Uridine (CED0001058)

Record Information
Version1.0
Creation Date2016-05-25 18:10:06 UTC
Update Date2026-05-14 17:46:00 UTC
Accession NumberCHEM021689
Identification
Common NameUridine
ClassSmall Molecule
Description
Uridine belongs to the pyrimidine nucleosides, a class of nucleosides, nucleotides, and analogues within the organic compounds. It has the chemical formula C9H12N2O6 and an average molecular weight of 244.20 g/mol. Biologically, uridine acts as an agonist (PMC12349724) and an antioxidant (PMC13072972). It has a therapeutic effect on inflammation (PMC6348798). The compound interacts with three recorded protein targets: Thymidine phosphorylase (TYMP), the Nucleoside-specific channel-forming protein tsx, and it serves as an inhibitor of the U6 snRNA-associated Sm-like protein LSm6 (LSM6). Industrially, uridine is utilized as a humectant as well as a softener and conditioner. It is found in or released from 16 recorded sources. These include household cleaning and consumer products such as soap detergents, tobacco smoke filters, perfumes within detergents and soaps, and cigar cigarettes. It is also associated with electrical and electronic equipment, specifically X ray tubes, electrodes, antennas, television systems, and conductors or conductive bodies characterised by the conductive materials. Furthermore, uridine is found in food, food processing and cookware, including the preparation of malt, preparation of vinegar, preparation of wine or sparkling wine, fermentation processes for beer, food preservation, and two additional sources.
Contaminant TypeNot Available
Chemical Structure
Synonyms
ValueSource
1-beta-D-Ribofuranosylpyrimidine-2,4(1H,3H)-dioneChEBI
1-beta-D-RibofuranosyluracilChEBI
beta-UridineChEBI
uChEBI
UrdChEBI
UridinChEBI
1-b-D-Ribofuranosylpyrimidine-2,4(1H,3H)-dioneGenerator
1-Β-D-ribofuranosylpyrimidine-2,4(1H,3H)-dioneGenerator
1-b-D-RibofuranosyluracilGenerator
1-Β-D-ribofuranosyluracilGenerator
b-UridineGenerator
Β-uridineGenerator
1-b-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedioneHMDB
1-beta-delta-Ribofuranosyl-2,4(1H,3H)-pyrimidinedioneHMDB
1-beta-delta-RibofuranosyluracilHMDB
b-D-Ribofuranoside 2,4(1H,3H)-pyrimidinedione-1HMDB
beta-delta-Ribofuranoside 2,4(1H,3H)-pyrimidinedione-1HMDB
Allo uridineHMDB
Allo-uridineHMDB
AllouridineHMDB
Chemical FormulaC9H12N2O6
Average Molecular Mass244.201 g/mol
Monoisotopic Mass244.070 g/mol
CAS Registry Number58-96-8
IUPAC Name1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
Traditional Nameuridine
SMILESOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O
InChI IdentifierInChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChI KeyDRTQHJPVMGBUCF-XVFCMESISA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as pyrimidine nucleosides. Pyrimidine nucleosides are compounds comprising a pyrimidine base attached to a ribosyl or deoxyribosyl moiety.
