Pheniramine (CED0008326)

Pheniramine is an organic compound with the formula C16H20N2 and an average molecular weight of 240.34 g/mol. Pheniramine belongs to the pheniramines, a subclass of pyridines and derivatives within the organic compounds. This substance is categorized as an organoheterocyclic compound. The compound is found in or released from seven recorded sources. These include healthcare, pharmaceuticals, and veterinary products, specifically antihistamines and antipruritics. It is also associated with household cleaning and consumer products, such as cigar cigarettes and other smoking requisites, as well as electrical and electronic equipment, including relays and electrically stimulated smoking devices. Additionally, it is found in building and construction materials, specifically fencing. Recorded exposure routes for pheniramine include oral, ophthalmic, and nasal pathways. At the molecular level, pheniramine interacts with three recorded protein targets. It acts as an agonist or inverse agonist of the histamine H1 receptor (HRH1) and the histamine H4 receptor (HRH4), as well as the nuclear receptor subfamily 1 group I member 3 (NR1I3).