Glycopyrronium (CED0003122)

Record Information
Version1.0
Creation Date2026-04-05 10:46:31 UTC
Update Date2026-05-14 16:55:00 UTC
Accession NumberCHEM099499
Identification
Common NameGlycopyrronium
ClassSmall Molecule
Description
Glycopyrronium is an organic compound with the formula C19H28NO3 and an average molecular weight of 318.43 g/mol. Glycopyrronium belongs to the benzene and substituted derivatives, a class of benzenoids within the organic compounds. This compound is found in or released from four recorded sources, including dermatological preparations, drugs for obstructive airway diseases, drugs for functional gastrointestinal disorders, and antispasmodics in combination with psycholeptics. It is associated with pharmaceuticals and veterinary products. Recorded exposure routes for glycopyrronium include oral, intravenous, intramuscular, respiratory, and topical administration. At the molecular level, glycopyrronium interacts with five recorded protein targets. It acts as an antagonist of the Muscarinic acetylcholine receptor M1 (CHRM1), Muscarinic acetylcholine receptor M2 (CHRM2), Muscarinic acetylcholine receptor M3 (CHRM3), and Muscarinic acetylcholine receptor M4 (CHRM4), in addition to one other protein.
Contaminant TypeNot Available
Chemical Structure
SynonymsNot Available
Chemical FormulaC19H28NO3
Average Molecular Mass318.431 g/mol
Monoisotopic Mass318.207 g/mol
CAS Registry Number740028-90-4
IUPAC NameNot Available
Traditional NameNot Available
SMILESC[N+]1(C)CCC(C1)OC(=O)C(O)(C1CCCC1)C1=CC=CC=C1
InChI IdentifierInChI=1S/C19H28NO3/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3/q+1/t17-,19-/m0/s1
InChI KeyANGKOCUUWGHLCE-HKUYNNGSSA-N
Chemical Taxonomy
ClassificationNot classified
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Organoleptic EffectsNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted PropertiesNot Available
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyDeposition DateView
Predicted GC-MSPredicted GC-MS Spectrumsplash10-056r-8900000000-59a5fd70f741af9c9dd4Not AvailableView Spectrum
Toxicity Profile
Mechanism of ToxicityNot Available
Carcinogenicity (IARC Classification)Not Available
Minimum Risk LevelNot Available
SymptomsNot Available
TreatmentNot Available
Toxicity Values
Toxicity ValueUnitValue RangeOrganismDose DescriptorRoute of ExposurePredicted or ExperimentalReference
730.0Log mg/kg[410:1300]RatLD50oralpredictedNot Available
Health Effects
Health EffectRelationshipDirectionReference
Exposure Sources
Source IDSourceSectorReference
243Drugs for functional gastrointestinal disordersHealthcare, pharmaceuticals & veterinary productsNot Available
245Antispasmodics in combination with psycholepticsHealthcare, pharmaceuticals & veterinary productsNot Available
315Dermatological preparationsHealthcare, pharmaceuticals & veterinary productsNot Available
391Drugs for obstructive airway diseasesHealthcare, pharmaceuticals & veterinary productsNot Available
Pathways
0 pathways

No pathways found

No metabolic pathways have been associated with this synthetic chemical

Targets
StructureProteinUniProt IDOrganismRelationshipDetails
Click to view 3D structureMuscarinic acetylcholine receptor M2P10980Rattus norvegicusPredicted (SEA)5.13805
Click to view 3D structureMuscarinic acetylcholine receptor M1P08482Rattus norvegicusPredicted (SEA)2.95827
Click to view 3D structureMuscarinic acetylcholine receptor M3Q8VH26Cavia porcellusPredicted (SEA)1.40129
Click to view 3D structureMuscarinic acetylcholine receptor M1Q8WMX0Bos taurusPredicted (SEA)1.08989
Muscarinic acetylcholine receptor M1 structureClick to view 3D structureMuscarinic acetylcholine receptor M1P11229HumansPredicted (SEA)37.0562
Muscarinic acetylcholine receptor M2 structureClick to view 3D structureMuscarinic acetylcholine receptor M2P08172HumansPredicted (SEA)27.2472
Muscarinic acetylcholine receptor M3 structureClick to view 3D structureMuscarinic acetylcholine receptor M3P20309HumansPredicted (SEA)25.5345
Muscarinic acetylcholine receptor M4 structureClick to view 3D structureMuscarinic acetylcholine receptor M4P08173HumansPredicted (SEA)26.2352
Click to view 3D structureMuscarinic acetylcholine receptor M3P08483Rattus norvegicusPredicted (SEA)4.12601
Muscarinic acetylcholine receptor M5 structureClick to view 3D structureMuscarinic acetylcholine receptor M5P08912HumansPredicted (SEA)30.7504
Click to view 3D structureGlutathione S-transferase theta-1Q01579Rattus norvegicusPredicted (SEA)0.700643
Click to view 3D structurePancreatic alpha-amylaseP00689Rattus norvegicusPredicted (SEA)1.79053
Sodium-dependent dopamine transporter structureClick to view 3D structureSodium-dependent dopamine transporterQ01959HumansPredicted (SEA)373.988
D(3) dopamine receptor structureClick to view 3D structureD(3) dopamine receptorP35462HumansPredicted (SEA)686.864
Click to view 3D structureMuscarinic acetylcholine receptor M4P08485Rattus norvegicusPredicted (SEA)13.6236
Sodium-dependent noradrenaline transporter structureClick to view 3D structureSodium-dependent noradrenaline transporterP23975HumansPredicted (SEA)418.829
Sigma non-opioid intracellular receptor 1 structureClick to view 3D structureSigma non-opioid intracellular receptor 1Q99720HumansPredicted (SEA)679.702
5-hydroxytryptamine receptor 2B structureClick to view 3D structure5-hydroxytryptamine receptor 2BP41595HumansPredicted (SEA)623.728
Click to view 3D structuresn-1-specific diacylglycerol lipase ABHD11Q8NFV4HumansPredicted (SEA)3.03612
Cytochrome P450 2C19 structureClick to view 3D structureCytochrome P450 2C19P33261HumansPredicted (SEA)1624.32
Click to view 3D structureMuscarinic receptor 4Q8VH25Cavia porcellusPredicted (SEA)4.5931
Click to view 3D structureMuscarinic acetylcholine receptor DM1P16395Drosophila melanogasterPredicted (SEA)2.33548
Cytochrome P450 2D6 structureClick to view 3D structureCytochrome P450 2D6P10635HumansPredicted (SEA)3517.77
Neuronal acetylcholine receptor subunit alpha-7 structureClick to view 3D structureNeuronal acetylcholine receptor subunit alpha-7P36544HumansPredicted (SEA)276.91
Click to view 3D structuresn-1-specific diacylglycerol lipase ABHD11Q8K4F5Mus musculusPredicted (SEA)3.42537
Concentrations
Not Available
External Links
IdentifiersNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General ReferencesNot Available