Phenylephrine (CED0001601)

Record Information
Version1.0
Creation Date2016-05-25 18:12:38 UTC
Update Date2026-05-14 16:37:17 UTC
Accession NumberCHEM021794
Identification
Common NamePhenylephrine
ClassSmall Molecule
Description
Phenylephrine is an organic compound with the formula C9H13NO2 and an average molecular weight of 167.21 g/mol. Phenylephrine belongs to the 1-hydroxy-4-unsubstituted benzenoids, a subclass of phenols within the organic compounds. It is recorded as an agonist for the D(2) dopamine receptor (DRD2) as well as the Alpha-1A, Alpha-1B, and Alpha-1D adrenergic receptors (ADRA1A, ADRA1B, and ADRA1D). The compound is found in or released from 24 recorded sources across several categories. Within healthcare, pharmaceuticals, and veterinary products, it is used in nasal preparations, decongestants and antiallergics, mydriatics and cycloplegics, vasoprotectives, and cardiac stimulants excluding cardiac glycosides. In the context of food and food processing, it is associated with food preservation, the preparation of vinegar, and fermentation processes for beer. It is also found in drinking water, ceilings, and various household cleaning and consumer products, including perfumes within detergents and soaps, tobacco product cases, cigar cigarettes, non electric simulated smoking devices, and other smoking requisites. Additionally, it is found in electrical and electronic equipment, such as electrodes, electrically stimulated smoking devices, electric hearing aids, communication cables or conductors, and conductors or conductive bodies characterised by the conductive materials. Recorded exposure routes for phenylephrine include oral, nasal, ophthalmic, intraocular, auricular, intravenous, intramuscular, subcutaneous, rectal, respiratory, topical, and irrigation.
Contaminant TypeNot Available
Chemical Structure
Synonyms
ValueSource
(-)-m-Hydroxy-alpha-(methylaminomethyl)benzyl alcoholChEBI
FenilefrinaChEBI
L-(3-Hydroxyphenyl)-N-methylethanolamineChEBI
PhenylephrinumChEBI
R(-)-PhenylephrineChEBI
Phenylephrine minimsKegg
(-)-m-Hydroxy-a-(methylaminomethyl)benzyl alcoholGenerator
(-)-m-Hydroxy-α-(methylaminomethyl)benzyl alcoholGenerator
AdrianolHMDB
Ak-dilateHMDB
Ak-nefrinHMDB
Alcon efrinHMDB
Alconefrin nasal drops 12HMDB
Alconefrin nasal drops 25HMDB
Alconefrin nasal drops 50HMDB
Alconefrin nasal spray 25HMDB
BiomydrinHMDB
DilatairHMDB
DionephrineHMDB
DoktorsHMDB
DurationHMDB
I-phrineHMDB
IsophrimHMDB
IsophrinHMDB
Isopto frinHMDB
m-MethylaminoethanolphenolHMDB
m-OxedrineHMDB
m-SympatholHMDB
m-SympatolHMDB
m-SynephrineHMDB
MesatonHMDB
MesatoneHMDB
MesatonumHMDB
MetaoxedrinHMDB
MetaoxedrineHMDB
MetaoxedrinumHMDB
MetasympatolHMDB
MetasynephrineHMDB
MezatonHMDB
Minims phenylephrineHMDB
MydfrinHMDB
Neo-synephrineHMDB
Neo-synephrine nasal dropsHMDB
Neo-synephrine nasal jellyHMDB
Neo-synephrine nasal sprayHMDB
Neo-synephrine pediatric nasal dropsHMDB
NeofrinHMDB
NeophrynHMDB
NeosynephrineHMDB
NostrilHMDB
Nostril spray pumpHMDB
Nostril spray pump mildHMDB
Ocu-phrin sterile eye dropsHMDB
Ocu-phrin sterile ophthalmic solutionHMDB
OcugestrinHMDB
PhenopticHMDB
PrefrinHMDB
Prefrin liquifilmHMDB
Pyracort DHMDB
R(-)-MezatonHMDB
Relief eye drops for red eyesHMDB
RhinallHMDB
SpersaphrineHMDB
Vicks sinexHMDB
VisadronHMDB
Neo synephrineHMDB
Phenylephrine tannateHMDB
Tannate, phenylephrineHMDB
(R)-3-Hydroxy-alpha-((methylamino)methyl)benzenemethanolHMDB
Phenylephrine hydrochlorideHMDB
Chemical FormulaC9H13NO2
Average Molecular Mass167.205 g/mol
Monoisotopic Mass167.095 g/mol
CAS Registry Number59-42-7
IUPAC Name3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol
Traditional Namephenylephrine
SMILESCNC[C@H](O)C1=CC(O)=CC=C1
InChI IdentifierInChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/t9-/m0/s1
InChI KeySONNWYBIRXJNDC-VIFPVBQESA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as 1-hydroxy-4-unsubstituted benzenoids. These are phenols that are unsubstituted at the 4-position.
