Metoclopramide (CED0002413)

Metoclopramide is an organic compound with the formula C14H22ClN3O2 and an average molecular weight of 299.80 g/mol. Metoclopramide belongs to the aminophenyl ethers, a subclass of phenol ethers within the organic compounds. It has been recorded in 19 different sources, including healthcare, pharmaceuticals & veterinary products (Propulsives), food, food processing & cookware (Food Preservation, Preparation Of Vinegar), household cleaning & consumer products (Cigar Cigarettes, Non Electric Simulated Smoking Devices, Other Smoking Requisites, Perfumes Within Detergents And Soaps, Soap Detergents, and 2 more), and electrical & electronic equipment (Conductors Or Conductive Bodies Characterised By The Conductive Materials, Electric Hearing Aids, Electrically Stimulated Smoking Devices, Electrodes, Hybrid Capacitors, and 4 more). Recorded exposure routes for the compound include oral, nasal, intravenous, and intramuscular administration. The compound interacts with four recorded protein targets, acting as an agonist/antagonist of the D(2) dopamine receptor (DRD2), 5-hydroxytryptamine receptor 4 (HTR4), 5-hydroxytryptamine receptor 3A (HTR3A), and Muscarinic acetylcholine receptor M1 (CHRM1). In terms of health effects, metoclopramide has a therapeutic effect on nausea (PMC11340200).