articaine (CED0005393)

Articaine is an organic compound with the chemical formula C13H20N2O3S and an average molecular weight of 284.37 g/mol. Articaine belongs to the thiophene carboxylic acids and derivatives, a subclass of thiophenes within the organic compounds. It is categorized as an organoheterocyclic compound. The compound is found in or released from four recorded sources: pharmaceuticals & veterinary products specifically as anesthetics, electrically stimulated smoking devices within electrical & electronic equipment, the preparation of wine or sparkling wine in food, food processing & cookware, and non electric simulated smoking devices in household cleaning & consumer products. Recorded exposure routes for articaine include dental, infiltration, ophthalmic, subcutaneous, and submucosal administration. At a molecular level, articaine interacts with ten recorded protein targets. It acts as an inhibitor of sodium channel protein type 1 subunit alpha (SCN1A), sodium channel protein type 4 subunit alpha (SCN4A), sodium channel protein type 5 subunit alpha (SCN5A), and sodium channel protein type 7 subunit alpha (SCN7A), in addition to six other proteins.