KingdomOrganic compounds
Super ClassBenzenoids
ClassPhenols
Sub Class1-hydroxy-4-unsubstituted benzenoids
Direct Parent1-hydroxy-4-unsubstituted benzenoids
Alternative Parents
Substituents
  • 1-hydroxy-4-unsubstituted benzenoid
  • 1-hydroxy-2-unsubstituted benzenoid
  • Aralkylamine
  • Monocyclic benzene moiety
  • 1,2-aminoalcohol
  • Secondary alcohol
  • Secondary aliphatic amine
  • Secondary amine
  • Alcohol
  • Organopnictogen compound
  • Organooxygen compound
  • Organonitrogen compound
  • Organic nitrogen compound
  • Organic oxygen compound
  • Amine
  • Aromatic alcohol
  • Hydrocarbon derivative
  • Aromatic homomonocyclic compound
Molecular FrameworkAromatic homomonocyclic compounds
External Descriptors
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted Properties
PropertyValueSource
Water Solubility22 g/LALOGPS
logP-0.69ALOGPS
logP-0.07ChemAxon
logS-0.88ALOGPS
pKa (Strongest Acidic)9.07ChemAxon
pKa (Strongest Basic)9.69ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area52.49 ŲChemAxon
Rotatable Bond Count3ChemAxon
Refractivity47.25 m³·mol⁻¹ChemAxon
Polarizability18.2 ųChemAxon
Number of Rings1ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
GC-MSGC-MS Spectrumsplash10-014i-0900000000-b11a2a880d1683fa6caeNot AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-01b9-6900000000-bbdd210a846be116dbcdNot AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-014i-0900000000-b11a2a880d1683fa6caeNot AvailableView Spectrum
GC-MSGC-MS Spectrumsplash10-01b9-6900000000-bbdd210a846be116dbcdNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS Spectrumsplash10-0006-9200000000-3ea7ffd258ffba5a376aNot AvailableView Spectrum
Predicted GC-MSPredicted GC-MS Spectrumsplash10-014i-4920000000-54a2b2a88914c83610f2Not AvailableView Spectrum
Predicted GC-MSPredicted GC-MS SpectrumNot AvailableNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0900000000-d95a741ffcfe3f7bb7e9Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0006-9800000000-7695881b36499169fb71Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-054o-9200000000-888fce606d860cd39be2Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0900000000-edfcbc18ccdb6872b791Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0900000000-15132688bbc7ac0be42fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-2900000000-34ccc7192518d4c14210Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-3900000000-e619f4210f81c11f61beNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00dl-6900000000-3178337a019ac9bf313dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0gb9-0900000000-e738818606836c1d6d1aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0900000000-36b72327f64f1355a502Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-052o-4900000000-935a9659fe39602b138dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-052f-9800000000-7d83555b537d6fec673bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-054o-9400000000-5ef2f6d1da57087e6ac7Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0900000000-4a910a2109ba191b96e7Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0900000000-edfcbc18ccdb6872b791Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-0900000000-15132688bbc7ac0be42fNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-2900000000-34ccc7192518d4c14210Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00di-3900000000-e8a5a4f1aae0796866a7Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-00dl-6900000000-3178337a019ac9bf313dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0900000000-c0d824f22be752d523b4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0900000000-4fb67ae2344d097c3abbNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0900000000-113e95fddc78edd9df82Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zg3-2900000000-a52b0d450061f2762c71Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-052o-4900000000-1919f188c550710ea860Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-052f-6900000000-93a02b958e60eadd5bfbNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0gb9-0900000000-e738818606836c1d6d1aNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0900000000-36b72327f64f1355a502Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-052o-4900000000-5c34ff7c978e4b607f00Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-052f-9800000000-036a3eb2e3b11f203fd4Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-054o-9400000000-284961abd6764baa0d1dNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-014i-0900000000-4a910a2109ba191b96e7Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0900000000-737e97e0756ab00c7cafNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0900000000-6b6d494fa9b3fbbfc5b9Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-052f-6900000000-cc83bbe5e57a5045146bNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-052o-4900000000-d2742e2a663aca0a523eNot AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0udi-0900000000-52d23c8accc0c346d880Not AvailableView Spectrum
LC-MS/MSLC-MS/MS Spectrumsplash10-0zg3-2900000000-fd63c9410b1eac375837Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0uxr-0900000000-8c4893aa69ea6a1ceecbNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0uxr-0900000000-4406afb22d76646e2ef8Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-01c3-7900000000-56a2a2741d2166bf31bcNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-014i-0900000000-0cf5a5fa80f87facb9adNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-014j-2900000000-687762e0d4bf3efbffecNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0006-9400000000-140e96de62b4341791d9Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0uxr-0900000000-a42f82c8742e0dd7aa4aNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-0aor-0900000000-ab7af27655c243c56a82Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-066r-9700000000-a22893f3d9a454184339Not AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-014i-0900000000-875f22d51d757a79e7ddNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-01bc-2900000000-656cd2188447f7cfa73bNot AvailableView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrumsplash10-00kf-9600000000-ec7fed4aec16b9e6787cNot AvailableView Spectrum
1D NMR13C NMR Spectrum (1D, D2O, predicted)Not AvailableNot AvailableView Spectrum
1D NMR1H NMR Spectrum (1D, D2O, predicted)Not AvailableNot AvailableView Spectrum
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity Values
Toxicity ValueUnitValue RangeOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalReference
259.0Log mg/kg[150:460]RatLD50oralpredictedNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
10InsecticidesAgriculture & land managementNot Available
115Drinking waterDrinking water & water supplyNot Available
233BrushesPersonal care & cosmeticsNot Available
286Cardiac stimulants excl. cardiac glycosidesHealthcare, pharmaceuticals & veterinary productsNot Available
292VasoprotectivesHealthcare, pharmaceuticals & veterinary productsNot Available
389Nasal preparationsHealthcare, pharmaceuticals & veterinary productsNot Available
399Mydriatics and cycloplegicsHealthcare, pharmaceuticals & veterinary productsNot Available
400Decongestants and antiallergicsHealthcare, pharmaceuticals & veterinary productsNot Available
495CeilingsBuilding & ConstructionNot Available
510Communication Cables Or ConductorsElectrical & Electronic EquipmentNot Available
511Conductors Or Conductive Bodies Characterised By The Conductive MaterialsElectrical & Electronic EquipmentNot Available
516Electric Hearing AidsElectrical & Electronic EquipmentNot Available
518Electrically Stimulated Smoking DevicesElectrical & Electronic EquipmentNot Available
519ElectrodesElectrical & Electronic EquipmentNot Available
524Hybrid CapacitorsElectrical & Electronic EquipmentNot Available
