Bufexamac (CED0014736)

Bufexamac is an organic compound with the chemical formula C12H17NO3 and an average molecular weight of 223.27 g/mol. Bufexamac belongs to the phenylacetamides, a subclass of benzene and substituted derivatives within the organic compounds. This compound is associated with 11 recorded sources. Within the category of healthcare, pharmaceuticals, and veterinary products, it is found in antiinflammatory and antirheumatic products as well as topical products for joint and muscular pain. It is also released from household cleaning and consumer products, specifically non electric simulated smoking devices. Additionally, it is found in electrical and electronic equipment, including amplifiers, discharge lamps, electric switches, electrodes, and electrically stimulated smoking devices, among three other sources. The recorded route of exposure for this substance is topical. At a molecular level, bufexamac interacts with four recorded protein targets. It acts as an inhibitor of Prostaglandin G/H synthase 1 (PTGS1) and Prostaglandin G/H synthase 2 (PTGS2). Furthermore, it targets the proteins Protein deacetylase HDAC6 and Polyamine deacetylase HDAC10.