KingdomOrganic compounds
Super ClassNucleosides, nucleotides, and analogues
ClassPyrimidine nucleosides
Sub ClassNot Available
Direct ParentPyrimidine nucleosides
Alternative Parents
Substituents
  • Pyrimidine nucleoside
  • Glycosyl compound
  • N-glycosyl compound
  • Pentose monosaccharide
  • Pyrimidone
  • Hydropyrimidine
  • Monosaccharide
  • Pyrimidine
  • Vinylogous amide
  • Tetrahydrofuran
  • Heteroaromatic compound
  • Urea
  • Secondary alcohol
  • Lactam
  • Organoheterocyclic compound
  • Oxacycle
  • Azacycle
  • Hydrocarbon derivative
  • Organopnictogen compound
  • Organooxygen compound
  • Organonitrogen compound
  • Primary alcohol
  • Alcohol
  • Organic oxygen compound
  • Organic oxide
  • Organic nitrogen compound
  • Aromatic heteromonocyclic compound
Molecular FrameworkAromatic heteromonocyclic compounds
External Descriptors
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological Roles
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted Properties
PropertyValueSource
Water Solubility135 g/LALOGPS
logP-1.8ALOGPS
logP-2.4ChemAxon
logS-0.26ALOGPS
pKa (Strongest Acidic)9.7ChemAxon
pKa (Strongest Basic)-3ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count4ChemAxon
Polar Surface Area119.33 ŲChemAxon
Rotatable Bond Count2ChemAxon
Refractivity52.57 m³·mol⁻¹ChemAxon
Polarizability21.81 ųChemAxon
Number of Rings2ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
GC-MSGC-MS Spectrumsplash10-00kb-1970000000-d1bfa838a4e9fa77c862Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-00kb-1960000000-a8283468b762a8520102Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-014i-1950000000-70fdf4785544d0968f70Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-00di-9520000000-591c0bcf8f956d710367Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-066s-2970000000-36fbef6f6b10c2895df4Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-014i-1890000000-dd0569d4351a64c566c9Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-00kb-1970000000-d1bfa838a4e9fa77c862Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-00kb-1960000000-a8283468b762a8520102Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-014i-1950000000-70fdf4785544d0968f70Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-00di-9520000000-591c0bcf8f956d710367Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-066s-2970000000-36fbef6f6b10c2895df4Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-014i-1890000000-dd0569d4351a64c566c9Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-014j-1940000000-8b7a5ce66afa9b9bf939Not AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-00kb-1950000000-00519445de22f955367dNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS Spectrumsplash10-056u-9530000000-e83d5f042dbda82911cfNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS Spectrumsplash10-0g30-5935200000-88c9a24e13b0f41cbc83Not AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0900000000-7010b37007f5c3d9ce1fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-3900000000-b4639c8c89eac6158da6Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-022a-9200000000-f8472930d09b32f54790Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0291000000-aebaa77a411473acb859Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014j-9000000000-205562662b564ebdca28Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0900000000-776595fd1c19f6ec51cdNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-0900000000-10358e53c56bcb50ed4cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0002-0971000000-f989283d2dec564a3af0Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00kf-9000000000-c11e7bfdec0b5c7bf450Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-9000000000-104e62fbffc4110779efNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0900000000-eaf6ff9ac3971d6f045fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-052f-0697120000-c9fd5b8d641165d84e92Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-9000000000-995de18be458c48a8d2dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0590000000-4d1d6aba25697dd11da8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uki-0190000000-3aea11527d0520158d77Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-004l-0291010000-c8f22405e9290fccc011Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0490000000-1a2f990a874bb1868249Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-0090000000-c8efbe58f0df63698b2cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-0090000000-7495d9b948a8e3b7b83bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03dj-3960000000-3466ccfdf88139ddf140Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-3900000000-0d08e4a7d4b8aacee6e6Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-4900000000-d942ee27b3ca1d6ef94dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-9700000000-594c7bb6dc6de848ff11Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-022d-9100000000-2826c4eb794745ec3148Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0910000000-617b4ec6cf749942