537Television SystemsElectrical & Electronic EquipmentNot Available
540X Ray TubesElectrical & Electronic EquipmentNot Available
544Fermentation Processes For BeerFood, food processing & cookwareNot Available
545Food PreservationFood, food processing & cookwareNot Available
548Preparation Of VinegarFood, food processing & cookwareNot Available
556Cigar CigarettesHousehold cleaning & consumer productsNot Available
559Non Electric Simulated Smoking DevicesHousehold cleaning & consumer productsNot Available
560Other Smoking RequisitesHousehold cleaning & consumer productsNot Available
561Perfumes Within Detergents And SoapsHousehold cleaning & consumer productsNot Available
567Tobacco Product CasesHousehold cleaning & consumer productsNot Available
569Tobacco Smoke FiltersHousehold cleaning & consumer productsNot Available
579Manufacture Of Iron Or SteelIndustrial manufacturing & chemical processingNot Available
580Manufacture Preparation Of Tobacco ProductsIndustrial manufacturing & chemical processingNot Available
596AcaricidesAgriculture & land managementNot Available
600Herbicides And AlgicidesAgriculture & land managementNot Available
605Pest RepellantsAgriculture & land managementNot Available
609AftershavePersonal care & cosmeticsNot Available
610Aftersun ProductsPersonal care & cosmeticsNot Available
611Anti Perspirants Or Body DeoderantsPersonal care & cosmeticsNot Available
612Body Washing Or Cleaning ImplementsPersonal care & cosmeticsNot Available
613DepilatoriesPersonal care & cosmeticsNot Available
614Essential Oils Or PerfumesPersonal care & cosmeticsNot Available
615Eye Makeup ProductsPersonal care & cosmeticsNot Available
616Face Mask CosmeticsPersonal care & cosmeticsNot Available
617Lip Care ProductsPersonal care & cosmeticsNot Available
618Lip Makeup ProductsPersonal care & cosmeticsNot Available
632ApparelTextiles, leather & furnishingsNot Available
642FootwearTextiles, leather & furnishingsNot Available
650Purses Luggage Hand BagsTextiles, leather & furnishingsNot Available
657Surface Finishing Of LeatherTextiles, leather & furnishingsNot Available
662Yarns Or ThreadsTextiles, leather & furnishingsNot Available
Pathways
2 pathways
Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Alpha-1A adrenergic receptor structureClick to view 3D structureAlpha-1A adrenergic receptorP35348HumansPredicted (SEA)9.73115
Click to view 3D structureAlpha-1A adrenergic receptorP43140Rattus norvegicusPredicted (SEA)9.18621
Alpha-2A adrenergic receptor structureClick to view 3D structureAlpha-2A adrenergic receptorP08913HumansPredicted (SEA)12.3002
Alpha-2C adrenergic receptor structureClick to view 3D structureAlpha-2C adrenergic receptorP18825HumansPredicted (SEA)8.64126
Click to view 3D structureKynureninaseP70712Rattus norvegicusPredicted (SEA)0.0778492
Click to view 3D structureAlpha-1B adrenergic receptorP35368HumansPredicted (SEA)15.6477
Beta-2 adrenergic receptor structureClick to view 3D structureBeta-2 adrenergic receptorP07550HumansPredicted (SEA)8.79696
Click to view 3D structureBeta-1 adrenergic receptorB0FL73Cavia porcellusPredicted (SEA)2.95827
Click to view 3D structureBeta-2 adrenergic receptorQ8K4Z4Cavia porcellusPredicted (SEA)4.9045
Click to view 3D structureBeta-1 adrenergic receptorP18090Rattus norvegicusPredicted (SEA)2.49118
Click to view 3D structureBeta-2 adrenergic receptorP10608Rattus norvegicusPredicted (SEA)0.934191
Beta-1 adrenergic receptor structureClick to view 3D structureBeta-1 adrenergic receptorP08588HumansPredicted (SEA)11.7552
Sodium-dependent serotonin transporter structureClick to view 3D structureSodium-dependent serotonin transporterP31645HumansPredicted (SEA)62.6686
Beta-3 adrenergic receptor structureClick to view 3D structureBeta-3 adrenergic receptorP13945HumansPredicted (SEA)9.73115
Click to view 3D structureTaste receptor type 2 member 50P59544HumansPredicted (SEA)0.856341
Click to view 3D structureTaste receptor type 2 member 45P59539HumansPredicted (SEA)0.856341
