa-B kinase subunit alpha (CHUK), and 3 other proteins.