Dibucaine (CED0006771)

Dibucaine is an organic compound with the formula C20H29N3O2 and an average molecular weight of 343.46 g/mol. Dibucaine belongs to the quinolones and derivatives, a subclass of quinolines and derivatives within the organic compounds. The compound is found in or released from 19 recorded sources across several categories. Within healthcare, pharmaceuticals, and veterinary products, it is associated with anesthetics, local anesthetics, antipruritics, otologicals, and vasoprotectives. It is also found in electrical and electronic equipment, including electric hearing aids, antennas, video games, electrically stimulated smoking devices, and conductors or conductive bodies characterised by the conductive materials. In the category of household cleaning and consumer products, it appears in perfumes within detergents and soaps, cigar cigarettes, non electric simulated smoking devices, pipe accessories, and other smoking requisites. Additionally, it is recorded in food, food processing, and cookware, specifically in food preservation and the preparation of vinegar. Recorded exposure routes for dibucaine include buccal, cutaneous, dental, rectal, and topical. At the molecular level, dibucaine interacts with five recorded protein targets. It acts as an inhibitor of sodium channel protein type 5 subunit alpha (SCN5A) and sodium channel protein type 10 subunit alpha (SCN10A). It also targets calmodulin-1 (CALM1), calmodulin-2 (CALM2), and one other protein.