c0cdNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-5900000000-69944d9ce81849ec71c6Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ikc-2970000000-089539e61aec5eeed279Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0w2c-0970000000-e6a764f50c4a9c460396Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0690000000-357cb54739a10dfcbd65Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-9000000000-995de18be458c48a8d2dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0590000000-4d1d6aba25697dd11da8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0uki-0190000000-3aea11527d0520158d77Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0490000000-1a2f990a874bb1868249Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-0090000000-d9e34a80f1a6b4481494Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-0090000000-7495d9b948a8e3b7b83bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0ikc-2970000000-089539e61aec5eeed279Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03dj-3960000000-3466ccfdf88139ddf140Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-3900000000-305d7746674473d0fdf5Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-4900000000-10340fb76655d3f993a0Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-9700000000-1ddefb0b972a63b62682Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-022d-9100000000-2826c4eb794745ec3148Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0910000000-566ed331b13b3c9cf8e9Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014j-9000000000-205562662b564ebdca28Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0900000000-776595fd1c19f6ec51cdNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-0900000000-10358e53c56bcb50ed4cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00kf-9000000000-c11e7bfdec0b5c7bf450Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000i-9000000000-aa4ba481865df59b0da8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0900000000-eaf6ff9ac3971d6f045fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-9000000000-22adf05cd6250b522846Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0900000000-eb036ac6f204eb98ee77Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-5900000000-efb272bb20fe5e4cd0f9Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0900000000-dd2da1e1be68e34a9e0dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-4900000000-db2eab0e5836a4c0e10fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0gvo-3960000000-63c0257f68728eff5fd3Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03dl-9700000000-62e2e6548cdb1897e0bbNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-9100000000-9c7ae265690df0b7d97eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-2900000000-8f5067de80235cee3b58Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0900000000-447b9a0dd2cc7c4ebe24Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03ka-9400000000-a0ce5f8853cefbeb0fc7Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-3900000000-9727d15c84c87077df0bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0w2c-0970000000-15e60929e51e5f390b23Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-1900000000-3b0d4b7175bb18bbdc69Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-6900000000-ff43ab044d182cb21fddNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00dm-9100000000-986f50ea4db77a6ef320Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-2900000000-f7304b07fcd8fc7ee4f2Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-9100000000-1cf79cc1fd6c74f9b9c3Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00lr-9000000000-6c1891b4925cdd101116Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0900000000-849686292a8a4b3eb17dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-2900000000-0cf850cefdb5818f7ba4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0910000000-e4f57832c46599d59f22Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-1900000000-e7e20c4f6258dbc52595Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-1910000000-534db9c72bfa7c2f93e1Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00lr-9000000000-ef6c2c28637a6a0c6776Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0900000000-8b3dd4dc42c72ba6eadeNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-8900000000-ed7a023d0c181379c5beNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-0090000000-b1643e047ad84ace113cNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-000x-9200000000-25d36704493de819e6fbNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-9000000000-1f2658aecb044b42e407Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0930000000-cc45d2ac554d7cb7f457Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-022a-9200000000-a45495ff6a38d19a25cfNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-2900000000-ab5c8dd595d9990e1e11Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-1900000000-8cd384768a6364797503Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-9300000000-c0383a006476ea195ab8Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