Click to view 3D structureTaste receptor type 2 member 42Q7RTR8HumansPredicted (SEA)0.856341
Click to view 3D structureTaste receptor type 2 member 41P59536HumansPredicted (SEA)0.856341
Click to view 3D structureTaste receptor type 2 member 7Q9NYW3HumansPredicted (SEA)0.856341
Click to view 3D structureTaste receptor type 2 member 30P59541HumansPredicted (SEA)0.856341
Click to view 3D structureTaste receptor type 2 member 60P59551HumansPredicted (SEA)0.856341
Click to view 3D structureTaste receptor type 2 member 19P59542HumansPredicted (SEA)0.856341
Click to view 3D structureTaste receptor type 2 member 20P59543HumansPredicted (SEA)0.856341
Click to view 3D structureTaste receptor type 2 member 1Q9NYW7HumansPredicted (SEA)0.856341
Click to view 3D structureTaste receptor type 2 member 40P59535HumansPredicted (SEA)0.856341
Concentrations
Not Available
External Links
DrugBank IDDB00388
HMDB IDHMDB0002182
FooDB IDFDB022891
Phenol Explorer IDNot Available
KNApSAcK IDNot Available
BiGG IDNot Available
BioCyc IDNot Available
METLIN ID699
PDB IDNot Available
Wikipedia LinkPhenylephrine
Chemspider ID5818
ChEBI ID8093
PubChem Compound ID6041
Kegg Compound IDC07441
YMDB IDNot Available
ECMDB IDNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General References
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2. Thebault S, Zholos A, Enfissi A, Slomianny C, Dewailly E, Roudbaraki M, Parys J, Prevarskaya N: Receptor-operated Ca2+ entry mediated by TRPC3/TRPC6 proteins in rat prostate smooth muscle (PS1) cell line. J Cell Physiol. 2005 Jul;204(1):320-8.
3. Rios JD, Horikawa Y, Chen LL, Kublin CL, Hodges RR, Dartt DA, Zoukhri D: Age-dependent alterations in mouse exorbital lacrimal gland structure, innervation and secretory response. Exp Eye Res. 2005 Apr;80(4):477-91.
4. Gao YJ, Zeng ZH, Teoh K, Sharma AM, Abouzahr L, Cybulsky I, Lamy A, Semelhago L, Lee RM: Perivascular adipose tissue modulates vascular function in the human internal thoracic artery. J Thorac Cardiovasc Surg. 2005 Oct;130(4):1130-6.
5. Gonzalez-Cadavid NF, Ryndin I, Vernet D, Magee TR, Rajfer J: Presence of NMDA receptor subunits in the male lower urogenital tract. J Androl. 2000 Jul-Aug;21(4):566-78.
6. Grassi G, Dell'Oro R, Facchini A, Quarti Trevano F, Bolla GB, Mancia G: Effect of central and peripheral body fat distribution on sympathetic and baroreflex function in obese normotensives. J Hypertens. 2004 Dec;22(12):2363-9.
7. Bouchelouche K, Andersen L, Alvarez S, Nordling J, Bouchelouche P: Increased contractile response to phenylephrine in detrusor of patients with bladder outlet obstruction: effect of the alpha1A and alpha1D-adrenergic receptor antagonist tamsulosin. J Urol. 2005 Feb;173(2):657-61.
8. Boschmann M, Krupp G, Luft FC, Klaus S, Jordan J: In vivo response to alpha(1)-adrenoreceptor stimulation in human white adipose tissue. Obes Res. 2002 Jun;10(6):555-8.
9. Chueh SC, Chern JW, Choong CM, Guh JH, Teng CM: Characterization of some novel alpha 1-adrenoceptor antagonists in human hyperplastic prostate. Eur J Pharmacol. 2002 Jun 7;445(1-2):125-31.
10. Wang SY, Song Y, Xu M, Hao TP, Han QD, Zhang YY: [Redistribution of three alpha1-adrenergic receptor subtypes in the stably transfected HEK 293A cells upon agonist stimulation.]. Sheng Li Xue Bao. 2005 Aug 25;57(4):480-5.
11. Guh JH, Hsieh CH, Teng CM: Investigation of the effects of some alkaloidal alpha1-adrenoceptor antagonists on human hyperplastic prostate. Eur J Pharmacol. 1999 Jun 25;374(3):503-10.
12. Nomiya M, Yamaguchi O: A quantitative analysis of mRNA expression of alpha 1 and beta-adrenoceptor subtypes and their functional roles in human normal and obstructed bladders. J Urol. 2003 Aug;170(2 Pt 1):649-53.
13. Lam KY, Yuen AP: Cancer of the larynx in Hong Kong: a clinico-pathological study. Eur J Surg Oncol. 1996 Apr;22(2):166-70.
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