Hydrocortisone 17-butyrate (CED0017226)

Hydrocortisone 17-butyrate belongs to the hydroxysteroids, a subclass of steroids and steroid derivatives within the organic compounds. This compound, which falls under the superclass of lipids and lipid-like molecules, has the chemical formula C25H36O6 and an average molecular weight of 432.56 g/mol. The substance is found in or released from five recorded sources, including pharmaceuticals & veterinary products such as corticosteroids and combinations with antiseptics, electrical & electronic equipment including fixed capacitors and their manufacture and electrically stimulated smoking devices, and household cleaning & consumer products specifically other smoking requisites. Recorded exposure routes for this compound are cutaneous and topical. Hydrocortisone 17-butyrate interacts with four recorded protein targets. It acts as an agonist or inhibitor of Annexin A1 (ANXA1) and the glucocorticoid receptor (NR3C1). Additionally, it targets 11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2) and 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1).