0900000000-2df9db5e243b232a2c7fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-03di-0900000000-c185d886669df5ea6eabNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-022a-9300000000-d8e1a211d83dc7056890Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-9500000000-53963aa14e89c415355bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-9100000000-90d99475b0bce85c6d2cNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03di-1920000000-5936394292759ebd1ed4Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03di-6900000000-6bb6b7978ce5d55f66b2Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03dj-9500000000-e70fb8201ceb91949c3fNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03dl-2950000000-708783a8123364addf71Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0006-9730000000-4dedc4154cb6569dd0c6Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0006-9100000000-943a9331d4bd8bcd71edNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03xr-1900000000-bad94607edef480a099eNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03di-3910000000-c6e9c4ac15a6397215efNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03dl-9500000000-5cd22904b9c6831c9682Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-01r6-0790000000-793b6893ddaa6c23c4dbNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-03dl-4920000000-889926e69e8107825a0aNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0006-9200000000-3ce9e2a3e56cb6abccf3Not AvailableView Spectrum
MSMS Spectrumsplash10-08mi-9400000000-bafe048989f1a5c86d2dNot AvailableView Spectrum
1D NMR13C NMR Spectrum (1D, D2O, predicted)Not AvailableNot AvailableView Spectrum
1D NMR1H NMR Spectrum (1D, D2O, predicted)Not AvailableNot AvailableView Spectrum
1D NMR1H NMR Spectrum (1D, H2O, experimental)Not AvailableNot AvailableView Spectrum
1D NMR13C NMR Spectrum (1D, H2O, experimental)Not AvailableNot AvailableView Spectrum
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity Values
Toxicity ValueUnitValue RangeOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalReference
3377.0Log mg/kg[1900:6000]RatLD50oralpredictedNot Available
Health Effects
Health EffectRelationshipDirectionReference
inflammationhas_therapeutic_effect_onNot AvailablePMC6348798
hepatic fibrosishas_therapeutic_effect_onNot AvailablePMC12349724
Exposure Sources
Source IDSourceSectorReference
10InsecticidesAgriculture & land managementNot Available
506AntennasElectrical & Electronic EquipmentNot Available
511Conductors Or Conductive Bodies Characterised By The Conductive MaterialsElectrical & Electronic EquipmentNot Available
519ElectrodesElectrical & Electronic EquipmentNot Available
537Television SystemsElectrical & Electronic EquipmentNot Available
540X Ray TubesElectrical & Electronic EquipmentNot Available
544Fermentation Processes For BeerFood, food processing & cookwareNot Available
545Food PreservationFood, food processing & cookwareNot Available
547Preparation Of MaltFood, food processing & cookwareNot Available
548Preparation Of VinegarFood, food processing & cookwareNot Available
549Preparation Of Wine Or Sparkling WineFood, food processing & cookwareNot Available
550Preparation Of WortFood, food processing & cookwareNot Available
551Processing FishFood, food processing & cookwareNot Available
556Cigar CigarettesHousehold cleaning & consumer productsNot Available
561Perfumes Within Detergents And SoapsHousehold cleaning & consumer productsNot Available
563Soap DetergentsHousehold cleaning & consumer productsNot Available
569Tobacco Smoke FiltersHousehold cleaning & consumer productsNot Available
580Manufacture Preparation Of Tobacco ProductsIndustrial manufacturing & chemical processingNot Available
596AcaricidesAgriculture & land managementNot Available
600Herbicides And AlgicidesAgriculture & land managementNot Available
603NematocidesAgriculture & land managementNot Available
606Plant Growth RegulatorsAgriculture & land managementNot Available
609AftershavePersonal care & cosmeticsNot Available
610Aftersun ProductsPersonal care & cosmeticsNot Available
611Anti Perspirants Or Body DeoderantsPersonal care & cosmeticsNot Available
614Essential Oils Or PerfumesPersonal care & cosmeticsNot Available
615Eye Makeup ProductsPersonal care & cosmeticsNot Available
616Face Mask CosmeticsPersonal care & cosmeticsNot Available
617Lip Care ProductsPersonal care & cosmeticsNot Available
618Lip Makeup ProductsPersonal care & cosmeticsNot Available
632ApparelTextiles, leather & furnishingsNot Available
634BucklesTextiles, leather & furnishingsNot Available
642FootwearTextiles, leather & furnishingsNot Available
Pathways
10 pathways
Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureRibonuclease pancreaticP61823Bos taurusPredicted (SEA)0.0778492
Click to view 3D structureP2Y purinoceptor 2P41231HumansPredicted (SEA)3.34752
Click to view 3D structureP2Y purinoceptor 6Q15077HumansPredicted (SEA)2.72472
Cytidine deaminase structureClick to view 3D structureCytidine deaminaseP32320HumansPredicted (SEA)0.0778492
Click to view 3D structureP2Y purinoceptor 14Q15391HumansPredicted (SEA)2.33548
Solute carrier family 28 member 3 structureClick to view 3D structureSolute carrier family 28 member 3Q9HAS3HumansPredicted (SEA)0.0778492
Click to view 3D structureP2Y purinoceptor 4P51582HumansPredicted (SEA)3.58106
Click to view 3D structureP2Y purinoceptor 2P41232Rattus norvegicusPredicted (SEA)2.10193
Click to view 3D structureP2Y purinoceptor 6Q63371Rattus norvegicusPredicted (SEA)3.19182
Click to view 3D structureSodium/nucleoside cotransporter 1O00337HumansPredicted (SEA)0.155698
Click to view 3D structureCytidine deaminaseP56389Mus musculusPredicted (SEA)0.0778492
Click to view 3D structureThymidine kinaseP09250HHV-3Predicted (SEA)0.233548
Click to view 3D structure5'-nucleotidaseP21588Rattus norvegicusPredicted (SEA)5.2159
Click to view 3D structureAdenosine kinaseP9WID4Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)Predicted (SEA)0.778492
Adenosine kinase structureClick to view 3D structureAdenosine kinaseP55263HumansPredicted (SEA)6.07224
Click to view 3D structureAdenosine deaminaseP56658Bos taurusPredicted (SEA)5.99439
Click to view 3D structureOrotidine phosphate decarboxylaseQ8T6J6Plasmodium falciparumPredicted (SEA)2.33548
Click to view 3D structureAdenosine receptor A1P25099Rattus norvegicusPredicted (SEA)63.2136
Adenosine receptor A1 structureClick to view 3D structureAdenosine receptor A1P30542HumansPredicted (SEA)62.1237
Ribonuclease pancreatic structureClick to view 3D structureRibonuclease pancreaticP07998HumansPredicted (SEA)3.81461
Non-secretory ribonuclease structureClick to view 3D structureNon-secretory ribonucleaseP10153HumansPredicted (SEA)3.81461
Click to view 3D structureAdenosine receptor A2aP30543Rattus norvegicusPredicted (SEA)63.2136
P2Y purinoceptor 1 structureClick to view 3D structureP2Y purinoceptor 1P47900HumansPredicted (SEA)24.0554
Click to view 3D structurePhospho-N-acetylmuramoyl-pentapeptide-transferaseE2QF15Escherichia coliPredicted (SEA)0.622794
Click to view 3D structureP2Y purinoceptor 14O35881Rattus norvegicusPredicted (SEA)1.40129
Concentrations
Not Available
External Links
DrugBank IDDB02745
HMDB IDHMDB0000296
FooDB IDFDB007411
Phenol Explorer IDNot Available
KNApSAcK IDC00019674
BiGG ID34541
BioCyc IDURIDINE
METLIN ID90
PDB IDNot Available
Wikipedia LinkUridine
Chemspider ID5807
ChEBI ID16704
PubChem Compound ID6029
Kegg Compound IDC00299
YMDB IDYMDB00127
ECMDB IDECMDB00296
References
Synthesis ReferenceNot Available
MSDSNot Available
General References
1. https://www.ncbi.nlm.nih.gov/pubmed/?term=12084455
2. https://www.ncbi.nlm.nih.gov/pubmed/?term=15621516
3. https://www.ncbi.nlm.nih.gov/pubmed/?term=16839635
4. https://www.ncbi.nlm.nih.gov/pubmed/?term=17190852
5. https://www.ncbi.nlm.nih.gov/pubmed/?term=22392515
6. https://www.ncbi.nlm.nih.gov/pubmed/?term=22770225
7. Doi, Muneharu; Asahi, Satoru; Izawa, Motoo. Fermentative production of uridine and cytidine. Baiosaiensu to Indasutori (1993), 51(12), 972-6.
8. Schlimme E, Raezke KP, Ott FG: Ribonucleosides as minor milk constituents. Z Ernahrungswiss. 1991 Jun;30(2):138-52.
9. Tiemeyer W, Stohrer M, Giesecke D: Metabolites of nucleic acids in bovine milk. J Dairy Sci. 1984 Apr;67(4):723-8. doi: 10.3168/jds.S0022-0302(84)81361-2.
10. Schlimme E, Martin D, Meisel H: Nucleosides and nucleotides: natural bioactive substances in milk and colostrum. Br J Nutr. 2000 Nov;84 Suppl 1:S59-68.
11. Mung D, Li L: Development of Chemical Isotope Labeling LC-MS for Milk Metabolomics: Comprehensive and Quantitative Profiling of the Amine/Phenol Submetabolome. Anal Chem. 2017 Apr 18;89(8):4435-4443. doi: 10.1021/acs.analchem.6b03737. Epub 2017 Mar 28.
12. O'Callaghan TF, Vazquez-Fresno R, Serra-Cayuela A, Dong E, Mandal R, Hennessy D, McAuliffe S, Dillon P, Wishart DS, Stanton C, Ross RP: Pasture Feeding Changes the Bovine Rumen and Milk Metabolome. Metabolites. 2018 Apr 6;8(2). pii: metabo8020027. doi: 10.3390/metabo8020027.
13. Mung D, Li L: Applying quantitative metabolomics based on chemical isotope labeling LC-MS for detecting potential milk adulterant in human milk. Anal Chim Acta. 2018 Feb 25;1001:78-85. doi: 10.1016/j.aca.2017.11.019. Epub 2017 Nov 14.
14. Kurt J. Boudonck, Matthew W. Mitchell, Jacob Wulff and John A. Ryals. Characterization of the biochemical variability of bovine milk using metabolomics. Metabolomics (2009) 5:375?386
15. A. Foroutan et al. The Chemical Composition of Commercial Cow's Milk (in preparation)
16. Doi, Muneharu; Asahi, Satoru; Izawa, Motoo. Fermentative production of uridine and cytidine. Baiosaiensu to Indasutori (1993), 51(12), 972-6.
17. Lee SH, Jung BH, Kim SY, Chung BC: A rapid and sensitive method for quantitation of nucleosides in human urine using liquid chromatography/mass spectrometry with direct urine injection. Rapid Commun Mass Spectrom. 2004;18(9):973-7.
18. Eells JT, Spector R: Purine and pyrimidine base and nucleoside concentrations in human cerebrospinal fluid and plasma. Neurochem Res. 1983 Nov;8(11):1451-7.